DNA Modifications in the Brain: Neuroepigenetic Regulation of Gene
Expression begins with an historical overview of the early
discoveries surrounding DNA methylation in the mammalian brain and
then explores the evidence supporting a role for this epigenetic
mechanism in controlling gene expression programs across the
lifespan in both normal and diseased states. Chapters describe new
directions and technological advances, and provide an overview of
what the future holds for this exciting new field. This book is
ideal for medical, graduate and advanced undergraduate students,
but is also a great resource for researchers who need a broad
introduction to the dynamic nature of DNA that sheds light on
evolving concepts of gene-environment interaction and their effects
on adaptation and neuropsychiatric disease.
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