Vitamin D deficiency has suggested that not only a biochemical
abnormality, but is also associated with adverse effect of poor
bone mineralization in growing children and adolescents. The
findings of the present study clearly demonstrate that vitamin D
deficiency occurs in a high proportion of adolescent girls,
regardless of what 25(OH)D level is used to define vitamin D
deficiency. In addition, body mass index (BMI), milk intake,
participation in organized sports and total physical activity all
emerged as major determinants of vitamin D status. The relationship
between vitamin D status and bone mass and bone biomarkers showed
that girl participants with a higher vitamin D status had
significantly higher bone mass at the total body and distal and
proximal forearm, and higher concentrations of IGF-I, lower
concentrations of BAP and a lower urine Dpd/creatinine ratio
compared to those of poor vitamin D status. Therefore, continuous
participation in high physical activity, and adequate vitamin D
status throughout childhood and late adolescence could help achieve
maximum peak bone mass at maturity and thus reduce the risk of
osteoporotic fractures later in life.
Lap Lambert Academic Publishing
|Country of origin:
Leng Huat Foo
||229 x 152 x 5mm (L x W x T)
||Paperback - Trade
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