Neurodegenerative diseases of the human brain appear in various
forms, resulting in disorders of movement and coordination,
cognitive deterioration and psychiatric disturbances. Many of the
key factors leading to neurodegenerative diseases are similar,
including the dysfunction of metal ion homeostasis, redox-active
metal ions generating oxidative stress, and intracellular inclusion
"Metal-based Neurodegeneration" presents a detailed survey of
the molecular origins of neurodegenerative diseases. Each chapter
is dedicated to a specific disease, presenting the latest
scientific findings, including details of their biochemical actors
(proteins or peptides), their normal and pathological
conformations, and a description of the diseases characteristics,
with an emphasis on the role of metal-induced oxidative stress,
which can result in the production of intracellular aggregates of
target proteins and peptides.
Topics covered include: Brain function, physiology and the
blood-brain barrierImmune system and neuroinflammationAging and
mild cognitive impairment, MCIParkinson's DiseaseAlzheimer's
DiseaseCreutzfelt-Jakob and related prion diseasesAlcoholic Brain
DamageTherapeutic strategies to combat the onset and progression of
This extensively updated, full colour, second edition of
"Metal-based Neurodegeneration" is an essential text for research
scientists and clinicians working in gerontology, neuropathology,
neurochemistry, and metalloprotein mechanisms.
Is the information for this product incomplete, wrong or inappropriate?
Let us know about it.
Does this product have an incorrect or missing image?
Send us a new image.
Is this product missing categories?
Add more categories.
Review This Product
No reviews yet - be the first to create one!