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ATN1 is a protein found in nervous tissue.It is associated with a
form of trinucleotide repeat disorder known as
"dentatorubral-pallidoluysian atrophy" or
"dentatorubropallidoluysian atrophy."Dentatorubral pallidoluysian
atrophy is a rare neurodegenerative disorder characterized by
cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and
dementia. The disorder is related to the expansion of a
trinucleotide repeat within this gene. The encoded protein includes
a serine repeat and a region of alternating acidic and basic amino
acids, as well as the variable glutamine repeat. Alternative
splicing results in two transcripts variants that encode the same
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