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Barriers and Channels Formed by Tight Junction Proteins II (Paperback) Loot Price: R969
Discovery Miles 9 690
You Save: R390 (29%)
Barriers and Channels Formed by Tight Junction Proteins II (Paperback): Michael Fromm, Jorg-Dieter Schulzke
Barriers and Channels Formed by Tight Junction Proteins II (Paperback): Michael Fromm, Jorg-Dieter Schulzke

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Barriers and Channels Formed by Tight Junction Proteins II (Paperback)

Michael Fromm, Jorg-Dieter Schulzke

Series: Annals of the New York Academy of Sciences

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List price R1,359 Loot Price R969 Discovery Miles 9 690 | Repayment Terms: R90 pm x 12* You Save R390 (29%)

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Tight junction proteins connect epithelial and endothelial cells and, importantly, form selective barriers and channels for paracellular transportation. Two types of tight junction proteins--the claudin family (claudins-1 to -27) and the TAMP family (occludin, Marvel-D2, and tricellulin)--can be distinguished molecularly and functionally. Recent work has focused on delineating the functional significance of differences in selective permeability, for example, by examining the regulatory mechanisms of tight junctions. This work is of great clinical importance as many inflammatory or infectious diseases are characterized by increased permeability and the manipulation of tight junctions presents a new horizon in the development of novel therapeutics. The volume "Barriers and Channels Formed by Tight Junction Proteins II "provides a detailed look at the recent advances in our understanding of tight junction regulation and dysregulation. The papers included focus on three major themes: inflammation and gastrointestinal function; epithelial transport, barrier modulation, and food components; and tight junctions in intestinal and renal epithelia.

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General

Imprint: New York Academy of Sciences
Country of origin: United States
Series: Annals of the New York Academy of Sciences
Release date: August 2012
First published: July 2012
Editors: Michael Fromm • Jorg-Dieter Schulzke
Dimensions: 251 x 176 x 9mm (L x W x T)
Format: Paperback
Pages: 192
ISBN-13: 978-1-57331-892-1
Barcode: 9781573318921
Categories: Promotions
Books > Science & Mathematics > Biology, life sciences > Cellular biology
Books > Science & Mathematics > Biology, life sciences > Cellular biology > General
LSN: 1-57331-892-2

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