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Neoplastic mimics or "pseudotumors" can simulate neoplasms on all levels of analysis-clinical, radiologic, and pathologic-and thus represent particular diagnostic pitfalls for the pathologist that can ultimately lead to therapeutic misdirection.
Hundreds of color images and analysis of diagnostic mimics guide the pathologist through recognizing and distinguishing the unusual variants, morphologic anomalies, and misleading features that may easily lead to an inaccurate interpretation and missed diagnosis. Since many of the entities described are uncommon, "Neoplastic Mimics in Thoracic and Cardiovascular Pathology" emphasizes imaging and clinical correlations throughout to support the pathologist as consultant to the entire diagnostic and clinical management team. Every pathologist who sees skin cases will find this book an invaluable working tool to ensure accurate diagnosis.
This book provides the pathologist with detailed morphologic descriptions and diagnostic guidance in recognizing these neoplastic mimics as they occur in the skin. In addition, descriptions and diagnostic guidance are provided for the range of skin lesions that may mimic benign masses but are in fact neoplastic. Throughout the book comparisons of neoplastic mimics with true neoplasms are provided, at clinical, gross, and histologic levels. In the presentation of every entity, the points that contribute to differential diagnosis are emphasized.
"Neoplastic Mimics in Dermatopathology" Features: Nearly 500 high-quality images showcase the full range of nonneoplastic and neoplastic mimics in skin Concise, specific text descriptions to make the book easy to use as a visual reference Expert authors guide the reader to recognizing and distinguishing misleading specimens
This book focuses on the coronary bioresorbable scaffold, a new interventional treatment for coronary artery disease, differentiated from a permanent metallic stent. The book provides an overview of the technology including non-clinical studies and clinical evidences in order to help clinicians understand the appropriate application of the technology and the optimal techniques of implantation. It covers the basics of bioresorbable scaffolds; bench test results; preclinical studies; clinical evidences; and tips and tricks of implantation.
This book gives you a new angle on the word `cholesterol'. It explains how the heart functions and what really causes heart disease. You will learn how to treat it, prevent it and, importantly, how to resolve it... naturally. This brilliant book arms professionals and laymen alike with a personal understanding of their health and how cholesterol has been hijacked as the bad guy in the face of massive research to the contrary. Together, Dr Dzugan and Jill. D. Davey offer a definitive guide on how to regain control of our health. It opens up a whole new world of truth and logic that will empower everyone to start taking control of their own health and rethink the current destructive paradigm that often exists on the other side of the waiting room. Despite the abundance of statins on the marketplace, cardiovascular disease is still the number-one killer in the Western world. Find out how restorative medicine can solve the issue of high cholesterol - no statins involved! You will learn the myriad of side effects statin drugs cause and, importantly, why they occur because of these drugs. It presents a reason why doctors should think `ten times' before prescribing these drugs and why patients should think `twenty times' before taking them. This book is a must if cholesterol is of concern to you, a loved one, a friend, or if your physician has recommended statins. Get a second opinion and find out how to resolve high cholesterol naturally with bioidentical hormone restorative therapy and enhance your well-being 360 degrees.
This book covers in detail all aspects of functional mitral and tricuspid regurgitation, from its pathophysiology and natural history, to its assessment, medical and surgical treatment, and long term results. Functional Mitral and Tricuspid Regurgitation encompasses information and knowledge from a diverse background including cardiology, cardiac surgery and basic science. This is necessary for a full understanding of the subject in order to optimally manage patients with this condition.
This book is a detailed practical guide to the use of ventricular assist devices and total artificial hearts to provide mechanical circulatory support (MCS) in patients with end-stage heart failure. It explains why MCS may be indicated, which patients require MCS, when and how to implant ventricular assist devices or a total artificial heart, and how to avoid potential complications of MCS. Management throughout the period of care is described, from preimplantation to follow-up, and both typical and atypical cases are discussed. The text features numerous helpful tips and tricks relating to surgical and nonsurgical management and is supported by a wealth of high-quality illustrations that document the preoperative evaluation and implantation techniques. Heart transplantation remains the gold standard for the treatment of patients suffering from end-stage heart failure, but the shortage of donors has led to an increase in the use of MCS. This book will assist all physicians, and especially cardiologists and anesthesiologists, who are involved in the care of these patients.
