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Books > Academic & Education > Professional & Technical > Neuroscience

Fundamental Neuroscience (Hardcover, 4th Revised edition): Larry R. Squire, Darwin Berg, Floyd E. Bloom, Sascha du Lac, Anirvan... Fundamental Neuroscience (Hardcover, 4th Revised edition)
Larry R. Squire, Darwin Berg, Floyd E. Bloom, Sascha du Lac, Anirvan Ghosh, …
R1,567 Discovery Miles 15 670 Within 7 - 11 working days

The fourth edition of "Fundamental Neuroscience" reinvents itself as an engrossing and comprehensive presentation of the discipline of neuroscience, from molecules to cognition. Thorough but succinct, and lavishly illustrated, the book builds from an introductory section that includes fundamental neuroanatomy and goes on to cover cellular and molecular neuroscience, development, sensory systems, motor systems, regulatory systems, and behavioral and cognitive neuroscience. The book has been retooled to better serve its audience in the neuroscience and medical communities.

The chapters include more than 100 boxes describing clinical conditions, techniques, and other special topics. Each chapter went through a thorough review process, giving the book an evenness of tone. The chapters are authored by outstanding working scientists who are experts on the topics they cover.
Selected for inclusion in Doody's Core Titles 2013, an essential collection development tool for health sciences libraries30% new material including new chapters on dendritic development and spine morphogenesis, chemical senses, cerebellum, eye movements, circadian timing, sleep and dreaming, and consciousnessAccompanying website for students and instructorsAdditional text boxes describing key experiments, disorders, methods, and conceptsMore than 650 four-color illustrations, micrographs, and neuroimages Multiple model system coverage beyond rats, mice, and monkeysExtensively expanded index for easier referencing

Development of the Nervous System (Hardcover, 3rd Revised edition): Dan H. Sanes, Thomas A. Reh, William A. Harris Development of the Nervous System (Hardcover, 3rd Revised edition)
Dan H. Sanes, Thomas A. Reh, William A. Harris
R1,252 Discovery Miles 12 520 Within 7 - 11 working days

"Development of the Nervous System" presents a broad and basic treatment of the established and evolving principles of neural development as exemplified by key experiments and observations from past and recent times. The text is organized ontogenically. It begins with the emergence of the neural primordium and takes a chapter-by-chapter approach in succeeding events in neural development: patterning and growth of the nervous system, neuronal determination, axonal navigation and targeting, neuron survival and death, synapse formation and developmental plasticity. Finally, in the last chapter, with the construction phase nearing completion, we examine the emergence of behavior. This new edition reflects the complete modernization of the field that has been achieved through the intensive application of molecular, genetic, and cell biological approaches. It is richly illustrated with color photographs and original drawings. Combined with the clear and concise writing, the illustrations make this a bookthat is well suited to students approaching this intriguing field for the first time.

Features - Thorough survey of the field of neural development - Concise but complete, suitable for a one semester course on upper level undergraduate or graduate level - Focus on fundamental principles of organogenesis in the nervous system - Integrates information from a variety of model systems, relating them to human nervous system development, including disorders of development - Systematically develops knowledge from the description of key experiments and results. - Organized ontologically - Carefully edited to be presented in one voice - New edition thoroughly updated and revised to include major new findings - All figures in full color, updated and revised - Specific attention on revising the chapter on cognitive and behavioral development to provide a foundation and outlook towards those very fast moving areas - Instructor website with figure bank andtest questions

Benefits - The only thorough textbook of Developmental Neuroscience on the market - Carefully structured and edited to map onto the syllabus of most developmental neuroscience courses - Priced to be affordable for undergraduates even in addition to broader textbooks - Carefully constructed instructor's website - Specifically designed to make teaching of complicated subjects easy and fun for instructors and students alike"

Cognition, Brain, and Consciousness - Introduction to Cognitive Neuroscience (Hardcover, 2nd Revised edition): Bernard J.... Cognition, Brain, and Consciousness - Introduction to Cognitive Neuroscience (Hardcover, 2nd Revised edition)
Bernard J. Baars, Nicole M. Gage
R1,319 Discovery Miles 13 190 Within 6 - 13 working days

This is the fully revised and updated second edition of the very sucessful introductory textbook on cognitive neuroscience. Written by two leading experts in the field, thisbook takes a unique thematic approach to introduce concepts of cognitive neurosciences, guiding students along a clear path to understand the latest findings whether or not they have a background in neuroscience. New to this edition are "Frontiers in Cognitive Neuroscience" text boxes; each one focuses on a leading researcher and their topic of expertise. There is a new chapter on Genes and Molecules of Cognition, and all other chapters have been thoroughly revised, based on the most recent discoveries.
New edition of a very successful textbookCompletely revisedto reflect new advances, and feedback from adopters and studentsIncludes a new chapter on Genes and Molecules of CognitionStudent Solutions available at http: //www.baars-gage.com/

For Teachers:

Rapid adoption and course preparation: A wide array of instructor support materials are available online including PowerPoint lecture slides, a test bank with answers, and eFlashcords on key concepts for each chapter. A textbook with an easy-to-understand thematic approach: in a way that is clear for students from a variety of academic backgrounds, the text introduces concepts such as working memory, selective attention, and social cognition.A step-by-step guide for introducing students to brain anatomy: color graphics have been carefully selected to illustrate all points and the research explained. Beautifully clear artist's drawings are used to 'build a brain' from top to bottom, simplifying the layout of the brain.

