Your cart is empty
Biomimetics is the idea of creating new technologies abstracted from what we find in biology. Ocean Innovation: Biomimetics Beneath the Waves seeks that technological inspiration from the rich biodiversity of marine organisms. Bringing both a biological and engineering perspective to the biomimetic potential of oceanic organisms, this richly illustrated book investigates questions such as: How can we mimic the sensory systems of sea creatures like sharks, sea turtles, and lobsters to improve our ability to navigate underwater? What can we do to afford humans the opportunity to go unnoticed by marine life? How can we diffuse oxygen from water to enable deep diving without the risk of decompression sickness? Each chapter explores an area where we, as divers and technologists, can benefit from understanding how animals survive in the sea, presenting case studies that demonstrate how natural solutions can be applied to mankind's engineering challenges.
Gain a strong foundation in the field of orthotics and prosthetics! Orthotics and Prosthetics in Rehabilitation, 4th Edition is a clear, comprehensive, one-stop resource for clinically relevant rehabilitation information and application. Divided into three sections, this text gives you a foundation in orthotics and prosthetics, clinical applications when working with typical and special populations, and an overview of amputation and prosthetic limbs. This edition has been updated with coverage of the latest technology and materials in the field, new evidence on effectiveness and efficacy of interventions and cognitive workload associated usage along with enhanced color photographs and case studies - it's a great resource for students and rehabilitation professionals alike. Comprehensive coverage addresses rehabilitation in a variety of environments, including acute care, long-term care and home health care, and outpatient settings. Book organized into three parts corresponding with typical patient problems and clinical decision-making. The latest evidence-based research throughout text help you learn clinical-decision making skills. Case studies present real-life scenarios that demonstrate how key concepts apply to clinical decision-making and evidence-based practice. World Health Organization disablement model (ICF) incorporated to help you learn how to match patient's limitations with the best clinical treatment. Multidisciplinary approach in a variety of settings demonstrates how physical therapists can work with the rest of the healthcare team to provide high quality care in orthotic/prosthetic rehabilitation. The latest equipment and technology throughout text addresses the latest options in prosthetics and orthotics rehabilitation Authoritative information from the Guide to Physical Therapist Practice, 2nd Edition is incorporated throughout. A wealth of tables and boxes highlight vital information for quick reference and ease of use. NEW! Color photographs improve visual appeal and facilitates learning. NEW! Increased evidence-based content includes updated citations; coverage of new technology such as microprocessors, microcontrollers, and integrated load cells; new evidence on the effectiveness and efficacy of interventions; and new evidence on cognitive workload usage. NEW! Authors Kevin K Chui, PT, DPT, PhD, GCS, OCS, CEEAA, FAAOMPT and Sheng-Che (Steven) Yen, PT, PhD add their expertise to an already impressive list of contributors.
Brain science is at the dawn of a new era-and the technologies emerging as a result could forever alter what it means to be human. Welcome to what tech pioneer and inventor Tan Le calls "the NeuroGeneration." It will blow your mind. The human brain is perhaps the most powerful and mysterious arrangement of matter in the known universe. New discoveries that unravel this mystery and let us tap into this power offer almost limitless potential-the ability to reshape ourselves and our thought processes, to improve our health and extend our lives, and to enhance and augment the ways we interact with the world around us. It may sound like the stuff of science fiction, but it is quickly becoming reality. In The NeuroGeneration, award-winning inventor Tan Le explores exciting advancements in brain science and neurotechnology that are revolutionizing the way we think, work, and heal. Join Le as she criss-crosses the globe, introducing the brilliant neurotech innovators and neuroscientists at the frontiers of brain enhancement. Along the way, she shares incredible stories from individuals whose lives are already being transformed by their inventions-an endurance racer paralyzed in a fall, who now walks thanks to neural stimulation and an exoskeleton; a man who drives a race car with his mind; even a color-blind "cyborg" whose brain implant allows him to "hear" colors. The NeuroGeneration reveals the dizzying array of emerging technologies-including cranial stimulation that makes you learn faster, an artificial hippocampus that restores lost memories, and neural implants that aim to help us keep up with or even outpace artificial intelligence-that promise to alter the brain in unprecedented ways, unlocking human potential we never dreamed possible. Le also explores how these futuristic innovations will impact our world, disrupt the way we do business, upend healthcare as we know it, and remake our lives in wondrous and unexpected ways. As fascinating as it is timely, The NeuroGeneration offers a thrilling glimpse of the future of our species, and how changing our brains can change human life as we know it.
