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This third volume in the "Progress in Hypertension" series is dedicated to the memory of Professor Kozo Okamoto the creator of spontaneously hypertensive rats (SHR), stroke-prone spontaneously hypertensive rats (SHRSP) and malignant stroke-prone spontaneously hypertensive rats (M-SHRSP). The papers in this volume deal with pathophysiology and pharmacology of SHR. The contributions describe new trends in SHR research from haemodynamic characteristics to immunological views. The emphasis is placed on the development of transgenic rats and the use of tissue culture studies to elaborate SHR characteristics. The possible use of SHRSP as a model of cerebrovascular dementia can also serve as a novel concept to facilitate the study of vascular dementia. The role of excitatory amino SHR are also covered in this book.
Dr Kusumoto s unique new book takes a step-wise, patient-centered approach to guide readers through the thought process required during an electrophysiology study and the development of new findings. * Follows a case based step-wise approach focused on the EP lab that allows readers to follow along with the thought process behind how experienced electrophysiologists first diagnose, then prepare, treat and manage patients with common rhythmic abnormalities, including atrial fibrillation * Written by award-winning Mayo Clinic Physician-educator Dr. Fred Kusumoto * Ideal for fellows, new EPs, nursing and technical staff in the EP lab * Includes clinical questions to help readers test their understanding of the steps and concepts covered in the book and prepare for certification exams
Disease conditions that affect the human heart and the methods used to diagnose and treat them are all covered in one concise volume. * Illustrations include diagrams of the heart, examples of test results, and images of devices used to treat heart disease * A glossary defines medical terms used in the book
This book provides a concise overview over the pathology of retinal angiogenic diseases and explains why anti-angiogenic therapy is effective in so many patients. The reader is guided through the various clinical indications for anti-angiogenic therapy and made aware of its merits as well as current challenges and limitations. It is explained how, since its introduction for the treatment of exudative age-related macular degeneration in 2006, anti-angiogenic therapy has revolutionized the way in which we treat a range of ocular diseases. All of the authors are established experts in their respective fields who share their extensive knowledge and clinical experience with the reader. This book is both a valuable introduction to anti-angiogenic therapy in ophthalmology and a day-to-day companion for all ophthalmologists seeing patients with some of the most prevalent retinal diseases.
The increase of emotional stress has disturbing effects on the neurohumoral regulation of metabolic processes, especially in relation to the cardiovascular system, and increases the changes of organisms developing atherosclerosis. This book studies the effects on the cardiovascular system (in IHD patients) caused by emotions of diverse biological qualities (both positive and negative). At the same time, the relationship between these effects on the functional activity of various hormonal systems and the blood coagulation system are studied in order to determine the mechanisms and development of atherosclerotic processes.
This issue of Interventional Cardiology Clinics will explore Transcatheter mitral valve repair and replacement. Curated by the series Editor-in-Chief, Dr. Matthew J. Price, this issue will cover topics and advances in the field that are relevant for practicing clinicians. This issue is one of four selected each year by Dr. Price. The volume will include articles on: Transcatheter Mitral Valve Direct Annuloplasty With the Millipede Device, Transcatheter Mitral Valve Replacement with Intrepid, Transcatheter Mitral Valve Replacement with Tendyne, Treatment of functional mitral regurgitation with transcatheter edge-to-edge repair, Transcatheter Edge-to-Edge repair for Degenerative Mitral Regurgitation, Predicting Left Ventricular Outflow Tract Obstruction Following Transcatheter Mitral Valve Replacement, Prevention and Treatment of Left Ventricular Outflow Tract Obstruction after Transcatheter Mitral Valve Replacement, and Transatrial implantation of transcatheter heart valve for mitral disease, among others.