For students:

An easy-to-read, complete introduction to mind-brain science: all chapters begin from mind-brain functions and build a coherent picture of their brain basis. A single, widely accepted functional framework is used to capture the major phenomena. Learning Aids include a student support site with study guides and exercises, a new Mini-Atlas of the Brain and a full Glossary of technical terms and their definitions.Richly illustrated with hundreds of carefully selected color graphics to enhance understanding. "

Basic Neurochemistry - Principles of Molecular, Cellular and Medical Neurobiology (Hardcover, 8th Revised edition): George J.... Basic Neurochemistry - Principles of Molecular, Cellular and Medical Neurobiology (Hardcover, 8th Revised edition)
George J. Siegel, R. Wayne Albers, Donald Price, Scott Brady
R1,754 Discovery Miles 17 540 Within 7 - 11 working days

Basic Neurochemistry: Principles of Molecular, Cellular, and Medical Neurobiology, the outstanding and comprehensive classic text on neurochemistry, is now newly updated and revised in its Eighth Edition. For more than forty years, this text has been the worldwide standard for information on the biochemistry of the nervous system, serving as a resource for postgraduate trainees and teachers in neurology, psychiatry, and basic neuroscience, as well as for medical, graduate, and postgraduate students and instructors in the neurosciences. The text has evolved, as intended, with the science. It is also an excellent source of current information on basic biochemical and cellular processes in brain function and neurological diseases for continuing medical education and qualifying examinations. This text continues to be the standard reference and textbook for exploring the translational nature of neuroscience, bringing basic and clinical neuroscience together in one authoritative volume. Our book title reflects the expanded attention to these links between neurochemistry and neurologic disease.

This new edition continues to cover the basics of neurochemistry as in the earlier editions, along with expanded and additional coverage of new research from: Intracellular trafficking;Stem cells, adult neurogenesis, regeneration;Lipid messengers;Expanded coverage of all major neurodegenerative and psychiatric disorders;Neurochemistry of addiction;Neurochemistry of pain;Neurochemistry of hearing and balance;Neurobiology of learning and memory;Sleep;Myelin structure, development, and disease;Autism; andNeuroimmunology.

The new edition features:

* Completely updated text with new authors and material, and many entirely new chapters * Over 400 fully revised figures in splendid color * 61 chapters covering the range of cellular, molecular and medical neuroscience * Translational science boxes emphasizing the connections between basic and clinical neuroscience * Companion website at http: //elsevierdirect.com/companions/9780123749475"

A Combined MRI and Histology Atlas of the Rhesus Monkey Brain in Stereotaxic Coordinates (Hardcover, 2nd Revised edition):... A Combined MRI and Histology Atlas of the Rhesus Monkey Brain in Stereotaxic Coordinates (Hardcover, 2nd Revised edition)
Kadharbatcha S. Saleem, Nikos K. Logothetis
R3,475 Discovery Miles 34 750 Within 6 - 13 working days

The second edition of this atlas maps the detailed architectonic subdivisions of the cortical and subcortical areas in the macaque monkey brain using high-resolution magnetic resonance (MR) images and the corresponding histology sections in the same animal. This edition of the atlas is unlike anything else available as it includes the detailed cyto- and chemoarchitectonic delineations of the brain areas in all three planes of sections (horizontal, coronal, and sagittal) that are derived from the same animal. This is a significant progress because in functional imaging studies, such as fMRI, both the horizontal and sagittal planes of sections are often the preferred planes given that multiple functionally active regions can be visualized simultaneously in a single horizontal or sagittal section. This combined MRI and histology atlas is designed to provide an easy-to-use reference for anatomical and physiological studies in macaque monkeys, and in functional-imaging studies in human and non-human primates using fMRI and PET.
The first rhesus monkey brain atlas with horizontal, coronal, and sagittal planes of sections, derived from the same animal.Shows the first detailed delineations of the cortical and subcortical areas in horizontal, coronal, and sagittal plane of sections in the same animal using different staining methods.Horizonal series illustrates the dorsoventral extent of the left hemisphere in 47 horizontal MRI and photomicrographic sections matched with 47 detailed diagrams (Chapter 3). Coronal series presents the full rostrocaudal extent of the right hemisphere in 76 coronal MRI and photomicrographic sections, with 76 corresponding drawings (Chapter 4).Sagittal series shows the complete mediolateral extent of the left hemisphere in 30 sagittal MRI sections, with 30 corresponding drawings (Chapter 5). The sagittal series also illustrates the location of different fiber tracts in the white matter."Individual variability" - provides selected cortical and subcortical areas in three-dimensional MRI (horizontal, coronal, and sagittal MRI planes). For comparison, it also provides similar areas in coronal MRI section in six other monkeys. (Chapter 6)"Vasculature" - indicates the corresponding location of all major blood vessels in horizontal, coronal, and sagittal series of sections. Provides updated information on the cortical and subcortical areas, such as architectonic areas and nomenclature, with references, in chapter 2.Provides the sterotaxic grid derived from the in-vivo MR image.