With the constant evolution of implant technology, and improvement in the production of allograft and bone substitutes, the armamentarium of the orthopaedic surgeon has significantly expanded. In particular, the recent involvement of nanotechnologies opens up the possibilities of new approaches in the interactive interfaces of implants. With many important developments occurring since the first edition of this well-received book, this updated resource informs orthopaedic practitioners on a wide range of biomechanical advances in one complete reference guide. Biomechanics and Biomaterials in Orthopedics, 2nd edition compiles the most prominent work in the discipline to offer newly-qualified orthopedic surgeons a summary of the fundamental skills that they will need to apply in their day-to-day work, while also updating the knowledge of experienced surgeons. This book covers both basic concepts concerning biomaterials and biomechanics as well as their clinical application and the experience from everyday practical use. This book will be of great value to specialists in orthopedics and traumatology, while also providing an important basis for graduate and postgraduate learning.
A comprehensive text in the field of biomaterials science and tissue engineering, covering fundamental principles and methods related to processing-microstructure-property linkages as applied to biomaterials science. Essential concepts and techniques of the cell biology are discussed in detail, with a focus quantitatively and qualitatively evaluating cell-material interaction. It gives detailed discussion on the processing, structure and properties of metals, ceramics and polymers, together with techniques and guidelines. Comprehensive coverage of in vitro and in vivo biocompatibility property evaluation of materials for bone, neural as well as cardiovascular tissue engineering applications, together with representative protocols. Supported by several multiple-choice questions, fill in the blanks, review questions, numerical problems and solutions to selected problems, this is an ideal text for undergraduate and graduate students in understanding fundamental concepts and the latest developments in the field of biomaterials science.
Shows the newest developments in the field of multi-parametric model predictive control and optimization and their application for drug delivery systems This book is based on the Modelling, Control and Optimization of Biomedical Systems (MOBILE) project, which was created to derive intelligent computer model-based systems for optimization of biomedical drug delivery systems in the cases of diabetes, anaesthesia, and blood cancer. These systems can ensure reliable and fast calculation of the optimal drug dosage without the need for an online computer--while taking into account the specifics and constraints of the patient model, flexibility to adapt to changing patient characteristics and incorporation of the physician's performance criteria, and maintaining the safety of the patients. Modelling Optimization and Control of Biomedical Systems covers: mathematical modelling of drug delivery systems; model analysis, parameter estimation, and approximation; optimization and control; sensitivity analysis & model reduction; multi-parametric programming and model predictive control; estimation techniques; physiologically-based patient model; control design for volatile anaesthesia; multiparametric model based approach to intravenous anaesthesia; hybrid model predictive control strategies; Type I Diabetes Mellitus; in vitro and in silico block of the integrated platform for the study of leukaemia; chemotherapy treatment as a process systems application; and more. Introduces readers to the Modelling, Control and Optimization of Biomedical Systems (MOBILE) project Presents in detail the theoretical background, computational tools, and methods that are used in all the different biomedical systems Teaches the theory for multi-parametric mixed-integer programming and explicit optimal control of volatile anaesthesia Provides an overview of the framework for modelling, optimization, and control of biomedical systems This book will appeal to students, researchers, and scientists working on the modelling, control, and optimization of biomedical systems and to those involved in cancer treatment, anaesthsia, and drug delivery systems.
Thoroughly revised and updated for the second edition, this comprehensive textbook integrates basic and advanced concepts of mechanics with numerical methods and biomedical applications. Coverage is expanded to include a complete introduction to vector and tensor calculus, and new or fully updated chapters on biological materials and continuum mechanics, motion, deformation and rotation, and constitutive modelling of solids and fluids. Topics such as kinematics, equilibrium, and stresses and strains are also included, as well as the mechanical behaviour of fibres and the analysis of one-dimensional continuous elastic media. Numerical solution procedures based on the Finite Element Method are presented, with accompanying MATLAB-based software and dozens of new biomedical engineering examples and exercises allowing readers to practise and improve their skills. Solutions for instructors are also available online. This is the definitive guide for both undergraduate and graduate students taking courses in biomechanics.