Netter's Cardiology, 2nd Edition, by Marschall S. Runge, Cam Patterson, and George Stouffer, uses visually rich Netter artwork to efficiently provide you with a concise overview of cardiovascular anatomy, pathophysiology, diagnosis, and management. In print and online, you'll rapidly access complete introductions to common issues in cardiology, including annotated references of the most important articles, guidelines, and available evidence. Downloadable images and over 20 printable patient handouts facilitate patient education and enhance your personal presentations. Netter - it's how you know. Efficiently review key details of anatomy, pathophysiology, and clinical presentation with detailed, crystal-clear artwork by Frank H. Netter, MD and other illustrators working in the Netter tradition. Apply dependable clinical advice from Marschall S. Runge, MD, PhD, Cam Patterson, MD and George Stouffer, MD and utilize diagnostic and therapeutic algorithms and clinical pathways developed by the many world-renowned chapter contributors. Utilize annotated references to the most important resources and evidence-based studies. Benefit from expanded coverage of cardiovascular imaging including echocardiography, stress testing and nuclear imaging, and CT and MRI. Access the complete searchable contents online, download Netter artwork for your personal use, and print patient education handouts to share the visual didactic power of Netter with your patients. Gain a concise and visual overview of the common conditions in cardiology
Written by world-renowned leaders in the fields of clinical electrophysiology and arrhythmology, the volume has represented since many years a biannual update on the most recent advances in the diagnosis, prognosis and treatment of cardiac arrhythmias. The main chapters deal with atrial fibrillation and other supraventricular tachyarrhythmias, diagnosis and management of ventricular arrhythmias, risk stratification and prevention of sudden death in post-MI patients. The systematic and didactic approach to each topic makes the book a very useful tool for physicians working in the field.
Smoking, diet, stress, coping, and exercise, among other behaviors and psychological states, are now clearly implicated in the development of cardiovascular diseases. Prevention, based largely on altering behaviors that contribute to this chronic disease, is now as important a goal as is treatment of those already afflicted. This volume, based on a recent meeting of the Academy of Behavioral Medicine Research, addresses several important areas of research in the general area of cardiovascular disease. The topics covered reflect on important aspects of this phenomenon, such as the long-term development of coronary artery disease; central nervous system (CNS) regulation of blood pressure, heart rate, and sympathetic tone playing a pivotal role in sympathetic activity and hypertension; learned blood pressure modulation and baroreceptor activation as a means of reducing the aversiveness of stress or noxious stimulation; and the notion that symptoms of heart disease or infarction may occur in the absence of organic heart disease. Having been impressed by the recent advances in the field, the editors of this book capture the wealth of newly acquired knowledge about behavioral factors in cardiovascular disease and how the body's nervous, endocrine, and cardiovascular systems work together.
This new edition is an integral source of information on Atherosclerosis. It covers topics such as newer coronary risk factors, high-density lipoprotein metabolism, lipid-lowering drugs, endothelium and thrombosis in atherogenesis, and contributing risk factors. With over 500 exceptional photographs, diagrams, and charts, each chapter illustrates an important facet of diagnosing and treating this common and often fatal disease.
This book describes the most recent insights into heart failure and the role played by autonomic nervous system pathophysiology in it, discussing the therapeutic implications. While current therapeutic approaches are able to control the effects of excessive adrenergic activation in heart failure syndrome, the underlying abnormalities of adrenergic control remain unaltered and can still cause progression to unmanageable end-stage heart failure. New therapeutic pathways are therefore being explored with a view to developing interventions that can directly modulate adrenergic over-activity and restore a more appropriate balance in neural control of the cardiovascular system. The book opens by examining current heart failure therapies. Advances in our understanding of autonomic regulation/dysregulation in heart failure are then discussed in detail, in the context of the search for more effective therapies. A concluding section addresses the role of autonomic nervous system denervation in heart failure. The authors are top scientists from leading research centers.
This book is a practical guide to the differential diagnosis and treatment of patients presenting in the Emergency Department with syncope or arrhythmias, including bradyarrhythmias, atrial fibrillation, narrow and wide QRS tachycardias. In addition, clear advice is provided on the management of patients with cardiac devices and possible dysfunction, electrical storm, or a requirement for urgent surgery. For each topic, a literature review of epidemiology, physiopathology, differential diagnosis, and treatment is conducted. Furthermore, practical suggestions are offered for short-term management, e.g., regarding the decision on when and where to hospitalize the patient; these proposals do not replace but rather summarize or integrate the current guidelines. The book is designed both for emergency physicians and cardiologists, who will be the first to evaluate and treat patients with arrhythmias or potentially arrhythmic problems in the emergency setting. It will also be a useful textbook for students and residents in Cardiology and Emergency Medicine.
