Unique-Event Polymorphism (Paperback)

Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. In genetic genealogy a unique-event polymorphism (UEP) is a genetic marker that corresponds to a mutation which is likely to occur so infrequently that it is believed overwhelmingly probable that all the individuals who share the marker, worldwide, will have inherited it from the same common ancestor, and the same single mutation event.Generally, UEP is an allele for which all copies derive from a single mutational event.In genetic genealogy the mutations considered to be UEPs can be any germline mutation usually single-nucleotide polymorphisms - the replacement of one letter by another in the DNA sequence, and the terms UEP and SNP are often loosely used interchangeably. But UEPs may also be large-scale additions, such as the YAP insertion which defines Y-DNA haplogroups D and E, inversion or deletions.