An introduction to the field of applied ontology with examples derived particularly from biomedicine, covering theoretical components, design practices, and practical applications. In the era of "big data," science is increasingly information driven, and the potential for computers to store, manage, and integrate massive amounts of data has given rise to such new disciplinary fields as biomedical informatics. Applied ontology offers a strategy for the organization of scientific information in computer-tractable form, drawing on concepts not only from computer and information science but also from linguistics, logic, and philosophy. This book provides an introduction to the field of applied ontology that is of particular relevance to biomedicine, covering theoretical components of ontologies, best practices for ontology design, and examples of biomedical ontologies in use. After defining an ontology as a representation of the types of entities in a given domain, the book distinguishes between different kinds of ontologies and taxonomies, and shows how applied ontology draws on more traditional ideas from metaphysics. It presents the core features of the Basic Formal Ontology (BFO), now used by over one hundred ontology projects around the world, and offers examples of domain ontologies that utilize BFO. The book also describes Web Ontology Language (OWL), a common framework for Semantic Web technologies. Throughout, the book provides concrete recommendations for the design and construction of domain ontologies.
In this comprehensive work, experts in the field detail recent advances in medical and biological microwave sensors and systems, with chapters on topics such as implantable sensors, wearable microwave tags, and UWB technology. Each chapter explores the theory behind the technology, as well as its design and implementation. This is supported by practical examples and details of experimental results, along with discussion of system design, design trade-offs, and possible constraints and manufacturing issues. Applications described include intracranial pressure monitoring, vital signs monitoring, and non-invasive molecular and cellular investigations. Presenting new research and advances in the field, and focusing on the state of the art in medical and biological microwave sensors, this work is an invaluable resource for enthusiastic researchers and practicing engineers in the fields of electrical engineering, biomedical engineering, and medical physics.
This fully updated, self-contained textbook covering modern optical microscopy equips students with a solid understanding of the theory underlying a range of advanced techniques. Two new chapters cover pump-probe techniques, and imaging in scattering media, and additional material throughout covers light-sheet microscopy, image scanning microscopy, and much more. An array of practical techniques are discussed, from classical phase contrast and confocal microscopy, to holographic, structured illumination, multi-photon, and coherent Raman microscopy, and optical coherence tomography. Fundamental topics are also covered, including Fourier optics, partial coherence, 3D imaging theory, statistical optics, and the physics of scattering and fluorescence. With a wealth of end-of-chapter problems, and a solutions manual for instructors available online, this is an invaluable book for electrical engineering, biomedical engineering, and physics students taking graduate courses on optical microscopy, as well as advanced undergraduates, professionals, and researchers looking for an accessible introduction to the field.
Discusses the basic physical principles underlying Biomedical Photonics, spectroscopy and microscopy This volume discusses biomedical photonics, spectroscopy and microscopy, the basic physical principles underlying the technology and its applications. The topics discussed in this volume are: Biophotonics; Fluorescence and Phosphorescence; Medical Photonics; Microscopy; Nonlinear Optics; Ophthalmic Technology; Optical Tomography; Optofluidics; Photodynamic Therapy; Image Processing; Imaging Systems; Sensors; Single Molecule Detection; Futurology in Photonics. * Comprehensive and accessible coverage of the whole of modern photonics * Emphasizes processes and applications that specifically exploit photon attributes of light * Deals with the rapidly advancing area of modern optics * Chapters are written by top scientists in their field Written for the graduate level student in physical sciences; Industrial and academic researchers in photonics, graduate students in the area; College lecturers, educators, policymakers, consultants, Scientific and technical libraries, government laboratories, NIH.
