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Books > Academic & Education > Professional & Technical > Biochemistry

Handbook of Stem Cells (Hardcover, 2nd edition): Anthony Atala, Robert Lanza Handbook of Stem Cells (Hardcover, 2nd edition)
Anthony Atala, Robert Lanza
R7,534 R6,337 Discovery Miles 63 370 Save R1,197 (16%) Within 8 - 15 working days

New discoveries in the field of stem cells increasingly dominate the news and scientific literature revealing an avalanche of new knowledge and research tools that are producing therapies for cancer, heart disease, diabetes, and a wide variety of other diseases that afflict humanity. The Handbook of Stem Cells integrates this exciting area of life science, combining in two volumes the requisites for a general understanding of adult and embryonic stem cells. Organized in two volumes entitled Pluripotent Stem Cells & Cell Biology and Adult & Fetal Stem Cells, this work contains contributions from the world s experts in stem cell research to provide a description of the tools, methods, and experimental protocols needed to study and characterize stem cells and progenitor populations as well as a the latest information of what is known about each specific organ system.
* Provides comprehensive coverage on this highly topical subject
* Contains contributions by the foremost authorities and premiere names in the field of stem cell research
*Companion website - http: //booksite.elsevier.com/9780123859426/- containsover 250 color figures in presentation format"

Molecular Biology Techniques - A Classroom Laboratory Manual (Paperback, 3rd edition): Heather Miller, D. Scott Witherow, Sue... Molecular Biology Techniques - A Classroom Laboratory Manual (Paperback, 3rd edition)
Heather Miller, D. Scott Witherow, Sue Carson
R1,751 R1,642 Discovery Miles 16 420 Save R109 (6%) Within 8 - 15 working days

This manual is an indispensable tool for introducing advanced undergraduates and beginning graduate students to the techniques of recombinant DNA technology, or gene cloning and expression. The techniques used in basic research and biotechnology laboratories are covered in detail. Students gain hands-on experience from start to finish in subcloning a gene into an expression vector, through purification of the recombinant protein.
The second edition has been completely re-written, with new laboratory exercises and all new illustrations and text, designed for a typical 15-week semester, rather than a 4-week intensive course. The project approach to experiments was maintained: students still follow a cloning project through to completion, culminating in the purification of recombinant protein. It takes advantage of the enhanced green fluorescent protein-students can actually visualize positive clones following IPTG induction.
*Cover basic concepts and techniques used in molecular biology research labs
*Student-tested labs proven successful in a real classroom laboratories
*Exercises simulate a cloning project that would be performed in a real research lab
*"Project" approach to experiments gives students an overview of the entire process
*Prep-list appendix contains necessary recipes and catalog numbers, providing staff with detailed instructions"

Pediatric Bone - Biology and Diseases (Hardcover, 2nd edition): Pediatric Bone - Biology and Diseases (Hardcover, 2nd edition)
R3,390 R2,812 Discovery Miles 28 120 Save R578 (17%) Within 8 - 15 working days

The second edition of this classic reference deals exclusively with the biology and diseases of bone as they affect children. Rapid advances have been made in our understanding of the mechanisms and factors controlling the growth and development of bone, and these are discussed in detail in this book. Further, the various diseases of bone that are peculiar to children are highlighted and discussed in the light of our current knowledge with regard to causation, clinical signs and treatment. The book is aimed to provide those clinicians interested in children's diseases and basic scientists with a comprehensive resource covering the various aspects of bone health and disease in children.
Key Features
* Deals exclusively with bone development and diseases of children and each chapter written by an
* Fully referenced providing an appendix of usually difficult to find information on the investigation of pediatric bone disease and reference values
* Covers both the physiology of bone and mineral homeostasis in children and diseases in one book
* Includes a CD-ROM of images

The Dictionary of Cell and Molecular Biology (Paperback, 5th edition): John M Lackie The Dictionary of Cell and Molecular Biology (Paperback, 5th edition)
John M Lackie
R1,431 R1,218 Discovery Miles 12 180 Save R213 (15%) Within 8 - 15 working days