Everything you need to know about a pacemaker or defibrillator Implantable cardiac devices are life-saving tools that have been in use for decades. But when you or a loved one has been advised to get a pacemaker, implantable cardioverter-defibrillator (ICD), or cardiac resynchronization therapy (CRT) device, where do you turn for practical information about what life with your device will be like? The fact is that no single source provides patients and their families with the real-life information they need and want. Until now. Understanding Your Pacemaker or Defibrillator: What Patients and Families Need to Know fills this void with a wealth of useful information for patients who have or require an implantable device. Written from a uniquely comprehensive perspective by three very diverse experts - an experienced cardiologist who has worked with thousands of cardiac device patients and their families, a certified cardiac device specialist who also specializes in patient psychology, and a patient living with an implanted cardiac device - this book explains everything you need to know about living with a pacemaker, ICD, or CRT device including normal and abnormal heart function, misperceptions about implantable devices, what to expect during and after the procedure, follow-up care and possible complications, and practicalities of living with an implanted device. Using accessible, understandable language, Understanding Your Pacemaker or Defibrillator will answer your questions (even the ones you didn't know to ask!), allay your fears, and help you live a long and healthy life with your device.
This book provides comprehensive information on transcatheter aortic valve implantation (TAVI), which was introduced for the treatment of aortic valve disease less than two decades ago. It explains how TAVI has delivered satisfactory results even in high and intermediate risk patients and outlines how it continues to evolve, thus requiring awareness of state of the art approaches to indication, risk stratification, device choice, procedure, and follow-up. In addition, it reports on the complex and multidisciplinary approach needed to maximize the efficacy, safety, and appropriateness of TAVI, providing detailed clinical, interventional and surgical perspectives focusing on the development of this cardiovascular intervention. Starting with the history of TAVI, addressing the interventional anatomy of aortic valve disease, and reporting on the expert authors' day-to-day experiences, this highly informative book offers an essential update for all cardiologists and surgeons interested in transcatheter aortic valve implantation, as well as any clinician, decision-maker and stakeholder involved in patient selection, procedural management, and follow-up.
Now in its second edition, this practical guide offers clear-headed guidance to the successful application of catheter ablation for atrial fibrillation. This book concentrates on clinically-relevant information that providers can put to immediate use caring for patients. * Takes a clear-headed practical approach to ablation of atrial fibrillation long on actionable, clinically-relevant guidance, succinct and to-the-point on the theory behind the procedure * Edited by three leading, internationally-known electrophysiologists with extensive experience in ablation for atrial fibrillation * Written by international team of experts reflecting global best practices from centers with considerable experience in the use of catheter ablation * Format designed to serve the needs of electrophysiologists regardless of experience, electrophysiology fellows, electrophysiology nurses and lab technical staff * Covers hot topics such as new noninvasive imaging techniques, the treatment of challenging left atrial flutters, options for persistent atrial fibrillation and when a redo ablation is needed; and novel application of ablation targeting the autonomic nervous system
This book provides a comprehensive account of the role of echocardiography in patients with mitral valve disease. The normal echocardiographic anatomy of the mitral valve is first presented, and the applications of echocardiography in mitral valve disease are then covered in detail by experts from different subspecialties in cardiology. Topics include etiology, pathophysiology, diagnosis, assessment of severity, and role of echocardiography in percutaneous and surgical techniques. The highly readable text is supported by a wealth of color images obtained with 3D echocardiography, currently the gold standard for the evaluation of mitral valve disease. The interdisciplinary approach used in describing the diagnostic and therapeutic applications will make this book useful for the clinical cardiologist as well as the echocardiographer. It will allow cardiologists to advance their knowledge in the field and will serve as an excellent updating tool for professionals engaged in echocardiography and cardiac diagnostic imaging.