This new atlas represents a fresh fresh approach to cardiac anatomy, providing images of unparalleled quality, along with explanatory text, to show in vivo heart anatomy and explain the clinically relevant underlying anatomic concepts. In spite of amazing proliferation of information on the Internet and multiple websites filled with up-to-date information, there is no similarly detailed and systematic compilation of morphological imaging with CT. Organized for both systematic learning and to serve as a quick, yet detailed reference for specific clinical questions, this book is an invaluable resource for medical students and residents, cardiologists, and especially surgeons, interventionalists and electrophysiologists, who depend on ever more detailed imaging support in order to successfully perform increasingly complex coronary and noncoronary structural interventions and other procedures.
There is no accurate record of the number of electrograms recorded annually across the world, but it remains one of the most commonly used non-invasive investigations in the diagnostic armamentarium of the physician, despite or perhaps because of advances made in other techniques. There is evidence to suggest that the numbers of electrograms ordered has risen exponentially in the 1970-1990s and continues to rise today as cardiologists recognize the value of such a direct physiological measure of heart health.
Over the past century, there have been many good publications on the subject of electrocardiology. However, the first edition of this book represented a major contribution to the field. From the outset, the Editors aim was to collate as much as possible of the diverse aspects of the topic into one publication which could become a major reference resource for many years. The field of electrocardiology is not standing still and therefore in the 14 years since this first edition was published, much has occurred and this new edition is extremely timely.
This new edition of this key reference work summarizes the current knowledge of all aspects of theoretical and practical electrocardiology with particular emphasis on the interpretation of the electrocardiogram. The initial volume concentrates on the more theoretical aspects of the topic, as these form the foundations on which further advance is likely to be made. The second and third volumes of the book deal with the more clinical aspects of recording and interpreting the electrocardiogram, with the third volume concentrating on some of the specialized though no less important aspects of electrocardiology and electrocardiography.
Shirt Pocket Companion To The Complete Guide To Ecgs The ECG Criteria Book Provides ECG Criteria For 125 ECG Diagnoses, Including Arrhythmias And Conduction Disturbances; Chamber Enlargement And Hypertrophy; Ischemic Syndromes; Pacemakers; And Drug, Electrolyte And Medical Disorders. Also Includes Sections On Approach To ECG Interpretation, Differential Diagnosis Of ECG Abnormalities, And ACLS Algorithms.
This comprehensive and authoritative text summarizes current evidence and provides experienced perspectives on the etiology, diagnosis, and management of pediatric thrombotic disorders, including arterial ischemic stroke and cerebral sinovenous thrombosis. Authored by leaders in the field, individual chapters are devoted to specific anatomic sites and types of thrombosis. State-of-the-art, pediatric-focused chapters aid in diagnostic evaluation and therapeutic decision making, in settings ranging from the most routine to the most complex and challenging patient scenarios. Topics include: Extremity and Caval Deep Venous Thrombosis; Pulmonary Embolism; Cancer-Associated Thromboembolism; Infection-Associated Thromboembolism; Arterial Ischemic Stroke; Cerebral Sinovenous Thrombosis; Gastrointestinal and Visceral Thrombosis; Developmental Hemostasis; Thrombophilias; Heparin-Induced Thrombocytopenia/Thrombosis Syndrome; Venous Thromboembolism Prevention; Thrombolysis; and Novel Anticoagulants, among others. This text is a 'must-have' for practitioners in pediatric hematology, oncology, hematopoietic stem cell transplantation, neurology, hospital medicine, and intensive care.