An expanded, up-to-date resource for students and researchers, "The Dictionary of Cell & Molecular Biology, Fifth Edition," provides clear and concise definitions needed for laboratory study. With over 12,000 entries and a breadth of terms across bioscience, including plant molecular biology, microbiology and biotechnology, this revision reflects the changes in the research over the past few years. The latest edition of "The Dictionary of Cell and Molecular Biology" maintains its outstanding reputation as an authoritative, clear, and accessible reference with short, cross-referenced definitions of important technical terminology.
Thoroughly revised and expanded by over 20% with over 12,000 entries in cellular and molecular biologyIncludes expanded coverage of terms, including plant molecular biology, microbiology and biotechnology areasConsistently provides the most complete short definitions of technical terminology for anyone working in life sciences todayFeatures extensive cross-references Provides multiple definitions, notes on word origins, and other useful features

Protein NMR Spectroscopy - Principles and Practice (Hardcover, 2nd edition): John Cavanagh Protein NMR Spectroscopy - Principles and Practice (Hardcover, 2nd edition)
John Cavanagh
R2,172 R1,812 Discovery Miles 18 120 Save R360 (17%) Within 8 - 15 working days

Protein NMR Spectroscopy combines a comprehensive theoretical treatment of NMR spectroscopy with an extensive exposition of the experimental techniques applicable to proteins and other biological macromolecules in solution. Beginning with simple theoretical models and experimental techniques, Protein NMR Spectroscopy develops the complete repertoire of theoretical principles and experimental techniques necessary for understanding and implementing the most sophisticated NMR experiments.
Important new techniques and applications of NMR spectroscopy have emerged since the first edition of this extremely successful book was published in 1996. The second edition includes new sections describing measurement and use of residual dipolar coupling constants for structure determination, TROSY and deuterium labeling for application to large macromolecules, and experimental techniques for characterizing conformational dynamics. In addition, the treatments of instrumentation and signal acquisition, field gradients, multidimensional spectroscopy, and structure calculation are updated and enhanced.
Protein NMR Spectroscopy is written as a graduate-level textbook and will be of interest to biochemists, chemists, biophysicists, and structural biologists who utilize NMR spectroscopy or who wish to understand the latest developments in this field.
. Provides an understanding of the theoretical principles important for biological NMR spectroscopy
. Demonstrates how to implement, optimize and troubleshoot modern multi-dimensional NMR experiments
. Allows for the capability of designing effective experimental protocols for investigations of protein structures and dynamics
. Includes a comprehensive set of example NMR spectra of ubiquitin provides a reference for validation of experimental methods"

Designing Science Presentations - A Visual Guide to Figures, Papers, Slides, Posters, and More (Paperback): Matt Carter Designing Science Presentations - A Visual Guide to Figures, Papers, Slides, Posters, and More (Paperback)
Matt Carter
R931 R783 Discovery Miles 7 830 Save R148 (16%) Within 8 - 15 working days

"Designing Science Presentations "guides researchers and graduate students of virtually any discipline in the creation of compelling science communication. Most scientists never receive formal training in the creation, delivery, and evaluation of such material, yet it is essential for publishing in high-quality journals, soliciting funding, attracting lab personnel, and advancing a career.

This clear, readable volume fills that gap and provides visually intensive guidance at every step-from the construction of original figures to the presentation and delivery of those figures in papers, slideshows, posters, and websites. It provides pragmatic advice on the preparation and delivery of exceptional scientific presentations; demonstrates hundreds of visually striking presentation techniques, giving readers inspiration for creating their own; and is structured so that readers can easily find answers to particular questions.
Clear heading for each section indicates its message, highlighted with graphic illustrations Two summary paragraphs that complement the visual images and clearly discuss the main pointNumerous examples of high-quality figures, page layouts, slides, posters, and web pages to help stimulate readers' ideas for their own presentationsNumerous "before and after" examples to illustrate the contrast between poor and outstanding presentations

Food Texture and Viscosity - Concept and Measurement (Hardcover, 2nd edition): Malcolm Bourne Food Texture and Viscosity - Concept and Measurement (Hardcover, 2nd edition)
Malcolm Bourne
R2,495 R2,331 Discovery Miles 23 310 Save R164 (7%) Within 8 - 15 working days

Drawing together literature from a variety of fields, Food Texture and Viscosity, 2E, includes a brief history of this area and its basic principles. It reviews how texture and viscosity are measured, including the physical interactions between the human body and food, objective methods of texture measurements, the latest advances in texture-measuring instruments, various types of liquid flow, and more.
This revised edition contains approximately 30% new material, including two new chapters on physics and texture and the correlation between physical measurements and sensory assessments. It now includes two-color illustrations and includes a current list of equipment suppliers.

