Aspirin is the most commonly prescribed drug and the most cost
effective therapy. However treatment failure has been of great
concern in clinical practice. In the laboratory, assessment of
platelet responsiveness to aspirin is not required routinely but
due to some clinical reasons the test is indicated. It is important
for the laboratory to have the appropriate procedure to perform the
test as well as to interpret the results. Whole blood platelet
aggregation method with conventional platelet aggregometer is able
to detect the aspirin resistance state and it is less laborious
than using platelet rich plasma. Three different methods to detect
this resistance state were compared and elaborated clearly in this
book. The findings from this study are reliable as the comparison
included the reference method. This book is suitable as a reference
to the pathologists, hematologists, laboratory scientists and
laboratory technologists working in clinical diagnostic laboratory
dealing with coagulation and hemostatic tests.
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