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Epidermal growth factor receptor kinase substrate 8 is an enzyme
that in humans is encoded by the EPS8 gene.This gene encodes a
member of the EPS8 family. This protein contains one PH domain and
one SH3 domain. It functions as part of the EGFR pathway, though
its exact role has not been determined. Highly similar proteins in
other organisms are involved in the transduction of signals from
Ras to Rac and growth factor-mediated actin remodeling. Alternate
transcriptional splice variants of this gene have been observed but
have not been thoroughly characterized.
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