* Completely revised with approximately 30% new material
* Includes two new chapters on physics and texture and the correlation between physical measurements and sensory assessments
* Provides a list of suppliers of texture-measuring equipment
* Features two-color illustrations and text throughout
* Written by an award-winning author

Nitric Oxide - Biology and Pathobiology (Hardcover, 2nd edition): Louis J. Ignarro Nitric Oxide - Biology and Pathobiology (Hardcover, 2nd edition)
Louis J. Ignarro
R5,030 Discovery Miles 50 300 Within 7 - 11 working days

Nitric oxide (NO) is a gas naturally found in the body that conveys information between cells. In the last decade researchers have found that NO is a signaling molecule of key importance for the cardiovascular system, regulating blood pressure and blood flow to different organs. In addition, discoveries surrounding nitric oxide s role as a principal neurotransmitter moderating erectile function, a pathophysiological negotiator and messenger in inflammation, and a weapon against infections have increased research attention across the fields of biochemistry, chemistry, molecular biology, gene therapy, cell biology, immunology, pharmacology, neuroscience, and physiology.
Edited by Nobel Laureate Louis J. Ignarro

Up-to-date therapeutic implications of nitric oxide research Authored by world experts on nitric oxide Detailed research of the biochemistry and synthesis of nitric oxide

Clinical and Translational Science - Principles of Human Research (Paperback): David Robertson, Gordon H. Williams Clinical and Translational Science - Principles of Human Research (Paperback)
David Robertson, Gordon H. Williams
R2,364 Discovery Miles 23 640 Within 7 - 11 working days

Clinical or translational science is the field of study devoted to investigating human health and disease, interventions and outcomes for the purposes of developing new treatment approaches, devices, and modalities to improve health. New molecular tools and diagnostic technologies based on clinical and translational research have lead to a better understanding of human disease and the application of new therapeutics for enhanced health.
This book is designed as the most authoritative and modern resource for the broad range of investigators in various medical specialties taking on the challenge of clinical research. Prepared with an international perspective, this resource begins with experimental design and investigative tools to set the scene for readers. It then moves on to human genetics and pharmacology with a focus on statistics, epidemiology, genomic information, drug discovery and development, and clinical trials. Finally, it turns to legal, social, and ethical issues of clinical research concluding with a discussion of future prospects to provide readers with a comprehensive view of the this developing area of science.
* Clinical research is one of the fastest growing fields in private practice and academic medicine with practical biological, physiological, cellular, and therapeutic applications
* Contributions from international leaders provide insight into background and future understanding for clinical and translational science
* Provides the structure for complete instruction and guidance on the subject from fundamental principles, approaches and infrastructure to human genetics, human pharmacology, research in special populations, the societal context ofhuman research, and the future of human research

BioIndustry Ethics (Paperback): david l Finegold, Cecile Bensimon, Abdallah S. Daar, Margaret L. Eaton, Beatrice Godard, Bartha... BioIndustry Ethics (Paperback)
david l Finegold, Cecile Bensimon, Abdallah S. Daar, Margaret L. Eaton, Beatrice Godard, …
R1,183 Discovery Miles 11 830 Within 7 - 11 working days

This book is the first systematic, detailed treatment of the approaches to ethical issues taken by biotech and pharmaceutical companies. The application of genetic/genomic technologies raises a whole spectrum of ethical questions affecting global health that must be addressed. Topics covered in this comprehensive survey include considerations for bioprospecting in transgenics, genomics, drug discovery, and nutrigenomics, as well as how to improve stakeholder relations, design ethical clinical trials, avoid conflicts of interest, and establish ethics advisory boards. The expert authors represent multiple disciplines including law, medicine, bioinformatics, pharmaceutics, business, and ethics.