Lower Extremity Vascular Disorders (Arterial and Venous) represents a compilation of topics related to lower extremity vascular disorders. It is divided into four sections: (1) Northwestern Vascular Surgery Annual Symposium reflects on its history; (2) Arterial Disease covers exercise therapy for claudication, open and percutaneous common femoral artery interventions for occlusive disease, challenges to and advancements in stent technology, vein harvest and bypass surgery, arterial injuries after knee trauma, and iliac endofibrosis; (3) Venous Disease addresses abdominal and pelvic venous compression syndromes, varicose vein management, acute lower extremity deep venous thrombosis, and approaches to venous ulcers; (4) Wounds consists of one chapter covering advances in wound management. The annual symposium on vascular surgery, sponsored by the Division of Vascular Surgery at the Northwestern University Feinberg School of Medicine, addresses contemporary topics and controversies in vascular and endovascular surgery. Presentations at the symposium cover the full spectrum of vascular surgery, including changes in management of extracranial cerebrovascular disease, new treatment options for lower extremity arterial occlusive disease, hemodialysis access, improvements in techniques for complex venous disease, and developments in aortic stent graft repair in the chest and abdomen. The Modern Trends in Vascular Surgery series is a topical compilation of the standout presentations from the most recent three symposia.
Although it is widely recognized that environmental factors such as smoking, diet, exercise, and socioeconomic status affect the risk of cardiovascular disease, recent work showing the effects of other environmental factors provides a more complete assessment of the situation. This view has emerged from three developments. Firstly, there has been a sudden explosion in the prevalence of diabetes and obesity which indicates a strong environmental component. Secondly, there is an accumulation of evidence suggesting that most cases of these diseases could be prevented by healthy lifestyle choices. Finally, studies have shown that exposure to environmental pollutants has a significant effect on heart disease risk. This book is the first to provide a comprehensive account of the effects of pollutants on heart disease and to integrate this area of research within the overall theme of environmental cardiology. The introductory chapter outlines the effects of different aspects of the environment on heart disease and provides a context for the discussion that follows. Subsequent chapters give an overview of the effects of particulate matter and discuss the epidemiological studies supporting the link. The book then goes on to cover the effects of pollution on different aspects of cardiovascular disease (hypertension, stroke, heart failure, ischemic heart disease and atherogenesis). Because of a close association between diabetes and heart disease, a discussion of the effects of particulate matter on diabetes is also included. Later chapters discuss the effects of individual pollutants such as vehicular emissions, metals and aldehydes. A review on manufactured nanoparticles is incorporated because these particles represent an important new threat to cardiovascular health. The understanding that emerges from this monograph suggests that we must be more alert to the effects of the environment and develop strategies that target, not only the diseased individual, but also the unhealthy, disease-causing environment. It is essential reading for cardiologists, epidemiologists, urban planners and pollution control specialists.
The first book developed specifically for hospitalists managing the growing number of patients with cardiovascular disorders
Cardiovascular disease is a major cause of hospitalization and mortality worldwide, and will account for approximately twenty million deaths in 2015. Due to this growing problem, many patients are being managed by non-cardiovascular physicians in the inpatient setting. As a result, hospitalists and other inpatient physicians without specialized training in cardiology are faced with uncertainty when contemplating the proper management of these patients.
This book focuses on inpatient cardiovascular medicine in a highly algorithmic and evidence-based approach, so that users will be able to care for their hospitalized patients directly, using the best contemporary evidence available. It emphasizes the practical, immediate application of principles and treatment recommendations into everyday clinical inpatient practice, while simplifying the approach to these patients by utilizing visual aids such as carefully designed charts, illustrations, and diagrams.