The Mouse Brain in Stereotaxic Coordinates, Compact: Compact (Hardcover, 3rd Revised edition): George Paxinos, Keith B.J.... The Mouse Brain in Stereotaxic Coordinates, Compact: Compact (Hardcover, 3rd Revised edition)
George Paxinos, Keith B.J. Franklin
R1,457 Discovery Miles 14 570 Within 7 - 11 working days

The Mouse Brain in Stereotaxic Coordinates is the most widely used and cited atlas of the mouse brain in print. It provides researchers and students with both accurate stereotaxic coordinates for laboratory use, and detailed delineations and indexing of structures for reference. The Compact 3rd edition is both a major revision and an expansion of previous compact editions. The 100 high resolution digital photographs of the coronal plane of section from the third full edition now complement the coronal drawings. The photographs of the sections and the intermediate sections are also provided on the accompanying CD. In addition, the compact version has a large introduction on stereotaxic surgery and the use of the atlas in the lab, as well as a number of panoramic simplified diagrams for student instruction. The Compact 3rd edition is in 8.5 x 11 format and is spiral bound suitable for positioning next to microscopes and cryotomes.
* Delineations of 100 coronal diagrams, as fully revised for the 3rd edition


* 100 coronal photographic plates produced from directly scanned very high resolution images of the biological sections (done at the Allen Institute)


* Beginner's guide with 25 pages on how to do stereotaxic surgery, how to use the atlas, including how to match experimental sections against the atlas plates (e.g. what features of the brain change gradually and can be used as guides to location)


* 3 sagittal, 5 coronal and 2 horizontal simplified overview diagrams for students


* Surface views of the brain with labels over the major structures


* Uses the best ontology tree (nomenclature based on the development of the brain) so farconstructed with universal application across mammals


* CD providing electronic versions of all diagrams and photographs in different resolutions for downloads

Quantum Magnetic Resonance Imaging Diagnostics of Human Brain Disorders (Hardcover, New): Madan M. Kaila, Rakhi Kaila Quantum Magnetic Resonance Imaging Diagnostics of Human Brain Disorders (Hardcover, New)
Madan M. Kaila, Rakhi Kaila
R2,062 R1,386 Discovery Miles 13 860 Save R676 (33%) Within 7 - 11 working days

Magnetic resonance imaging (MRI) is a medical imaging technique used to visualize detailed internal structure of the body. This book discusses the recent developments in the field of MRI and its application to the diagnosis of human brain disorders. In addition, it reviews the newly emerging concepts and technology, based on the multi-coherence imaging (MQCI). It explains how computer packages can be used to generate images in diseased states and compare them to in vivo results. This will help improve the diagnosis of brain disorders based on the real-time events happening on atomic and molecular quantum levels. This is important since quantum-based MRI would enable clinicians to detect brain tumors at the very early stages.
Uses practical examples to explain the techniques - making it easier to understand the concepts
Uses diagrams to explain the physics behind the technique - avoiding the use of complicated mathematical formulae

Paxinos and Franklin's The Mouse Brain in Stereotaxic Coordinates (Hardcover, 4th Revised edition): George Paxinos, Keith... Paxinos and Franklin's The Mouse Brain in Stereotaxic Coordinates (Hardcover, 4th Revised edition)
George Paxinos, Keith B.J. Franklin
R2,944 Discovery Miles 29 440 Within 7 - 11 working days

In the years since its first publication, "Paxinos and Franklin's the Mouse Brain in Stereotaxic Coordinates" has received virtually universal acceptance in neuroscience as the authoritative source for stereotaxic coordinates and delineations. This atlas is constructed in the style of "The Rat Brain in Stereotaxic Coordinates," the most cited publication in neuroscience. The completely revised and updated 4e of "Paxinos and Franklin's the Mouse Brain in Stereotaxic Coordinates" features high-quality color plates scanned by the renowned microscopy unit of the Allen Institute for Brain Science. Constructed by the leaders in neuroanatomical atlas development, the new edition will maintain the position of the atlas as an indispensable resource for scientists working on the mouse brain.
100 coronal diagrams and accompanying photographic plates spaced at 120-m intervals; diagrams completely revised32 sagittal diagrams and accompanying photographic plates; diagrams completely revised30 horizontal diagrams and accompanying photographic plates; diagrams completely revisedThe most accurate and widely used stereotaxic coordinate systemNomenclature and abbreviations harmonized with the atlases of the brains of the rat, chick, marmoset, rhesus and humanElectronic diagrams available to purchasers of this book via booksite.elsevier.com/9780123910578/

Atlas of the Spinal Cord - Mouse, Rat, Rhesus, Marmoset, and Human (Hardcover): Gulgun Sengul, Charles Watson, Ikuko Tanaka,... Atlas of the Spinal Cord - Mouse, Rat, Rhesus, Marmoset, and Human (Hardcover)
Gulgun Sengul, Charles Watson, Ikuko Tanaka, George Paxinos
R2,762 Discovery Miles 27 620 Within 6 - 13 working days