Functioning of Transmembrane Receptors in Signaling Mechanisms - Cell Signaling Collection (Paperback): Functioning of Transmembrane Receptors in Signaling Mechanisms - Cell Signaling Collection (Paperback)
R1,304 R1,121 Discovery Miles 11 210 Save R183 (14%) Within 8 - 15 working days

A primary component of cell signaling research, this title covers the principal membrane-bound receptor families, including their structural organization. Written and edited by experts in the field, this book provides up-to-date research on transmembrane signaling entities and their initiating responses following extracellular stimulation.

Articles written and edited by experts in the field
Thematic volume covering effectors, cytosolic events, nuclear, and cytoplasmic events
Up-to-date research on signaling systems and mutations in transcription factors that provide new targets for treating disease

Peptide and Protein Delivery (Hardcover): Chris Van der Walle Peptide and Protein Delivery (Hardcover)
Chris Van der Walle
R2,403 R1,980 Discovery Miles 19 800 Save R423 (18%) Within 8 - 15 working days

The growing area of peptide and protein therapeutics research is of paramount importance to medical application and advancement. A needed reference for entry level researchers and researchers working in interdisciplinary / collaborative projects, Peptide and Protein Delivery addresses the current and emerging routes for delivery of therapeutics. Covering cerebral delivery, pulmonary delivery, transdermal delivery, intestinal delivery, ocular delivery, parenteral delivery, and nasal delivery, this resource offers an overview of the main routes in therapeutics. Researchers across biochemistry, pharmaceutical, molecular biology, cell biology, immunology, chemistry and biotechnology fields will find this publication invaluable for peptide and protein laboratory research.
Discusses the most recent data, ideas and conceptsPresents case studies and an industrial perspectiveDetails information from the molecular level to bioprocessingThought provoking, for the novice to the specialistTimely, for today's biopharmaceuticals market

Regulation of Organelle and Cell Compartment Signaling - Cell Signaling Collection (Paperback): Regulation of Organelle and Cell Compartment Signaling - Cell Signaling Collection (Paperback)
R1,321 R1,143 Discovery Miles 11 430 Save R178 (13%) Within 8 - 15 working days

This must-have cell signaling title will appeal to researchers across molecular biology, biochemistry, cell biology and genetics. The articles are written and edited by experts in the field and emphasize signaling to and from intracellular compartments including transcriptional responses to cytoplasmic and nuclear signaling events, chromatin remodeling and stress responses, the regulation of endoplasmic reticulum function, control of cell cycle progression and apoptosis and the modulation of the activities of mitochondria and other organelles.

Articles written and edited by experts in the field
Thematic volume covering regulation of endoplasmic reticulum function, regulation of cell cycle progression, and quality control and assurance in mitochondrion events
Up-to-date research on events in membrane proteins and proteins of intracellular matrix

Principles and Practice of Clinical Research (Hardcover, 3rd edition): John I. Gallin, Frederick P. Ognibene Principles and Practice of Clinical Research (Hardcover, 3rd edition)
John I. Gallin, Frederick P. Ognibene
R2,691 Discovery Miles 26 910 Within 7 - 11 working days

The third edition of this innovative work again provides a unique perspective on the clinical discovery process by providing input from experts within the NIH on the principles and practice of clinical research. Molecular medicine, genomics, and proteomics have opened vast opportunities for translation of basic science observations to the bedside through clinical research. As an introductory reference it gives clinical investigators in all fields an awareness of the tools required to ensure research protocols are well designed and comply with the rigorous regulatory requirements necessary to maximize the safety of research subjects. Complete with sections on the history of clinical research and ethics, copious figures and charts, and sample documents it serves as an excellent companion text for any course on clinical research and as a must-have reference for seasoned researchers.
Incorporates new chapters on Managing Conflicts of Interest in Human Subjects Research, Clinical Research from the Patient's Perspective, The Clinical Researcher and the Media, Data Management in Clinical Research, Evaluation of a Protocol Budget, Clinical Research from the Industry Perspective, and Genetics in Clinical ResearchAddresses the vast opportunities for translation of basic science observations to the bedside through clinical researchDelves into data management and addresses how to collect data and use it for discoveryContains valuable, up-to-date information on how to obtain funding from the federal government

