Familiarity with the mechanisms of eukaryotic gene regulation is
now essential for scientists and students in both clinical and
basic disciplines. However, the vast array of transcription
factors, which are central to such regulation, can prove daunting
to students and newcomers to this fascinating field of molecular
genetics. The Third Edition of Eukaryotic Transcription Factors
provides the reader with a clear and concise understanding not only
of transcription factors, but also of their vital role in the
regulation of transcription in different cell types during
development and in disease.
Revised and completely up-to-date, the Third Edition of Eukaryotic
Transcription Factors has been extensively rewritten to reflect the
rapid advances in the field. These include the emerging roles of
specific co-activator molecules such as CBP in the action of a
number of different transcription factors emphasizing particularly
their ability to modulate chromatin structure. New sections cover
current methods for determining DNA binding specificity, regulation
by protein degradation and processing, Pax family transcription
factors, and novel anti-oncogenic transcription factors, as well as
a discussion of transcription factors in human diseases. A special
new color section illustrates the various aspects of transcription
Emphasising common motifs, themes and mechanisms this volume
* Major families of eukaryotic transcription factors
* Mechanisms of gene activation and repression
* Structure-function relationships
* Their roles in inducible and cell type-specific gene expression,
development, differentiation, and human diseases including
* Methods of study "in vivo" and "in vitro"
Academic Press Inc
|Country of origin:
David S. Latchman
||Electronic book text
Is the information for this product incomplete, wrong or inappropriate?
Let us know about it.
Does this product have an incorrect or missing image?
Send us a new image.
Is this product missing categories?
Add more categories.
Review This Product
No reviews yet - be the first to create one!