Inpatient Cardiovascular Medicine features thoughtful, comprehensive coverage by top experts in the field. Topics include: Cardiovascular History and Physical ExaminationIntroduction to ElectrocardiographyNon-invasive Cardiac Imaging Cardiac Stress Testing and the Evaluation of Chest PainPerioperative Cardiac Evaluation Cardiac ResuscitationAcute Coronary Syndromes: Unstable Angina and Non-ST Elevation Myocardial InfarctionAcute ST-Elevation Myocardial InfarctionChronic Coronary Artery DiseasePeripheral Arterial DiseaseThoracic Aortic DiseaseSystolic Heart FailureDiastolic Heart FailureDilated and Restrictive CardiomyopathyHypertrophic CardiomyopathyHeart Transplantation and Left Ventricular Assist DevicesSyncopeApproach to the Patient with a Narrow Complex TachycardiaApproach to the Patient with a Wide Complex TachycardiaAtrial Fibrillation and Atrial FlutterAntiarrhythmic Drug TherapyCardiac Pacemakers and Implantable DefibrillatorsValvular Heart DiseaseInfective EndocarditisPericardial DiseasesPulmonary HypertensionCardiac Tumors
While some research methods or techniques are applicable in several areas of medicine, research in cardiovascular diseases requires knowledge of an increasing array of procedures, techniques and measurements that are highly specialized and unique to this area of investigation. Edited by senior clinical investigators who are recognized leaders in cardiovascular medicine worldwide, this book provides readers with a comprehensive, practical how-to-do-it review of best-practice techniques for cardiovascular research.
Part of the prestigious Novartis Foundation series, this volume uniquely addresses the use of innate immunity to treat or prevent infectious diseases of the lung.
"Innate Immunity to Pulmonary Infection: "Provides a comprehensive overview of pulmonary infectious diseases, including basic pathology, current and potential therapies, and detailed consideration of the innate biological resistance mechanisms in the lungThoroughly examines the major topic of innate immunity in immunology, which is now seen as key to the pathogenesis of and vaccination strategies for infectious diseasesDescribes the genetic and environmental factors which determine the outcome of infection, such as latency of Tuberculosis, blood stream invasion from local infection, and local target tissue damageCovers the roles of cells such as neutrophils, macrophages and dendritic cells and of molecular components such as Toll-like receptorsDiscusses the clinical applications of the new knowledge regarding innate immunity and how this can be used in both treatment and prevention (vaccination) strategiesIncludes contributions from an international and interdisciplinary group of experts
"Innate Immunity to Pulmonary Infection" is an essential resource for researchers in both industry and academia. It is of interest for all those interested in the disciplines of immunology, virology, biology, biotechnology and genetics.
This brief guide to visual diagnosis helps the novice develop --
and the veteran refresh -- crucial skills that can spare the
patient unnecessary testing and bring the physician one step closer
to an accurate diagnosis.
Dr Saksena draws on his years of experience in teaching and
training to show you the physical signs of cardiovascular disease
that can be spotted by visual examination. For each sign, a color
photograph is paired with explanatory text that:
The book provides corroboration of physical signs and other
diagnostic information whenever possible and offers extensive
references for further study.
After an opening chapter on general observations, the author
describes signs that can be found in the face, ear, mouth and nose,
neck, hand, upper extremity, thorax and back, abdomen, and lower
extremity. An appendix covers rarer syndromes associated with
Whether you are just developing your diagnostic skills or want to be better able to identify signs of cardiovascular disease, you can count on this atlas for dependable advice.
Using a practical, case-based format, this superbly illustrated atlas by Dr. Paul Sorajja is a comprehensive collection of more than 130 professional experiences in treating structural heart disease. Organized by pathology, each case presents key clinical points for practitioners at all levels, from beginner to expert. Cases are provided by interventionalists and surgeons with extensive hands-on experience, and edited by experts in the field Includes more than 130 cases covering the full range of structural procedures formitral valve disease, aortic valve disease, prosthetic valve disease, congenital heart disease, hypertrophic cardiomyopathy, and tricuspid disease. Features more than 500 detailed instructional images for quick visual comprehension of essential aspects of each case. Each case includes clinical information, diagnostic images, bulleted learning points, and explanations and rationales for every step of the procedure. Covers catheter-based therapy for structural heart disease - an increasingly important and rapidly growing therapy for valvular heart disease. Provides operator pitfalls and errors to help optimize success with each procedure. Allows practitioners at all levels of experience to explore, gain insight, and learn important keys for success. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
The formation of blood vessels is an essential aspect of embryogenesis in vertebrates. It is a central feature of numerous post-embryonic processes, including tissue and organ growth and regeneration. It is also part of the pathology of tumour formation and certain inflammatory conditions.