The "Atlas of the Spinal Cord" is the first comprehensive atlas of rodent and primate spinal cords. This atlas features histological images and labeled drawings of every segment from rat, mouse, marmoset monkey, rhesus monkey, and human spinal cords. Nissl-stained section images and matching drawings for each segment are supplemented by up to four histochemical or immunohistochemical images on a facing page. The neuron groups supplying major limb muscles are identified in each species. Constructed by the established leaders in neuroanatomical atlas development, this new atlas will be the indispensible resource for scientists who work on rodent or primate spinal cord.
Full-color photographic images of Nissl-stained sections from every spinal cord segment in each of two rodent and three primate species over 160 Nissl platesComprehensively labeled diagrams to accompany each Nissl-stained section over 160 diagramsMore than 500 photographic images of sections stained for AChE, ChAT, parvalbumin, NADPH- diaphorase, calretinin, or other markers to supplement the Nissl-stained imagesDigital versions of diagrams are available to purchasers of this book via a website "

The Neuroscience of Sleep (Hardcover): Robert Stickgold, Matthew P. Walker The Neuroscience of Sleep (Hardcover)
Robert Stickgold, Matthew P. Walker
R1,507 Discovery Miles 15 070 Within 7 - 11 working days

Sleep is the natural state of bodily rest, common to all mammals and birds and also seen in many reptiles, amphibians and fish. For most species, regular sleep is essential for survival, yet the specific purposes of sleep are still only partly clear and are the subject of intense research. This volume is comprised of the editors selection of the most relevant articles on sleep from the "Encyclopedia of Neuroscience, " resulting in the first comprehensive collection of introductory articles on the neuroscience of sleep.Articles explore sleep s impact on neural functioning, sleep disorders, the relation between sleep and other clinical disorders, a look at sleep from a developmental perspective, and more.

* Chapters offer impressive scope with topics addressing neural functioning, disorders, development, and more, carefully selected by one of the most preeminent sleep researchers

* Richly illustrated in full color with over 100 figures

* Contributors represent the most outstanding scholarship in the field, with each chapter providing fully vetted and reliable expert knowledge"

The Human Nervous System (Hardcover, 3rd Revised edition): Juergen K. Mai, George Paxinos The Human Nervous System (Hardcover, 3rd Revised edition)
Juergen K. Mai, George Paxinos
R3,615 Discovery Miles 36 150 Within 6 - 13 working days

The previous two editions of the "Human Nervous System "have been the standard reference for the anatomy of the central and peripheral nervous system of the human. The work has attracted nearly 2,000 citations, demonstrating that it has a major influence in the field of neuroscience. The 3e is a complete and updated revision, with newchapters covering genes and anatomy, gene expression studies, and glia cells. The book continues to be an excellent companion to the "Atlas of the Human Brain," and a common nomenclature throughout the book is enforced. Physiological data, functional concepts, and correlates to the neuroanatomy of the major model systems (rat and mouse) as well as brain function round out the new edition.
Adopts standard nomenclature following the new scheme by Paxinos, Watson, and Puelles and aligned with the Mai et al. "Atlas of the Human Brain" (new edition in 2007)Full color throughout with many new and significantly enhanced illustrationsProvides essential reference information for users in conjunction with brain atlases for the identification of brain structures, the connectivity between different areas, and to evaluate data collected in anatomical, physiological, pharmacological, behavioral, and imaging studies"

The Mouse Nervous System (Hardcover): Charles Watson, George Paxinos, Luis Puelles The Mouse Nervous System (Hardcover)
Charles Watson, George Paxinos, Luis Puelles
R3,378 Discovery Miles 33 780 Within 7 - 11 working days

"The Mouse Nervous System" provides a comprehensive account of the central nervous system of the mouse. The book is aimed at molecular biologists who need a book that introduces them to the anatomy of the mouse brain and spinal cord, but also takes them into the relevant details of development and organization of the area they have chosen to study. "The Mouse Nervous System" offers a wealth of new information for experienced anatomists who work on mice. The book serves as a valuable resource for researchers and graduate students in neuroscience.
Systematic consideration of the anatomy and connections of all regions of the brain and spinal cord by the authors of the most cited rodent brain atlasesA major section (12 chapters) on functional systems related to motor control, sensation, and behavioral and emotional statesA detailed analysis of gene expression during development of the forebrain by Luis Puelles, the leading researcher in this areaFull coverage of the role of gene expression during development and the new field of genetic neuroanatomy using site-specific recombinasesExamples of the use of mouse models in the study of neurological illness

Context Effects on Embodied Representation of Language Concepts (Paperback, New): Jie Yang Context Effects on Embodied Representation of Language Concepts (Paperback, New)
Jie Yang
R430 Discovery Miles 4 300 Within 7 - 15 working days

