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Cbfa2t2 (Paperback) Loot Price: R713
Discovery Miles 7 130
Cbfa2t2 (Paperback): Lambert M. Surhone, Mariam T. Tennoe, Susan F. Henssonow
Cbfa2t2 (Paperback): Lambert M. Surhone, Mariam T. Tennoe, Susan F. Henssonow

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Cbfa2t2 (Paperback)

Lambert M. Surhone, Mariam T. Tennoe, Susan F. Henssonow

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Loot Price R713 Discovery Miles 7 130 | Repayment Terms: R66 pm x 12*

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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Protein CBFA2T2 is a protein that in humans is encoded by the CBFA2T2 gene.In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 (AML1) gene fused to the 3'-region of the CBFA2T1 (MTG8) gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. The protein encoded by this gene binds to the AML1-MTG8 complex and may be important in promoting leukemogenesis. Several transcript variants are thought to exist for this gene, but the full-length natures of only three have been described.

General

Imprint: Betascript Publishing
Country of origin: Germany
Release date: March 2011
First published: March 2011
Editors: Lambert M. Surhone • Mariam T. Tennoe • Susan F. Henssonow
Dimensions: 152 x 229 x 5mm (L x W x T)
Format: Paperback - Trade
Pages: 76
ISBN-13: 978-6135253641
Barcode: 9786135253641
Categories: Promotions
Books > Science & Mathematics > Biology, life sciences > Zoology & animal sciences
Books > Science & Mathematics > Biology, life sciences > Zoology & animal sciences > General
LSN: 6135253646

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