This book provides a comprehensive review of the chemistry and research illustrating the benefits of polyurethane for immobilizing cells, with dozens of case studies in medical devices and environmental engineering. Offers an essential resource for medical and environmental scientists Provides a multidisciplinary and lucid writing style that uses little or no jargon Extrapolates current technology into advanced areas, especially environmental remediation and medical devices Fills the gap between immobilization research and practical applications
Peptides serve as effective drugs in the clinic today. However the inherent drawbacks of peptide structures can limit their efficacy as drugs. To overcome this researchers are developing new methods to create tailor-made' peptides and proteins with improved pharmacological properties. Design of Peptides and Proteins provides an overview of the experimental and computational methods for peptide and protein design, with an emphasis on specific applications for therapeutics and biomedical research. Topics covered include: * Computer modeling of peptides and proteins * Peptidomimetics * Design and synthesis of cyclic peptides * Carbohydrates in peptide and protein design * De novo design of peptides and proteins * Medical development applications * An extended case study - the design of insulin variants Design of Peptides and Proteins presents the state-of-the-art of this exciting approach for therapeutics, with contributions from international experts. It is an essential resource for academic and industrial scientists in the fields of peptide and protein drug design, biomedicine, biochemistry, biophysics, molecular modelling, synthetic organic chemistry and medicinal/pharmaceutical chemistry.
Atlas of Hematopathology: Morphology, Immunophenotype, Cytogenetics, and Molecular Approaches, Second Edition, will appeal to both a wide range of people undergoing training in a variety of medical fields and practicing non-hematopathologists. For clinicians, fellows and residents, correct diagnosis (and therefore correct treatment) of diseases depends on a strong understanding of the molecular basis for the disease, making this book a crucial resource. This atlas contains hundreds of high-quality color images that mirror the findings that fellows and clinicians encounter in practice. In addition, it provides information in a quick, simple and user-friendly manner, attracting both those in training and non- experts. Residents, fellows, practicing clinicians, and researchers in pathology, hematology and hematology/oncology will find this a useful resource.
Would you change your genes if you could? As we confront the 'industrial revolution of the genome', the recent discoveries of Crispr-Cas9 technologies are offering, for the first time, cheap and effective methods for editing the human genome. This opens up startling new opportunities as well as significant ethical uncertainty. Tracing events across a fifty-year period, from the first gene splicing techniques to the present day, this is the story of gene editing - the science, the impact and the potential. Kozubek weaves together the fascinating stories of many of the scientists involved in the development of gene editing technology. Along the way, he demystifies how the technology really works and provides vivid and thought-provoking reflections on the continuing ethical debate. This updated paperback edition contains all the very latest on the patent battle over Crisp and the applications of Crispr technology in agriculture and medicine.
Body area networks (BANs) are networks of wireless sensors and medical devices embedded in clothing, worn on or implanted in the body, and have the potential to revolutionize healthcare by enabling pervasive healthcare. However, due to their critical applications affecting human health, challenges arise when designing them to ensure they are safe for the user, sustainable without requiring frequent battery replacements and secure from interference and malicious attacks. This book lays the foundations of how BANs can be redesigned from a cyber-physical systems perspective (CPS) to overcome these issues. Introducing cutting-edge theoretical and practical techniques and taking into account the unique environment-coupled characteristics of BANs, the book examines how we can re-imagine the design of safe, secure and sustainable BANs. It features real-world case studies, suggestions for further investigation and project ideas, making it invaluable for anyone involved in pervasive and mobile healthcare, telemedicine, medical apps and other cyber-physical systems.
This book provides the reader with the knowledge required in order to understand the chemical, physical, mechanical, and topographical aspects of implant surfaces, as well as their impact on the biological response. Common ways to modify implant surfaces are described, and methods for the evaluation of surface properties are presented in an easy-to-read style. Experimental results that have contributed to surface modifications relevant for commercial available implants are presented, with emphasis on in vivo and clinical studies. While the focus is primarily on surface modifications at the micrometer and nanometer levels, alterations at the millimeter level are also covered, including thread designs and their possible influence on stress distribution. In addition, it is analyzed how surface alterations have changed the clinical long-term results for certain groups of patients.
