Because of the dearth of experimental animal models of psychiatric
disorders, the study of the effect of the disease state is only
possible in tissue derived from patients vs. controls, especially
in the target tissue of disease-related changes in the brain. The
human postmortem brain offers the most appropriate experimental
paradigm towards understanding the etiology of psychiatric
disorders. The availability of post-mortem human samples from
psychiatric patients and comparison groups in recent years has
contributed prominently to the accumulating body of information
leading to a better understanding of these disorders. This is the
first book to summarize this research approach and the meaningful
data which has recently been acquired.
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