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Biological Reactive Intermediates - Basic Mechanistic Research in Toxicology and Human Risk Assessment (Hardcover, 1996 ed.) Loot Price: R4,809
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You Save: R295 (6%)
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Biological Reactive Intermediates - Basic Mechanistic Research in Toxicology and Human Risk Assessment (Hardcover, 1996 ed.):...
Biological Reactive Intermediates - Basic Mechanistic Research in Toxicology and Human Risk Assessment (Hardcover, 1996 ed.):...

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Biological Reactive Intermediates - Basic Mechanistic Research in Toxicology and Human Risk Assessment (Hardcover, 1996 ed.)

Robert Snyder, James J. Kocsis, I.Glenn Sipes, George F. Kalf, David J. Jollow, Helmut Greim, Terrence J. Monks, Charlotte M. Witmer

Series: Advances in Experimental Medicine and Biology, v. 387

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List price R5,104 Loot Price R4,809 Discovery Miles 48 090 | Repayment Terms: R447 pm x 12* You Save R295 (6%)

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Much of organic chemistry is based on the ability of suitably structured chemicals to bind together through the formation of covalent bonds. Biochemistry is replete with exam- ples of enzymatically catalyzed reactions in which normal body constituents can be linked through covalent bonds during the process of intermediary metabolism. The finding that xenobiotic chemicals that enter the body from the environment, are metabolized to highly reactive species, and then covalently react with cellular macromolecules to induce toxic and carcinogenic effects was an observation that spawned the research featured in the Fifth International Symposium on Biological Reactive Intermediates (BRI V). The group of investigators that became fascinated with this process and its signifi- cance in terms of human health began their discussions in Turku, Finland (J 975), and continued them at Guildford, England (1980), College Park, Maryland (1985), Tucson, Arizona (1990), and Munich, Germany (1995). Among the results were a series of reports listed below, as well as the book for which this serves as the Preface. * Jollow, DJ., Kocsis, J.J., Snyder, R. and Vainio, H. (eds), Biological Reactive Intermediates: Formation, Toxicity and Inactivation, Plenum Press, NY, 1975. * Snyder, R., Park, D.V., Kocsis, J.J., Jollow, D.V., Gibson, G.G. and Witmer, C.M. (eds), Biological Reactive Intermediates II: Chemical Mechanisms and Biological Effects, Plenum Press, N.Y., 1982.

General

Imprint: Plenum Publishing Co.,N.Y.
Country of origin: United States
Series: Advances in Experimental Medicine and Biology, v. 387
Release date: June 1996
First published: 1996
Editors: Robert Snyder • James J. Kocsis • I.Glenn Sipes • George F. Kalf • David J. Jollow • Helmut Greim • Terrence J. Monks • Charlotte M. Witmer
Dimensions: 234 x 156 x 28mm (L x W x T)
Format: Hardcover
Pages: 462
Edition: 1996 ed.
ISBN-13: 978-0-306-45197-3
Barcode: 9780306451973
Categories: Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology
Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General
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Books > Science & Mathematics > Biology, life sciences
Books > Science & Mathematics > Biology, life sciences > General
LSN: 0-306-45197-2

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