Embodied theories claim that semantic representations are grounded in sensorimotor systems, but the contribution of sensorimotor brain areas in representing meaning is still controversial. One current debate is whether activity in sensorimotor areas during language comprehension is automatic. Numerous neuroimaging studies reveal activity in perception and action areas during semantic processing that is automatic and independent of context, but increasing findings show that involvement of sensorimotor areas and the connectivity between word-form areas and sensorimotor areas can be modulated by contextual information. "Context Effects on Embodied Representation of Language Concepts "focuses on these findings and discusses the influences from word, phrase, and sentential contexts that emphasize either dominant conceptual features or non-dominant conceptual features.
Reviews the findings about contextual modularityClarifies the invariant and flexible features of embodied lexical-semantic processing

Fundamentals of Cognitive Neuroscience - A Beginner's Guide (Paperback): Bernard J. Baars, Nicole M. Gage Fundamentals of Cognitive Neuroscience - A Beginner's Guide (Paperback)
Bernard J. Baars, Nicole M. Gage
R851 Discovery Miles 8 510 Within 7 - 11 working days

Fundamentals of Cognitive Neuroscience is a comprehensive and easy-to-follow guide to cognitive neuroscience. Winner of a 2013 Most Promising New Textbook Award from the Text and Academic Authors Association, this book was written by two leading experts in the field to be highly accessible to undergraduates with limited neuroscience training. It covers all aspects of the field-the neural framework, sight, sound, consciousness, learning/memory, problem solving, speech, executive control, emotions, socialization and development-in a student-friendly format with extensive pedagogy and ancillaries to aid both the student and professor. This introductory text takes a unique thematic approach, guiding students along a clear path to understand the latest findings whether or not they have a background in neuroscience. It includes case studies and everyday examples designed to help students understand the more challenging aspects of the material. It is richly illustrated with carefully selected color graphics to enhance understanding. Enhanced pedagogy highlights key concepts for the student and aids in teaching. Chapter outlines, study questions, glossary, and image collection are also available on the student's companion website. Ancillary support saves instructors time and facilitates learning; test questions, image collection, and lecture slides are available on the instructor's manual website. This book will be of interest to undergraduate students in Neuroscience, Psychology, and related disciplines that teach cognitive neuroscience.

The Rat Brain in Stereotaxic Coordinates: Compact (Spiral bound, 6th Revised edition): George Paxinos, Charles Watson The Rat Brain in Stereotaxic Coordinates: Compact (Spiral bound, 6th Revised edition)
George Paxinos, Charles Watson
R1,478 Discovery Miles 14 780 Within 7 - 11 working days

The Rat Brain in Stereotaxic Coordinates, Compact Sixth Edition is a smaller sized (8.5 x11inch), abridged version of the most referenced work in neuroscience (over 35,000 citations for this atlas). The compact edition provides the coronal plates and diagrams of the current sixth edition in a smaller more convenient spiral format and at a student friendly price. This book includes an introduction for students to some of the major current concepts in neuroanatomy: neuromeres and brain development. Students and seasoned researchers will find herein the first major unified nomenclature ontology tree based on development. The atlas features 161 coronal photographic plates and 161 juxtaposed diagrams. The diagrams are in color, but the photographs are in black and white. The full-sized sixth edition is in full color and also features the sagittal and horizontal planes.
* 161 coronal photographic diagrams and accompanying 161 photographic plates spaced at 120 micron intervals
* Diagrams are identical to those of the full Sixth Edition
* Delineations of over 900 brain structures
* The most accurate stereotaxic coordinate system
* CD includes drawings in pdf, eps and ai formats and color images
* Support website providing electronic versions of all diagrams and photographs in different resolutions for downloads

Neuroinflammation (Hardcover): Alireza Minagar Neuroinflammation (Hardcover)
Alireza Minagar
R2,381 R538 Discovery Miles 5 380 Save R1,843 (77%) Within 7 - 11 working days

Inflammation is a central mechanism in many neurological diseases, including stroke, multiple sclerosis, and brain trauma as well as meningitis and contributes to the generation of pain. We are now beginning to understand the impact of the immune system on different nervous system functions and diseases, ranging from damage through tolerance to modulation and repair.

This book discusses some of the more common neuro-inflammatory diseases. Topics covered include multiple sclerosis, optic neuritis and Susac syndrome.
Comprehensive review of the latest developments in neuroinflammation
Includes contributions from leading authorities

Mouse Behavioral Testing - How to Use Mice in Behavioral Neuroscience (Hardcover): Douglas Wahlsten Mouse Behavioral Testing - How to Use Mice in Behavioral Neuroscience (Hardcover)
Douglas Wahlsten
R2,334 Discovery Miles 23 340 Within 7 - 15 working days

This book presents the essentials of behavioral test methodology needed for effective study planning and high quality behavioral data collection on laboratory mice. The broad scope of behavioral testing in relation to the neurosciences is discussed, as are thefine details of varioustest situations. Mistakes made in past research are scrutinized and lessons are drawn about how to avoid them in future work. Diverse factors that can influence the results of behavioral experiments are discussed, ranging from the specific parameters employed in a test to the laboratory environment outside the test situation itself. Throughout the book, emphasis is placed on special issues that arise when testing genetically different mice, including inbred strains and mice with targeted mutations. This knowledge will assist an investigator who lacks formal training in behavioral psychology to build a behavioral testing lab and insure that its output meets current standards of good practice in behavioral neuroscience research.