Growth Factors and Their Receptors in Cell Differentiation, Cancer and Cancer Therapy (Hardcover): G V Sherbert Growth Factors and Their Receptors in Cell Differentiation, Cancer and Cancer Therapy (Hardcover)
G V Sherbert
R2,757 R2,613 Discovery Miles 26 130 Save R144 (5%) Within 8 - 13 working days

Recent years have seen a considerable emphasis on growth factors and the elucidation of their mode of function, which has led to the recognition that growth factors, their receptors as well as downstream elements of signalling associated with their function might be potential targets in therapeutic management of human diseases. Humanised monoclonal antibodies raised against growth factor receptors have proved to be valuable for targeted cancer treatment and in patient management.

This book reviews the latest developments providing insights into the signalling processes involved in morphogenesis and pathogenesis with emphasis on using the elements of the signalling cascades as targets for therapeutic deployment.

Provides afundamental understanding of the basic functions of growth factors and their receptors, describing how they are linked in biological processes

Aids the development of therapeutic treatments for cancer

Focuses on the interrelationships and convergence of growth factors and their receptors in development and pathogenesis and encourages greater cooperation and integration in the areas of developmental, cancer and cancer therapeutic research "

Stories of Success, Volume 46 - Stories of Success Personal Recollections: v. 11 (Hardcover): Stories of Success, Volume 46 - Stories of Success Personal Recollections: v. 11 (Hardcover)
R3,849 Discovery Miles 38 490 Within 7 - 11 working days

This book is the latest volume in the highly successful series "Comprehensive Biochemistry." It provides a historical and autobiographical perspective of the developments in the field through the contributions of leading individuals who reflect on their careers and their impact on biochemistry. Volume 46 is essential reading for everyone from graduate student to professor, placing in context major advances not only in biochemical terms but in relation to historical and social developments. Readers will be delighted by the lively style and the insight into the lives and careers of leading scientists of their time.
* Contributors are distinguished scientists in the field
* Unique series of personal recollections
* Presents scientific research in a historical perspective

Handbook of Evaluation Methods for Health Informatics (Paperback): Jytte Brender McNair Handbook of Evaluation Methods for Health Informatics (Paperback)
Jytte Brender McNair
R2,158 Discovery Miles 21 580 Within 7 - 11 working days

This Handbook provides a complete compendium of methods for evaluation of IT-based systems and solutions within healthcare. Emphasis is entirely on assessment of the IT-system within its organizational environment. The author provides a coherent and complete assessment of methods addressing interactions with and effects of technology at the organizational, psychological, and social levels.
It offers an explanation of the terminology and theoretical foundations underlying the methodological analysis presented here. The author carefully guides the reader through the process of identifying relevant methods corresponding to specific information needs and conditions for carrying out the evaluation study. The Handbook takes a critical view by focusing on assumptions for application, tacit built-in perspectives of the methods as well as their perils and pitfalls.
*Collects a number of evaluation methods of medical informatics
*Addresses metrics and measures
*Includes an extensive list of anotated references, case studies, and a list of useful Web sites

Emergent Collective Properties, Networks and Information in Biology, Volume 40 (Hardcover, 40th edition): J. Ricard Emergent Collective Properties, Networks and Information in Biology, Volume 40 (Hardcover, 40th edition)
J. Ricard; Series edited by Giorgio Bernardi
R3,826 Discovery Miles 38 260 Within 7 - 11 working days

The concept of network as a mathematical description of a set of states, or events, linked according to a certain topology has been developed recently and has led to a novel approach of real world. This approach is no doubt important in the field of biology. In fact biological systems can be considered networks. Thus, for instance, an enzyme-catalysed reaction is a network that links, according to a certain topology, the various states of the protein and of its complexes with the substrates and products of the chemical reaction. Connections between neurons, social relations in animal and human populations are also examples of networks. Hence there is little doubt that the concept of network transgresses the boundaries between traditional scientific disciplines.
This book is aimed at discussing in physical terms these exciting new topics on simple protein model lattices, supramolecular protein edifices, multienzyme and gene networks.
*Physical and mathematical approach of biological phenomena.
*Offers biochemists and biologists the mathematical background required to understand the text.
*Associates in the same general formulation, the ideas of communication of a message and organization of a system.
*Provides a clear-cut definition and mathematical expression of the concepts of reduction, integration, emergence and complexity that were so far time-honoured and vague

