The resistance of malaria parasites to widely used drugs prompted
an upsurge in the development of new drugs with novel mechanism of
action, and re- evaluation of the existing drugs to overcome the
resistance problem. A number of new potential target pathways have
already been identified and efforts to develop lead compounds for
these putative targets hopefully will allow treatment of malaria
infections in a uniform sustained way. Considerable research
efforts were directed in the areas of chloroquine drug resistance
reversal agents. Careful development of some bisquinolines, which
are free of toxic side effect, 4-anilinoquinolines and modified
chloroquine analogs may be helpful to obtain drug candidates that
inhibit the growth of chloroquine sensitive and resistant
parasites. In the past several years, new structural classes of
antimalarial agents, target based antimalarial agents, iron
chelators have made some interesting and promising lead molecules
available for further optimization to provide compounds for
Is the information for this product incomplete, wrong or inappropriate?
Let us know about it.
Does this product have an incorrect or missing image?
Send us a new image.
Is this product missing categories?
Add more categories.
Review This Product
No reviews yet - be the first to create one!