2004 AJN BOOK OF THE YEAR AWARD WINNER! An American Journal of Nursing 2004 Book of the Year! Arrhythmia Recognition: The Art of Interpretation uses hundreds of four-color graphics to communicate the complex topics related to arrhythmia recognition. The text focuses on the pathophysiological mechanisms involved in the formation and maintenance of complex arrhythmias and on their clinical recognition. Each rhythm strip provides a descriptive table outlining the various abnormalities in a logical, easy-to-follow sequence. In addition, there are analytical narratives outlining what providers should consider when approaching the strip. The tables and analytical narratives are intended to formulate functional interpretative skills to consider when approaching a complex arrhythmia in a clinical situation.
For more than 30 years, The Secrets Series has provided students and practitioners in all areas of health care with concise, focused, and engaging resources for quick reference and exam review. Cardiology Secrets, 5th Edition, features the Secrets' popular question-and-answer format that also includes lists, tables, and an easy-to-read style - making reference and review quick, easy, and enjoyable. The Secrets Series format gives you the most return for your time - concise, easy to read, engaging, and highly effective - now with an improved organization that makes information even easier than ever to find. Written by global experts and thought leaders in cardiovascular disease. Top 100 Secrets and Key Points boxes provide a fast overview of the secrets you must know for success in practice. Portable size makes it easy to carry with you for quick reference or review anywhere, anytime. New dedicated sections on peripheral vascular and cerebrovascular disease, venous thromboembolic disease, and specific populations and conditions, plus a dedicated chapter on new direct oral anticoagulant agents. New chapters added on hypercoagulability states, specific valvular lesions, sleep apnea and the heart, heart disease in women, cardio-oncology, cardiac arrest, transcatheter aortic valve replacement (TAVR), carotid artery disease, and hemorrhagic stroke. Several hundred illustrations, figures, and flow diagrams - 100+ are new! Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, Q&As, and references from the book on a variety of devices.
Authored by the same stellar editors and contributors responsible for Kaplan's Cardiac Anesthesia, this title presents today's most essential clinical knowledge in cardiac anesthesia in a practical, user-friendly format. A manageable size and affordable price makes this an ideal purchase for every clinician who would like an economical yet dependable resource in cardiac anesthesia. Trusted authorities deliver the key cardiac anesthesia knowledge you need to know. A concise, user-friendly format and key points boxes in each chapter help you quickly locate crucial information. Annotated references guide you to the most practical additional resources. A portable size and clinical emphasis facilitates and enhances bedside patient care. Designed as a companion to Kaplan's Cardiac Anesthesia. Includes new topics vital to the current practice of cardiac anesthesiologists, such as transesophageal echocardiography; percutaneous valve procedures; new pacemakers and automatic internal defibrillators used for cardiac resynchronization therapy; left ventricular assist devices and extracorporeal membrane oxygenation therapy of heart failure; and patient safety issues. Focuses on today's most current and relevant therapies, including New Cardiac Drugs, and Heart Mate, Heart Ware, and Impella LVADs. Describes care of the cardiac patient in Hybrid Operating Rooms, Catheterization Laboratories, and Electrophysiology Laboratories, as well as the Cardiac Operating Rooms. Perfectly suited for residents, fellows, nurse anesthetists and anesthesiologists in practice.
Prepare yourself for success with this unique cardiology primer which distils the core information you require and presents it in an easily digestible format. * Provides cardiologists with a thorough and up-to-date review of cardiology, from pathophysiology to practical, evidence-based management * Ably synthesizes pathophysiology fundamentals and evidence based approaches to prepare a physician for a subspecialty career in cardiology * Clinical chapters cover coronary artery disease, heart failure, arrhythmias, valvular disorders, pericardial disorders, and peripheral arterial disease * Practical chapters address ECG, coronary angiography, catheterization techniques, ecnocardiography, hemodynamics, and electrophysiological testing * Includes over 650 figures, key notes boxes, references for further study, and coverage of clinical trials * Review questions at the end of each chapter help clarify topics and can be used for Board preparation - over 375 questions in all!