The book will be a convenient manual of procedures for daily use in studies of mouse behavior. It will be of interest even to experienced behavioural researchers, but of particular value to scientists just beginning work with mice, including undergraduate and graduate students as well as postdoctoral investigators who want to collect phenotypic data with knockout and other genetically defined mice. Constructed from materials used in a long running course on Advanced Animal Behavior at University of North Carolina-Greensboro, the book is an ideal text for a course on behavioral testing.
A guide to running a behavioral testing lab, including the many aspects of mouse research beyond the confines of the specific testDiagrams and photographs are shown for many kinds of apparatus and test situations with sufficient details such as dimensions to enable building of replicasProvides step-by-step instructions on planning and executing behavioral experiments in order to run them successfullyA companion website will provide access to statistical utilities in Excel and test protocols, examples of real documents used for published studies, and video clips of the mice behaviors resulting from various tests"

Principles of Behavioral Genetics (Paperback, New): Robert R.H. Anholt, Trudy F.C. Mackay Principles of Behavioral Genetics (Paperback, New)
Robert R.H. Anholt, Trudy F.C. Mackay
R1,485 Discovery Miles 14 850 Within 7 - 15 working days

How do genes determine behavior? How much of behavior is nature versus nurture? How do behaviors evolve? Anholt and Mackay, leading scholars in the field of behavioral genetics, address these questions and much more in this comprehensive textbook that defines the emerging field of behavioral genetics. The provides a range of examples, such as laboratory studies on flies and mice, field observations on species as diverse as butterflies and meerkats, and human behavioral disorders. The book blends classical and modern genetic principles with neurobiological and ecological perspectives to teach students how to find and map genes that affect behaviors, as well as how the coordinated expression of ensembles of these genes enables the nervous system to express complex behaviors in response to changes in the environment. Principles of Behavioral Genetics introduces us to the fascinating science that aims to understand how our genes determine what makes us tick.
Principles of Behavioral Genetics presents a comprehensive overview of the relationship between genes, brain and behavior. Introductory chapters provide clear explanations of basic processes of the nervous system and fundamental principles of genetics of complex traits without excessive statistical jargon. Individual chapters describe the genetics of social interactions, olfaction and taste, memory and learning, circadian behavior, locomotion, sleep, and addiction, as well as the evolution of behavior. Whereas the focus is on genetics, neurobiological and ecological aspects are also included to provide intellectual breadth. The book uses examples that span the gamut from classical model organisms to non-model systems and human biology, and include both laboratory and field studies. Samples of historical information accentuate the text to provide the reader with an appreciation of the history of the field. All chapters contain general overviews, concise summaries, study questions that promote not only memorization but also contemplation of the material, and recommendations for further in-depth reading. An extensive glossary that defines the terminology used in the book is included. This textbook encompasses a broad definition of the emerging science of behavioral genetics.
* Defines the emerging science of behavioral genetics
* Engagingly written by two leading experts in behavioral genetics
* Clear explanations of basic quantitative genetic, neurogenetic and genomic applications to the study of behavior
* Numerous examples ranging from model organisms to non-model systems and humans
* Concise overviews and summaries for each chapter

Managing Relationships with Industry - A Physician's Compliance Manual (Paperback): Steven C Schachter, William Mandell,... Managing Relationships with Industry - A Physician's Compliance Manual (Paperback)
Steven C Schachter, William Mandell, Scott Harshbarger, Randall Grometstein
R655 Discovery Miles 6 550 Within 7 - 11 working days

Now more than ever, doctors are being targeted by government prosecutors and whistleblowers challenging the legality of their relationships with drug and device companies. With reputations at stake and the risk of civil and criminal liability, it is incumbent upon doctors to protect themselves.
Managing Relationships with Industry: A Physician s Compliance Manual is an indispensable resource for doctors, professional societies, academic medical centers, community hospitals, and group practices struggling to understand the ever changing law and ethical standards on interactions with pharmaceutical and device companies. It is the first comprehensive summary of the law and ethics on physician relationships with industry written for the physician. Authored by a former state Attorney General, Harvard Medical School Professor, health care lawyer and professor of ethics, Managing Relationships approaches the topic from a balanced and reasoned perspective adding to the on-going national dialogue and debate on the proper limits to medicine s relationship with industry.
* The first complete and up-to-date summary and analysis of the law and ethics on physician-industry relationships
* Focuses on major enforcement actions and whistleblower lawsuits and the lessons learned for physicians
* Provides options and guidance for maintaining compliant relationships and avoiding traps for the unwary
* Covers both drug and device company relationships
* Summarizes the types of industry relationships that are necessary and productive and those that are harmful and abusive
* Details the law and ethics for each type of relationship including gifts, off-label uses and marketing, CME, speaker s bureaus, free samples, grants, consulting arrangements, etc.
* Includes sample contracts for permissible consulting and CME speaker engagements"

Primer on the Autonomic Nervous System (Paperback, 3rd Revised edition): David W. Robertson, Italo Biaggioni, Ronald J.... Primer on the Autonomic Nervous System (Paperback, 3rd Revised edition)
David W. Robertson, Italo Biaggioni, Ronald J. Polinsky, Geoffrey Burnstock, Julian F. R. Paton, …
R1,401 Discovery Miles 14 010 Within 7 - 11 working days

