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Books > Medicine > Clinical & internal medicine > Neurology & clinical neurophysiology

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Metal-Based Neurodegeneration - from Molecular Mechanisms to Therapeutic Strategies (Hardcover, 2nd Revised edition) Loot Price: R2,585 Discovery Miles 25 850 You Save: R684 (21%)
Metal-Based Neurodegeneration - from Molecular Mechanisms to Therapeutic Strategies (Hardcover, 2nd Revised edition): Robert...
Metal-Based Neurodegeneration - from Molecular Mechanisms to Therapeutic Strategies (Hardcover, 2nd Revised edition): Robert...

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Metal-Based Neurodegeneration - from Molecular Mechanisms to Therapeutic Strategies (Hardcover, 2nd Revised edition)

Robert Crichton, Robert A Ward

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List price R3,269 Loot Price R2,585 Discovery Miles 25 850 You Save R684 (21%)

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Neurodegenerative diseases of the human brain appear in various forms, resulting in disorders of movement and coordination, cognitive deterioration and psychiatric disturbances. Many of the key factors leading to neurodegenerative diseases are similar, including the dysfunction of metal ion homeostasis, redox-active metal ions generating oxidative stress, and intracellular inclusion bodies.

"Metal-based Neurodegeneration" presents a detailed survey of the molecular origins of neurodegenerative diseases. Each chapter is dedicated to a specific disease, presenting the latest scientific findings, including details of their biochemical actors (proteins or peptides), their normal and pathological conformations, and a description of the diseases characteristics, with an emphasis on the role of metal-induced oxidative stress, which can result in the production of intracellular aggregates of target proteins and peptides.

Topics covered include: Brain function, physiology and the blood-brain barrierImmune system and neuroinflammationAging and mild cognitive impairment, MCIParkinson's DiseaseAlzheimer's DiseaseCreutzfelt-Jakob and related prion diseasesAlcoholic Brain DamageTherapeutic strategies to combat the onset and progression of neurological diseases

This extensively updated, full colour, second edition of "Metal-based Neurodegeneration" is an essential text for research scientists and clinicians working in gerontology, neuropathology, neurochemistry, and metalloprotein mechanisms.

General

Imprint: John Wiley & Sons
Country of origin: United States
Release date: November 2013
First published: November 2013
Authors: Robert Crichton • Robert A Ward
Dimensions: 254 x 178 x 27mm (L x W x T)
Format: Hardcover
Pages: 438
Edition: 2nd Revised edition
ISBN-13: 978-1-119-97714-8
Barcode: 9781119977148
Categories: Promotions
Books > Science & Mathematics > Chemistry
Books > Science & Mathematics > Chemistry > General
Books > Medicine > Clinical & internal medicine > Neurology & clinical neurophysiology
LSN: 1-119-97714-2

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