There is no standard textbook at this time on endovascular management of thoracic aortic pathologies. Atlas of Thoracic Aortic Endografting contains clinical case scenarios as well as controversies to highlight the use of this new technology. The various aortic pathologies are discussed, combining etiology, diagnostic tools like intravascular ultrasound (IVUS) and 64 slice CT scans which are all state of the art technologies, endovascular treatment, management of endoleaks, reinterventions combined with techniques of trouble shooting. This book highlights the new changes in the management of thoracic aortic diseases.
Ideal for cardiologists, surgeons, and referring physicians who need a clinical guide to interventional procedures, Textbook of Interventional Cardiology focuses on the latest treatment protocols for managing heart disorders at every level of complexity. In this updated edition, Dr. Topol continues to bring together experts in the field who present the current state of knowledge and clinical practice in interventional cardiology, including cutting-edge theories, trends, and applications of diagnostic and interventional cardiology, as well as peripheral vascular techniques and practices. Offers an in-depth understanding of cardiology, making it well suited for cardiology and interventional cardiology exam preparation. Expert guidance from leading authorities ensures a fresh and balanced perspective on every aspect of interventional cardiology. Presents the most recent genetic information and clinical trials related to interventional cardiology. Highlights the latest treatment advances, procedures, devices, and techniques, including transcatheter aortic valve implantation (TAVI). Brand-new chapters include Radiation Safety, Renal Denervation for Resistant Hypertension, Post PCI Hospitalization, Length of Stay and Discharge Planning, and Interventional Heart Failure. Offers balanced coverage of the entire scope of technologies available, without favoring one particular device over another. Integrates the latest trial data into discussions on clinical practice and recommendations. Multiple images of devices and intra-procedural imaging enhance your visual understanding of the material. Key Points boxes at the beginning of each chapter summarize the most important facts. Features 45 videos easily accessible via Expert Consult. Expert Consult eBook version included with purchase. This enhanced eBook experience offers access to all of the text, figures, videos, and references from the book on a variety of devices.
A comprehensive, accessible summary of the latest research in heart disease risk factors Cardiovascular Disease (CVD) is a major cause of early death and disability across the world. The major markers of risk--including high blood cholesterol, smoking, and obesity--are well known, but studies show that such markers do not account for all cardiovascular risk. Written by a team of renowned experts in the field, this comprehensive and accessible book examines the evidence for emerging and novel risk factors, and their relationship with diet and nutrition. Fully updated throughout, Cardiovascular Disease: Diet, Nutrition and Emerging Risk Factors, 2nd Edition covers everything from the epidemiology of cardiovascular disease, to genetic factors, to inflammation and much more - offering invaluable advice on reducing risk factors and preventing CVD. This new edition: Authoritatively reports on the link between emerging aspects of diet, lifestyle and cardiovascular disease risk Focuses on novel risk factors of CVD, including the human gut microbiome and fetal and childhood origins, and how it can be prevented Features recommendations for interventions and future research Includes references, commonly asked questions that summarise the take-home messages, and an online glossary Cardiovascular Disease: Diet, Nutrition and Emerging Risk Factors, 2nd Edition is an important book for researchers and postgraduate students in nutrition, dietetics, food science, and medicine, as well as for cardiologists and cardiovascular specialists.
This issue of Cardiac Electrophysiology Clinics, guest edited by Mohammad Shenasa and Amin Al-Ahmad, will focus on Advances in Cardiac Mapping and Catheter Ablation. This is part one of a two-part issue and will include articles centered around Basic Concepts in Cardiac Mapping, Novel Mapping & Imaging Systems & Technologies, and Catheter and Energy Sources. Topics include, but are not limited to, Embryology of the Cardiac Conduction System Relevant to Cardiac Arrhythmias; Anatomical Consideration Relevant to Atrial and Ventricular Arrhythmias; Fundamentals of Cardiac Mapping; Novel Cardiac Mapping Systems; Non-invasive Mapping & ECGI in Atrial and Ventricular Arrhythmias; Optical Mapping; Omnipolar Mapping; Cardiac CT, MRI, and Fibrosis Quantification; High resolution mapping in patients with atrial and ventricular arrhythmias; Contact Force and Ablation Index; and New Catheter Balloons Including Radiofrequency.
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