The Primer on the Autonomic Nervous System presents, in a readable and accessible format, key information about how the autonomic nervous system controls the body, particularly in response to stress. It represents the largest collection of world-wide autonomic nervous system authorities ever assembled in one book. It is especially suitable for students, scientists and physicians seeking key information about all aspects of autonomic physiology and pathology in one convenient source. Providing up-to-date knowledge about basic and clinical autonomic neuroscience in a format designed to make learning easy and fun, this book is a must-have for any neuroscientist s bookshelf
* Greatly amplified and updated from previous edition including the latest developments in the field of autonomic cardiovascular regulation and neuroscience
* Provides key information about all aspects of autonomic physiology and pathology
* Discusses stress and how its effects on the body are mediated
* Compiles contributions by over 140 experts on the autonomic nervous system"

The Brain - An Introduction to Functional Neuroanatomy (Hardcover): Charles Watson, Matthew Kirkcaldie, George Paxinos The Brain - An Introduction to Functional Neuroanatomy (Hardcover)
Charles Watson, Matthew Kirkcaldie, George Paxinos
R861 Discovery Miles 8 610 Within 7 - 11 working days

The authors of the most cited neuroscience publication, "The Rat Brain in Stereotaxic Coordinates," have written this introductory textbook for neuroscience students. The text is clear and concise, and offers an excellent introduction to the essential concepts of neuroscience.

Based on contemporary neuroscience research rather than old-style medical school neuroanatomy

Thorough treatment of motor and sensory systems

A detailed chapter on human cerebral cortex

The neuroscience of consciousness, memory, emotion, brain injury, and mental illness

A comprehensive chapter on brain development

A summary of the techniques of brain research

A detailed glossary of neuroscience terms

Illustrated with over 130 color photographs and diagrams

This book will inspire and inform students of neuroscience. It is designed for beginning students in the health sciences, including psychology, nursing, biology, and medicine.
Clearly and concisely written for easy comprehension by beginning students

Based on contemporary neuroscience research rather than the concepts of old-style medical school neuroanatomy

Thorough treatment of motor and sensory systems

A detailed chapter on human cerebral cortex

Discussion of the neuroscience of conscience, memory, cognitive function, brain injury, and mental illness

A comprehensive chapter on brain development

A summary of the techniques of brain research

A detailed glossary of neuroscience terms

Illustrated with over 100 color photographs and diagrams

Handbook of Mammalian Vocalization - An Integrative Neuroscience Approach (Hardcover): Stefan M. Brudzynski Handbook of Mammalian Vocalization - An Integrative Neuroscience Approach (Hardcover)
Stefan M. Brudzynski
R3,049 Discovery Miles 30 490 Within 7 - 11 working days

The present proposal offers an outline of the planned major Handbook on Mammalian Vocalization, which fills a clear niche existing in the science book literature and on the market. The Handbook is designed as a broad and comprehensive, but well-balanced book, written from the neuroscience point of view in the broad sense of this term. Only a few issues will be reduced, which are extensively covered in other recent book publications. The Handbook is planned in a unique way and will not directly compete with other books on the market. This well-illustrated Handbook will pay a particular attention to systematically organized details but also to the explanatory style of the text and internal cohesiveness of the content, so the successive chapters will gradually develop a consistent story without losing the inherent complexity. Studies from many species will be included, however, rodents will dominate, as most of the brain investigations were done on these species.
The leading idea of the Handbook is that vocalizations evolved as highly adaptive specific signals, which are selectively picked up by the brain. The brain serves as a receptor and behavioural amplifier. Brain systems will be described, which allow vocal signals rapidly changing the entire state of the organism and trigger vital biological responses, usually also with accompanying emission of vocalizations. Integrative brain functions leading to vocal outcome will be described, along with the vocalization generators and motor output to larynx and other supportive motor subsystems. The last sections of the Handbook will explain bioacoustic structure of vocalizations, present understanding of information coding, and origins of the complex semiotic/ semantic content of vocalizations in social mammals.
The Handbook is thought as a major source of information for professionals from many fields, with neuroscience approach as a common denominator. The handbook is planned to provide consistent and unified understanding of all major aspects of vocalization in a monographic manner, and at the same time, to give an encyclopaedic overview of major topics associated with vocalization from molecular/ cellular level to behavior and cognitive processing. It is planned to be written in a strictly scientific way but clear enough to serve not only for specialized researchers in different fields of neuroscience but also for academic teachers of neuroscience, including behavioural neuroscience, affective neuroscience, clinical neuroscience, neuroethology, biopsychology, neurolingusitics, speech pathology, and other related fields, and also for research fellows, graduate and other advanced students, who widely need such a source publication.

