It offers a unique up-to-date overview on research results on the defective execution of apoptosis and the incomplete clearance of apoptotic cells. The molecular and cellular mechanisms involved are described in detail. As a possible consequence of apoptotic dysfunction, the development of severe autoimmune diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus) is discussed. An outlook on future research topics includes the evaluation of novel therapeutic strategies.
It offers a unique up-to-date overview on research results on the defective execution of apoptosis and the incomplete clearance of apoptotic cells. The molecular and cellular mechanisms involved are described in detail. As a possible consequence of apoptotic dysfunction, the development of severe autoimmune diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus) is discussed. An outlook on future research topics includes the evaluation of novel therapeutic strategies.
Imprint | Wiley-Blackwell |
Country of origin | United States |
Release date | 2006 |
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Authors | Joachim Kalden, Martin Herrmann |
Editors | Joachim R. Kalden, Martin Herrmann |
Format | Electronic book text |
Pages | 381 |
ISBN-13 | 978-1-280-52038-9 |
Barcode | 9781280520389 |
Categories | |
LSN | 1-280-52038-8 |