Advances in knowledge and technology have revolutionized the
process of drug development, making it possible to design drugs for
a given target or disease. Building on the foundation laid by the
previous three editions, Smith and Williams' Introduction to the
Principles of Drug Design and Action, Fourth Edition includes the
latest information on topics such as gene therapy, computer-aided
design, and molecular techniques including proteomics. Using
real-world examples that illustrate the principles of drug design,
the author explores the discovery of lead compounds and their
manipulation in the production of non-toxic, metabolically stable
drug candidates that will interact with target receptors in a
predicted fashion. See what's new in the Fourth Edition: Fully
updates and expands the contents Coverage of agonists and
antagonists of neuro-transmitters Information on the design of
stable peptide-like drugs The human genome and its impact on drug
discovery and development Advances in therapy and pharmacokinetics
Adopting a from-the-bench-to-the-marketplace approach, the book
provides a thorough grounding in rational drug design. It
emphasizes principles and elucidates a framework for basic drug
design into which current and, more importantly, future drugs will
|Country of origin:
H. John Smith
• Hywel Williams
||Electronic book text
||4th New edition
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