Learn about the state of the art in building artificial membranes and synthetic biological devices, and in constructing mathematical models for their dynamics at multiple time and spatial scales with this comprehensive book. Drawing on recent advances in bioengineering and biochemistry, it describes how to engineer tethered bilayer lipid membranes, bioelectronic interfaces, high-resolution biosensors, and diagnostic devices for non-invasive cellular measurements and electroporation. Multi-physics models combining atomistic (molecular dynamics and coarse-grained molecular dynamics), mesoscopic (Poisson-Nernst-Planck), and macroscopic (reaction-rate theory) dynamics provide a complete structure-to-function description of these devices. Experiments and dynamic models explain how anti-microbial peptides penetrate membranes, how molecular machine biosensors built out of artificial membranes can detect femtomolar concentrations, and how electroporation can be controlled. Supported by atomistic simulation code online, this is essential reading for researchers, students and professionals in bioengineering, chemical engineering, biophysics, applied mathematics, and electrical engineering.
MATLAB Programming for Biomedical Engineers and Scientists provides an easy-to-learn introduction to the fundamentals of computer programming in MATLAB. This book explains the principles of good programming practice, while demonstrating how to write efficient and robust code that analyzes and visualizes biomedical data. Aimed at the biomedical engineer, biomedical scientist, and medical researcher with little or no computer programming experience, it is an excellent resource for learning the principles and practice of computer programming using MATLAB. This book enables the reader to: Analyze problems and apply structured design methods to produce elegant, efficient and well-structured program designs Implement a structured program design in MATLAB, making good use of incremental development approaches Write code that makes good use of MATLAB programming features, including control structures, functions and advanced data types Write MATLAB code to read in medical data from files and write data to files Write MATLAB code that is efficient and robust to errors in input data Write MATLAB code to analyze and visualize medical data, including imaging data For a firsthand interview with the authors, please visit http://scitechconnect.elsevier.com/matlab-programming-biomedical-engineers-scientists/ To access student materials, please visit https://www.elsevier.com/books-and-journals/book-companion/9780128122037 To register and access instructor materials, please visit http://textbooks.elsevier.com/web/Manuals.aspx?isbn=9780128122037
This step-by-step guide to medical technology innovation, now in full color, has been rewritten to reflect recent trends of industry globalization and value-conscious healthcare. Written by a team of medical, engineering, and business experts, the authors provide a comprehensive resource that leads students, researchers, and entrepreneurs through a proven process for the identification, invention, and implementation of new solutions. Case studies on innovative products from around the world, successes and failures, practical advice, and end-of-chapter 'Getting Started' sections encourage readers to learn from real projects and apply important lessons to their own work. A wealth of additional material supports the book, including a collection of nearly one hundred videos created for the second edition, active links to external websites, supplementary appendices, and timely updates on the companion website at ebiodesign.org. Readers can access this material quickly, easily, and at the most relevant point in the text from within the ebook.
Mathematical modelling of physiological systems promises to advance our understanding of complex biological phenomena and pathophysiology of diseases. In this book, the authors adopt a mathematical approach to characterize and explain the functioning of the gastrointestinal system. Using the mathematical foundations of thin shell theory, the authors patiently and comprehensively guide the reader through the fundamental theoretical concepts, via step-by-step derivations and mathematical exercises, from basic theory to complex physiological models. Applications to nonlinear problems related to the biomechanics of abdominal viscera and the theoretical limitations are discussed. Special attention is given to questions of complex geometry of organs, effects of boundary conditions on pellet propulsion, as well as to clinical conditions, e.g. functional dyspepsia, intestinal dysrhythmias and the effect of drugs to treat motility disorders. With end of chapter problems, this book is ideal for bioengineers and applied mathematicians.
This open access book provides a comprehensive overview of the application of the newest laser and microscope/ophthalmoscope technology in the field of high resolution imaging in microscopy and ophthalmology. Starting by describing High-Resolution 3D Light Microscopy with STED and RESOLFT, the book goes on to cover retinal and anterior segment imaging and image-guided treatment and also discusses the development of adaptive optics in vision science and ophthalmology. Using an interdisciplinary approach, the reader will learn about the latest developments and most up to date technology in the field and how these translate to a medical setting. High Resolution Imaging in Microscopy and Ophthalmology - New Frontiers in Biomedical Optics has been written by leading experts in the field and offers insights on engineering, biology, and medicine, thus being a valuable addition for scientists, engineers, and clinicians with technical and medical interest who would like to understand the equipment, the applications and the medical/biological background. Lastly, this book is dedicated to the memory of Dr. Gerhard Zinser, co-founder of Heidelberg Engineering GmbH, a scientist, a husband, a brother, a colleague, and a friend.