In recent years, comprehension of the molecular genetics of blood vessel formation has progressed enormously and studies in vertebrate model systems, especially the mouse and the zebrafish, have identified a common set of molecules and processes that are conserved throughout vertebrate embryogenesis while, in addition, highlighting aspects that may differ between different animal groups.
The discovery in the past decade of the crucial role of new blood vessel formation for the development of cancers has generated great interest in angiogenesis (the formation of new blood vessels from pre-existing ones), with its major implications for potential cancer-control strategies. In addition, there are numerous situations where therapeutic treatments either require or would be assisted by vasculogenesis (the "de novo" formation of blood vessels). In particular, post-stroke therapies could include treatments that stimulate neovascularization of the affected tissues.
The development of such treatments, however, requires thoroughly understanding the developmental properties of endothelial cells and the basic biology of blood vessel formation.
While there are many books on angiogenesis, this unique book focuses on exactly this basic biology and explores blood vessel formation in connection with tissue development in a range of animal models. It includes detailed discussions of relevant cell biology, genetics and embryogenesis of blood vessel formation and presents insights into the cross-talk between developing blood vessels and other tissues.
With contributions from vascular biologists, cell biologists and developmental biologists, a comprehensive and highly interdisciplinary volume is the outcome.
There has been an exponential increase in the amount of information available on the pathophysiology and management of heart diseases. Meanwhile, understanding of the underlying pathology and physiology has deepened and broadened with new methodologies to monitor cardiac structure and function. These developments have led to an overwhelming amount of information available to students, trainees, and physicians. What is in short supply is a comprehensive yet concise and clear description of the important cardiac conditions and disorders, an approach to their management, and an easily consulted and well-indexed summary to be used at the bedside or in the clinic. This book addresses that need.
This book presents a valuable new perspective on Post-Cardiac Arrest Syndrome (PCAS), which was defined as system failure following whole-body ischemia-reperfusion injuries by the 2008 International Liaison Committee on Resuscitation. Recently, improving the survival rate of PCAS has become a major priority all over the world. A Perspective on Post-Cardiac Arrest Syndrome addresses various aspects, including: neurological outcomes in non-convulsive status epilepticus, target temperature management, interventions for PCAS after acute coronary syndrome, the significance of measuring lactate clearance, a specific scoring system in prognostication for PCAS, therapeutic indications for suicide hanging cases. This book will help a broad readership, including emergency physicians, intensivists, cardiologists and neurologists treating PCAS patients, to understand the history, current issues and future challenges in PCAS, presented by respected experts in this field.
Core Topics in Transesophageal Echocardiography is a highly illustrated, full color, comprehensive clinical text reviewing all aspects of TEE. The text has been written particularly for those who are seeking accreditation in TEE. Section 1 includes chapters on first principles including cardiovascular anatomy, safety issues, indications and contraindications for use, US technology and physics and the details of image acquisition and interpretation in a variety of routine pathologies. Section 2 chapters discuss the use of TEE in a variety of more demanding clinical conditions including valve disease, complex ischaemic heart disease, the use of TEE in critical care and emergency settings, new echocardiography technologies, and TEE reporting. An outstanding free companion website (www.cambridge.org/feneck) contains numerous TEE video clips showing both normal and pathological states. Written by leading TEE experts from EACTA and EAE, this is an invaluable practical resource for all clinicians involved in the care of cardiac patients. A companion website of videos, giving a dynamic understanding of moving structures such as the heart, is also available at www.cambridge.org/features/fox/
