This book guides medicinal chemists in how to implement early ADMET
testing in their workflow in order to improve both the speed and
efficiency of their efforts. Although many pharmaceutical companies
have dedicated groups directly interfacing with drug discovery, the
scientific principles and strategies are practiced in a variety of
different ways. This book answers the need to regularize the drug
discovery interface; it defines and reviews the field of ADME for
medicinal chemists. In addition, the scientific principles and the
tools utilized by ADME scientists in a discovery setting, as
applied to medicinal chemistry and structure modification to
improve drug-like properties of drug candidates, are examined.
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