Writing Clinical Research Protocols - Ethical Considerations (Paperback): Evan DeRenzo, Joel Moss Writing Clinical Research Protocols - Ethical Considerations (Paperback)
Evan DeRenzo, Joel Moss
R1,623 Discovery Miles 16 230 Within 7 - 11 working days

This highly engaging guide for clinical researchers provides a foundation for improving skills in the understanding of ethical requirements in the design and conduct of clinical research. It includes practical information on ethical principles in clinical research, designing appropriate research studies, writing consent and assent documents, getting protocols approved, special populations, confidentiality issues, and the reporting of adverse events. A valuable appendix includes a listing of web resources about research ethics as well as a glossary. This will be an invaluable resource for basic scientists collaborating in clinical trials, physician investigators, clinical research fellows, research nurse coordinators, residents, and anyone who wants a better understanding of the clinical trials process.
* Walks investigators and trainees through identification of the ethical aspects of each section of a clinical research protocol
* Includes a chapter containing Case Histories
* Contains information on conducting clinical research within the pharmaceutical industry
* An appendix includes internet resources and world wide web addresses for important research ethics documents and regulations
* Chapter on 'Study Design and Methodology' purposely expanded to explicitly address biostatistical considerations

Modeling: Gateway to the Unknown, Volume 1 - A Work by Rom Harre (Hardcover, New): Daniel Rothbart Modeling: Gateway to the Unknown, Volume 1 - A Work by Rom Harre (Hardcover, New)
Daniel Rothbart
R1,432 Discovery Miles 14 320 Within 7 - 11 working days

Edited by Daniel Rothbart of George Mason University in Virginia, this book is a collection of Rom Harre's work on modeling in science (particularly physics and psychology). In over 28 authored books and 240 articles and book chapters, Rom Harre of Georgetown University in Washington, DC is a towering figure in philosophy, linguistics, and social psychology. He has inspired a generation of scholars, both for the ways in which his research is carried out and his profound insights. For Harre, the stunning discoveries of research demand a kind of thinking that is found in the construction and control of models. Iconic modeling is pivotal for representing real-world structures, explaining phenomena, manipulating instruments, constructing theories, and acquiring data.
This volume in the new Elsevier book series Studies in Multidisciplinarity includes major topics on the structure and function of models, the debates over scientific realism, explanation through analogical modeling, a metaphysics for physics, the rationale for experimentation, and modeling in social encounters.
* A multidisciplinary work of sweeping scope about the nature of science
* Revolutionary interpretation that challenges conventional wisdom about the character of scientific thinking
* Profound insights about fundamental challenges to contemporary physics
* Brilliant discoveries into the nature of social interaction and human identity
* Presents a rational conception of methods for acquiring knowledge of remote regions of the world
* Written by one of the great thinkers of our time.

WTEC Panel Report on Tissue Engineering Research (Hardcover, New): Larry V. McIntire WTEC Panel Report on Tissue Engineering Research (Hardcover, New)
Larry V. McIntire
R3,816 Discovery Miles 38 160 Within 7 - 11 working days

WTEC Panel on Tissue Engineering Research is a comparative review of tissue engineering research and development activities in the United States, Japan, and Western Europe conducted by a panel of leading U.S. experts in the field. This book covers biomaterials, cells, biomolecules, non-medical applications, engineering design, informatics, and legal and regulatory issues associated with tissue engineering research and applications. This document will serve as a basis for continued dialogue within nations' tissue engineering research and development community and with other important stakeholders, providing guidance for future programs. This text highlights the necessity for providing continued and enhanced resources to further the progress in tissue engineering, harness developments, and maintain scientific and economic leadership.