Demystifies EKG interpretation.Delivering succinct, clear explanations to help students easily grasp key concepts, this book provides a comprehensive, multifaceted approach to EKG interpretation for NP and PA students, as well as practicing clinicians who need a quick refresher. The second edition retains the book's systematic, physiologic approach that trains readers to follow the same steps in evaluating each EKG. It negates the need for rote memorization by facilitating a genuine understanding of EKG interpretation. Using the patient's presenting symptoms as a starting point, abundant clinical scenarios demonstrate real-life applications for interpreting EKG readings. With scores of figures and tables, and more than 160 EKG tracings, this resource delivers exactly everything PAs and NPs need to provide expert, quality care to their patients.New to the Second Edition:15 new EKG tracings in print30 new case studies with accompanying EKG tracings and teaching points, available onlineBasic review of clinical conditions related to common EKG abnormalitiesNew review questions at the end of each chapterMore complex clinical cases to further challenge the student and increase proficiency in EKG interpretationAdditional diagnostic findings in atrial enlargement, bundle branch blocks, and ventricular hypertrophyUpdated chapter contrasting PVCs with PACsKey points at the end of every chapter
Rapid advancements in cardiac electrophysiology require today's health care scientists and practitioners to stay up to date with new information both at the bench and at the bedside. The fully revised 7th Edition of Cardiac Electrophysiology: From Cell to Bedside, by Drs. Douglas Zipes, Jose Jalife, and William Stevenson, provides the comprehensive, multidisciplinary coverage you need, including the underlying basic science and the latest clinical advances in the field. An attractive full-color design features color photos, tables, flow charts, ECGs, and more. All chapters have been significantly revised and updated by global leaders in the field, including 19 new chapters covering both basic and clinical topics. New topics include advances in basic science as well as recent clinical technology, such as leadless pacemakers; catheter ablation as a new class I recommendation for atrial fibrillation after failed medical therapy; current cardiac drugs and techniques; and a new video library covering topics that range from basic mapping (for the researcher) to clinical use (implantations). Each chapter is packed with the latest information necessary for optimal basic research as well as patient care, and additional figures, tables, and videos are readily available online. New editor William G. Stevenson, highly regarded in the EP community, brings a fresh perspective to this award-winning text. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, videos (including video updates), glossary, and references from the book on a variety of devices.
Fetal Echocardiography is a comprehensive, lavishly illustrated guide to fetal heart scanning for anyone involved in obstetric ultrasound. Authored by a leading pediatric cardiologist with over 30 years of experience, it brings together all the information needed by cardiologists, obstetricians, sonographers or maternal-fetal medicine clinicians in order to obtain clear, high-quality echocardiograms and interpret them. Initial chapters provide the basic principles of echocardiography and how to obtain the standard views, giving numerous illustrations of each standard view and the possible deviations from normal. Subsequent chapters present a complete pictorial representation of almost all malformations recognised in fetal life. An overview of the likely outcome of each malformation is given, backed up by personal data involving nearly 4000 abnormal fetal hearts. Additional chapters cover Fetal Arrhythmias and Early Fetal Heart Scanning. Highly illustrated and full of practical guidance, Fetal Echocardiography is an invaluable resource for all practitioners involved in obstetric scanning.
Ace the echocardiography boards with this unique review tool! Questions, Tricks, and Tips for the Echocardiography Boards provides one-of-a-kind assistance directly from those who have recently passed the exam - including hundreds of questions and video clips that mimic what you're likely to encounter. The Second Edition also incorporates valuable feedback from Dr. Sorrell's recent fellows, ensuring complete, up-to-date coverage of the information you need to know to perform at your best on the exam. Features 700+ questions and 350+ video clips with thorough explanations of both correct and incorrect answers, helping you place key concepts in the context of clinical practice. Includes a new chapter on how to accurately maneuver the transducer for particular views and make other adjustments, challenging you to go beyond mere book learning to a more complete understanding of optimal image acquisition. Incorporates questions related to new ASE guidelines, including new Class I and Class III indications. Provides test prep techniques as well as tips to save time, reduce anxiety, and optimize exam performance. Includes a practice exam that allows you to test your mastery of the content. Contains hundreds of images, figures, and tables that address key topics. Enhance Your eBook Reading Experience: Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech.
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