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Lambert M. Surhone, Mariam T. Tennoe, Susan F. Henssonow
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Transducin (beta)-like 1X-linked, also known as TBL1X, is a protein
which in humans is encoded by the TBL1X gene.The protein encoded by
this gene has sequence similarity with members of the WD40
repeat-containing protein family. The WD40 group is a large family
of proteins, which appear to have a regulatory function. It is
believed that the WD40 repeats mediate protein-protein interactions
and members of the family are involved in signal transduction, RNA
processing, gene regulation, vesicular trafficking, cytoskeletal
assembly and may play a role in the control of cytotypic
differentiation. This encoded protein is found as a subunit in
corepressor SMRT (silencing mediator for retinoid and thyroid
receptors) complex along with histone deacetylase 3 protein.
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