Integer linear programming (ILP) is a versatile modeling and optimization technique that is increasingly used in non-traditional ways in biology, with the potential to transform biological computation. However, few biologists know about it. This how-to and why-do text introduces ILP through the lens of computational and systems biology. It uses in-depth examples from genomics, phylogenetics, RNA, protein folding, network analysis, cancer, ecology, co-evolution, DNA sequencing, sequence analysis, pedigree and sibling inference, haplotyping, and more, to establish the power of ILP. This book aims to teach the logic of modeling and solving problems with ILP, and to teach the practical 'work flow' involved in using ILP in biology. Written for a wide audience, with no biological or computational prerequisites, this book is appropriate for entry-level and advanced courses aimed at biological and computational students, and as a source for specialists. Numerous exercises and accompanying software (in Python and Perl) demonstrate the concepts.
Biosensors are devices that detect the presence of microbials such as bacteria, viruses or a range biomolecules, including proteins, enzymes, DNA and RNA. For example, they are routinely applied for monitoring the glucose concentration in blood, quality analysis of fresh and waste water and for food control. Nanomaterials are ideal candidates for building sensor devces: where in just a few molecules can alter the properties so drastically that these changes may be easily detected by optical, electrical or chemical means. Recent advantages have radically increased the sensitivity of nanomaterial-based biosensors, making it possible to detect one particular molecule against a background of billions of others. Focusing on the materials suitable for biosensor applications, such as nanoparticles, quantum dots, meso- and nanoporous materials and nanotbues, this text enables the reader to prepare the respective nanomaterials for use in actual devices by appropriate functionalization, surface processing or directed self-assembly. The emphasis throughout is on electrochemical, optical and mechancial detection methods, leading to solutions for today's most challenging tasks. The result is a reference for researchers and developers, disseminating first-hand information on which nanomaterial is best suited to a particular application - and why.
Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. Cutting-edge coverage of stem cell biology and applicationsFeaturing contributions from leading global experts, this authoritative volume addresses all major areas of stem cell biology and their potential therapeutic applications. The first part of the book covers embryonic stem cells and contains details on the emerging field of embryonic stem cell-based drug screening platforms. The second part deals with multipotent adult stem cells from different tissue types, and covers unique concepts such as cancer stem cells and tissue engineering-based approaches for designing microenvironments for tissue regeneration. Eighty pages of inserts with 113 color figures are included in this pioneering work. Coverage includes: Zebrafish, medaka, chicken embryonic, and mouse embryonic stem cells Derivation of human embryonic stem cells (hESCs) from blastocysts Treating diabetes with hESCs hESCs as a model system to study human genetics Application of hESCs in drug discovery Adult stem cells for regenerative medicine and cancer therapies Mesenchymal stem cells for neurodegenerative disease therapies Dental pulp, hematopoietic, and spermatogonial stem cells Epigenetic regulators of stem cell pluripotency Cancer stem cells
You may like...
Femtosecond Biophotonics - Core…
Min Gu, Daniel Day, … Hardcover
Artificial Tactile Sensing in Biomedical…
Siamak Najarian, Javad Dargahi, … Hardcover R2,720 Discovery Miles 27 200
Managing Discovery in the Life Sciences…
Philip A. Rea, Mark V. Pauly, … Paperback R688 Discovery Miles 6 880
Handbook of Biomedical Telemetry
Konstantina S. Nikita Hardcover
Biomedical Engineering - Bridging…
W. Mark Saltzman Hardcover R1,240 Discovery Miles 12 400
Computational Approaches in Biomedical…
Ayesha Sohail, ZhiWu Li Hardcover
Biological and Biomedical Coatings…
Sam Zhang Hardcover R5,328 Discovery Miles 53 280
Biological and Biomedical Coatings…
Sam Zhang Hardcover R2,987 Discovery Miles 29 870
Biological and Biomedical Coatings…
Sam Zhang Hardcover R3,720 Discovery Miles 37 200
Fundamentals of Biostatistics
Bernard (Harvard University Rosner Hardcover