Publications Volume 1-7 (Paperback)

This historic book may have numerous typos and missing text. Purchasers can download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1904 Excerpt: ... and almost constantly present. Voges says that one-half to two-thirds of these. animals when inoculated with mal de caderas die of the disease, the duration in those which finally succumb being from two to five months. He has some guinea pigs that have been alive for a year, have grown fat, and have had young. The generative power of the male suffers from the infection more than does that of the female. We have succeeded, as did Laveran and Mesnil, in producing a slight infection with Tr. lewisii, but it is always transient and devoid of symptoms. Guinea pigs do not naturally contract any form of Trypanosomiasis in this country, but when inoculated with the Trypanosoma of the present epidemic always show a long chronic infection. As nearly as can be determined, the incubation period varies from two to eleven days. The duration of the disease is from one to four months, and but few animals recover from it. The appearance of parasites in the circulating blood is very intermittent, not always in sufficient numbers for microscopic diagnosis, although the blood is constantly infectious by animal experiment. Sometimes parasites are not found by the usual microscopic technique for days and even weeks. The temperature curve (see fig. 145) is very irregular, more so than in any other class of animal with which we have worked. The symptoms in general resemble those of the rabbit. Edema of the genitals is marked, but in the rest of the body is less prominent than in the case of other animals. Anemia and emaciation develop slowly, but reach an extreme degree before death. The hair falls out in places, and small ulcers may appear on the belly and prepuce or vulva. Partial paralysis of the hind parts occurs but is not constant, being absent in some cases while well mark...