Features
The first comprehensive handbook on what we know about vocalization in Mammalians
Benefits
Currently the information on this topic is dispersed over journal articles and book chapters across a number of journals and books with different focus. The handbook will provide the researcher interested in animal and human communication, as well as the researcher interested in the control of motor systems by the brain finally with a comprehensive reference on the topic. The handbook will have great influence in providing for the first time a bridge from information on animal communication and it's nervous system control to the neural control of language and language development in the human.
Features
Carefully edited, the handbook provides an integrated overview of the area
Benefits
Instructors and students will find this handbook a useful background information in courses of animal and human communication, speech and language, the neuroethology of sound production and sound perception, and similar
Features
International list of highly regarded contributors, including Jaak Pankseep (Washington State University), David McFarland (Oxford), John D. Newman (NIH ? Unit on Developmental Neuroethology), Gerd Poeggel (Leipzig), Shiba Keisuke (Chiba City, Japan), and others, tightly edited by a single, well regarded editor who has edited a special issue in Behavioral Brain Research on the topic before.
Benefits
Complete overview with contributions from the leading researchers from eleven countries in North America, Europe, Japan and Australia, presented in an integrated, tightly edited book.

The Rat Brain in Stereotaxic Coordinates (Hardcover, Hard Cover ed): George Paxinos, Charles Watson The Rat Brain in Stereotaxic Coordinates (Hardcover, Hard Cover ed)
George Paxinos, Charles Watson
R3,272 Discovery Miles 32 720 Within 6 - 13 working days

This completely revised edition of The Rat Brain in Stereotaxic Coordinates, the second most cited book in science, represents a dramatic update from the previous edition. Based on a single rat brain, this edition features an entirely new coronal set of tissue cut in regular 120 micron intervals with accompanying photographs and drawings of coronal, horizontal and sagittal sections of this new set. The use of the single brain allows for greater consistency between sections, while advances in histochemistry techniques provides increased refinement in the definition of brain areas, making this the most accurate and detailed stereotaxic rat atlas produced to date. The atlas will also include a CD-ROM featuring all of the graphics and text. Every lab working with the rat as an experimental animal model will want to use this book as their atlas of choice.
This book is also available in a softcover spiral binding at the same price.
* Includes twice as many coronal sections, nissl plates, and sagittal plates as the previous edition
* Uses a single rat brain allowing for better consistency and better delineations in the line drawings of structures
* Provides improved stereotaxic coordinates at a higher level of detail
* Accompanying CD-ROM features graphics and text
* Now available as hardcover version and softcover version with a spiral binding at the same price.

Axon Growth and Regeneration, Part 2 (Hardcover, New): Jeffrey Louis Goldberg, Ephraim F. Trakhtenberg Axon Growth and Regeneration, Part 2 (Hardcover, New)
Jeffrey Louis Goldberg, Ephraim F. Trakhtenberg
R4,250 Discovery Miles 42 500 Within 7 - 15 working days

Leading authors review state-of-the-art in their field of investigation and provide their views and perspectives for future research
Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered
All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist
Leading authors review state-of-the-art in their field of investigation and provide their views and perspectives for future research
Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered
All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist

New Perspectives of Central Nervous System Injury and Neuroprotection (Hardcover, New): Hari Shanker Sharma New Perspectives of Central Nervous System Injury and Neuroprotection (Hardcover, New)
Hari Shanker Sharma
R4,021 Discovery Miles 40 210 Within 7 - 15 working days

Central nervous system (CNS) diseases such as Alzheimer s disease, Parkinson s disease, and amyotrophic lateral sclerosis affect a large number of populations worldwide for which no suitable cure is currently available. In addition, stroke, nanoparticle intoxication, diabetes, hypertension, and psychostimulant abuse either alone or in combination are capable of inducing potential brain damage. Thus, there is an urgent need to expand our knowledge to find suitable therapeutic strategies to enhance neurorepair processes in such diseases.

This volume presents neuroprotection and novel therapeutic strategies developed in the last 5 years by 12 world leaders in the field. The term neuroprotection means rescuing neuronal and non-neuronal cells together. The cerebral endothelium that constitutes the anatomical and physiological site of the blood-brain barrier (BBB) is one of the most important non-neural cells in the CNS. Any distortion of the BBB leads to brain diseases and restoration of the barrier results in neuroprotection. Thus, the BBB appears to be the "gateway" for neurological diseases and neurorepair. However, to treat brain tumors or infarcts, new therapeutic strategies are needed to enhance brain drug delivery using nanotechnology. In addition, apart from conventional drugs, restoration of BBB function could also be achieved by means of antibodies directed against specific proteins, neurotransmitters or exogenous supplement of neurotrophic factors. Since co-morbidity factors e.g., hypertension, diabetes, and exposure of nanoparticles could complicate the pathogenesis of neurological disorders either an enhanced dose of the drug or nanodelivery of a combination of several drugs is needed to achieve neuroprotection.

This volume of "International Review of Neurobiology" is the first to discuss novel therapeutic strategies in situations of neurological disorders in combination with different co-morbidity factors.

Reviews written by experts in such a way thatprovides basic knowledge for beginners and advanced information for researchers and experts.

New aspects of Neurodegenerative diseasessuch as;Alzheimer s Disease, Parkinson s Disease, Amyotrophic Lateral Sclerosis are presented with thelatest therapeutic measures.

Exacerbation of brain pathology in hypertension or diabetes is discussed for the first time.

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