Telomerase, Aging and Disease, Volume 8 (Hardcover, 1st ed): M.P. Mattson Telomerase, Aging and Disease, Volume 8 (Hardcover, 1st ed)
M.P. Mattson; Foreword by J.W. Shay, W.E. Wright
R2,827 Discovery Miles 28 270 Within 7 - 11 working days

This volume of "Advances in Cell Aging and Gerontology" critically reviews the rapidly advancing area of telomerase research with a focus at the molecular and cellular levels. The clearly established function of telomerase is to maintain chromosome ends during successive rounds of cell division by adding a six base DNA repeat on to the telomeric ends of chromosomes. As presented in the chapters of this volume, the mechanisms that regulate telomerase expression and activity are complex. Moreover, emerging data suggest additional roles for telomerase in the regulation of cell differentiation and survival.


It is expected that this quite comprehensive volume will provide a valuable resource for graduate students and postdocs in the telomerase field and for established investigators in other fields who are beginning to study telomerase in their particular research program. With an increasing number of proteins being brought into the fold of telomerase research (e.g., DNA damage and repair response proteins, heat-shock proteins, and proteins in various signal transduction cascades) many new scientists are beginning to study this enzyme from novel vantage points.

Interorganellar Signaling in Age-Related Disease, Volume 7 (Hardcover): M.P. Mattson Interorganellar Signaling in Age-Related Disease, Volume 7 (Hardcover)
M.P. Mattson
R2,670 Discovery Miles 26 700 Within 7 - 11 working days

Collectively, the chapters in this work will provide the reader with novel insight into the inter-relationships of the function of different organelles in the sequences of events that lead to cellular dysfunction and degeneration in the aging human population. The chapters are rich in information for cell and molecular biologists pursuing studies of the different diseases covered. In addition, the clinician will find value in understanding mechanisms underlying age-related disease as such an understanding will lead to novel therapeutic approaches for an array of age-related diseases.

Selected Topics in the History of Biochemistry: Personal Recollections VI, Volume 41 - Comprehensive Biochemistry (Hardcover):... Selected Topics in the History of Biochemistry: Personal Recollections VI, Volume 41 - Comprehensive Biochemistry (Hardcover)
R. Jaenicke, G. Semenza
R5,700 Discovery Miles 57 000 Within 7 - 11 working days

These volumes are of interest to bioscientists and to historians alike. Many authors, both as individuals and as scientists, lived and worked in the 'age of extremes' in the so-called 'short 20th century', and yet contributed significantly to the unprecedented development of life sciences in this period. These 'oral histories', set against a backdrop of the Second World War, Holocaust, and Stalinist terror, are thus of interest and relevance to older and younger generations alike. Perhaps the lessons learned from these first-hand accounts may contribute in some way to ensuring that future scientists can enjoy the fascination of science undisturbed by the avoidable tragedy of man-made events.


The contributors to this volume in the Comprehensive Biochemistry series encompass a wide variety of experiences in many different countries and in very different fields of biochemistry. Some have worked close to the laboratory bench throughout their scientific life and are continuing to do so. Others have been closely engaged in organizational matters, both nationally and internationally. All mention incidents in their own career or have observed those in others that will be of interest to future historians who will record and assess the period in which our contributors have lived and worked. It was an extremely exciting time for the life sciences. It was also a period of major and often tragic historical events that deeply affected the life and work of the generation to which our contributors belong.

Vital Forces - The Discovery of the Molecular Basis of Life (Hardcover): Graeme K. Hunter Vital Forces - The Discovery of the Molecular Basis of Life (Hardcover)
Graeme K. Hunter
R2,553 Discovery Miles 25 530 Within 7 - 11 working days

Vital Forces tells the history of the 'biochemical revolution', a period of unprecedentedly rapid advance in human knowledge that profoundly affected our view of life and laid the foundation for modern medicine and biotechnology. The story is told in a clear, engaging, and absorbing manner. This delightful work relates the fascinating and staggering advances in concepts and theories over the last 200 years and introduces the major figures of the times.
Vital Forces also describes the discovery of the molecular basis of life through the stories of the scientists involved, including such towering figures as Louis Pasteur, Gregor Mendel, Linus Pauling, and Francis Crick. Combining science and biography into a seamless chronological narrative, the author brings to life the successes and failures, collaborations and feuds, and errors and insights that produced the revolution in biology.
* Vividly describes dramatic scientific discoveries, personalities, feuds and rivalries
* Answers a general readers quest to understand the nature of life, and the relevance of biochemistry/molecular biology to modern medicine, industry and agriculture

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