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This book describes the biomedical information of albinism to determine the disability of the genetic disorder in albinism (Chapter 1).
Secondly, it describes the international and regional frameworks of disability (Chapter 2). Thirdly, it analyses the human rights perspective of disability as related to albinism (Chapter 3). Human rights apply to all human beings regardless of disability, and focus will be on the relevant Convention on the Rights of Persons with Disabilities. Fourthly, the book demonstrates the understanding of albinism through beliefs, cultures and superstitions (Chapter 4).
The book suggests a way forward, intending to provide some suggestions and recommendations to improve the life of person with disabilities in general and albinism in particular (Chapter 5).
Finally, the role of non-governmental organisations is analysed - which is to raise awareness, boost the self-esteem of their members, advocate for their needs and possibly lobby for an inclusive society (Chapter 6).
This clinical case book serves as a useful guide for dermatologists, internists, family practitioners, pediatricians, and anyone else charged with the care of infectious diseases of the skin of parasitic, fungal, bacterial, and viral origin. The case-based format distinguishes this work from a reference-style textbook, allowing readers to relate the presented cases to their own practice. Clinical Cases in Infections and Infestations of the Skin provides help and insight for clinicians in managing skin disease, with each chapter serving as a springboard for further pursuit and more extensive training. The reader will find useful information and tools to help patients and will enable readers to add to their current clinical regimens by becoming familiar with healing systems beyond medical dermatology. The book will enable those new to the field to develop a literacy and competence in the management of infectious dermatology. For the more experienced learner, it will assist in finding new ways to sharpen diagnostic and treatment acumens.
This book is a quick reference guide to the new, more personalized approaches to the management of skin disorders that have emerged as a result of progress in our understanding of the genetic background and pathophysiology of skin diseases and the diversity of mechanisms underlying their clinical heterogeneity. A wide range of personalized and targeted therapies are described, including those for different skin cancers, chronic inflammatory skin diseases, and autoimmune diseases. In addition, readers will find that the book documents how research results in personalized medicine can be effectively transferred to dermatological practice and looks forward to future treatments that might be developed on the basis of recent research findings. The authors are all recognized experts in the field, and the text is presented in a reader-friendly format and well illustrated.
A fascinating exploration of the skin in its multifaceted physical, psychological, and social aspects Providing a cover for our delicate and intricate bodies, the skin is our largest and fastest-growing organ. We see it, touch it, and live in it every day. It is a habitat for a mesmerizingly complex world of micro-organisms and physical functions that are vital to our health and our survival. It is also a waste removal plant, a warning system for underlying disease and a dynamic immune barrier to infection. One of the first things people see about us, skin is crucial to our sense of identity, providing us with social significance and psychological meaning. And yet our skin and the fascinating way it functions is largely unknown to us. In prose as lucid as his research underlying it is rigorous, blending in memorable stories from the past and from his own medical experience, Monty Lyman has written a revelatory book exploring our outer surface that will surprise and enlighten in equal measure. Through the lenses of science, sociology, and history--on topics as diverse as the mechanics and magic of touch (how much goes on in the simple act of taking keys out of a pocket and unlocking a door is astounding), the close connection between the skin and the gut, what happens instantly when one gets a paper cut, and how a midnight snack can lead to sunburn--Lyman leads us on a journey across our most underrated and unexplored organ and reveals how our skin is far stranger, more wondrous, and more complex than we have ever imagined.
This guide to dermatological treatments provides concise yet comprehensive, up-to-date overviews of treatment guidelines and pearls for a plethora of skin diseases. It is divided into three main sections that address the many different skin diseases, the drugs available for dermatological treatments, and the various methods applied in dermatology, including fillers, botulinum toxin, lasers, dermoscopy, cryosurgery, and electrosurgery. Each skin disease-focused chapter describes current treatments while also providing a brief synopsis of etiology and clinical presentation. Treatment indications and contraindications, modes of action, and dosages are clearly identified. This third edition of the European Handbook of Dermatological Treatments has been extensively revised to reflect the advances of the past decade, including biologic agents for psoriasis, also used as promising off-label treatments in other skin diseases, targeted agents for malignant melanoma and basal cell carcinoma, and new treatment modalities for rosacea, acne, atopic dermatitis, and urticaria, to name but a few. The successful easy-to-use format is retained in this new edition, which is enriched with clinical photos that will make reading a pleasurable as well as a learning experience.
2017 PROSE Award Winner - Multivolume Reference/Science The world's number 1 dermatology information resource Universally respected, Rook's Textbook of Dermatology is the most comprehensive, definitive and best-illustrated reference work for dermatologists of all levels worldwide and has been at the forefront of international dermatology publishing since first appearing in 1968. The Ninth Edition has been radically re-engineered to match the modern day challenges faced by dermatologists. Once again it has been published as a combined digital and print resource, but with a new online platform enabling easier and faster navigation. A common structure to describe and discuss each disorder has been adopted throughout, whilst maintaining the depth of information for which Rook is renowned. A high priority has been placed on the ease of extracting key information quickly: diagnostic algorithms and management ladders help the reader choose appropriate treatment strategies. More images than ever over 5000 in total aid diagnosis by displaying variations in disease manifestations according to body location, skin type and severity. The section on aesthetic dermatology has been greatly expanded with more coverage of procedures in this rapidly developing field. Rook's Textbook of Dermatology, Ninth Edition provides you with: * The very best content from the number one brand in dermatology an essential consultation tool for all dermatologists * An outstanding combined digital/print resource, exhaustively covering every dermatological disorder * A complete overhaul of its content each disorder now follows a consistent templated approach * A fresh approach to the classification of disorders and organization of chapters, of which there are now 160 instead of 80, all organised into 14 logical sections * A newly designed sophisticated online platform with a fast and powerful digital search functionality search by keyword, disorder or chapter or consult the online image database and get expert clinical advice more quickly than ever * Lavishly illustrated chapters with over 5000 colour images showing variation in disease patterns by body location, skin type and severity * Comprehensive coverage of medical, surgical and aesthetic dermatology, as well as the basic science underpinning the field * An experienced British editorial team working with distinguished international authors and associate editor * Greater emphasis than before on clinical studies/trials, society guidelines and the latest ICD codes * While key references remain in the printed version, thousands more are cited in the book and can be accessed online, where each is hyperlinked to the relevant text Rook s Textbook of Dermatology, Ninth Edition is the complete dermatology reference work. More comprehensive than ever, with more images, more disorders covered and faster, more dynamic and wider digital search functionality. It is an essential resource for the modern day dermatologist, whether experienced or at the beginning of a career in dermatology.
How does our diet affect our skin? What makes the skin age? And why can’t we tickle ourselves?
Providing a cover for our delicate and intricate bodies, the skin is our largest, fastest growing and yet least understood organ. We see it, touch it and live in it every day. It's a habitat for a mesmerizingly complex world of micro-organisms and physical functions that are vital to our health and our survival. It’s also one of the first things people see about us and is crucial to our sense of identity. Our skin plays a central role in our lives. And yet how much do we really know about it?
Through the lenses of science, sociology and history, Dr Monty Lyman leads us on a journey across our most underrated and unexplored organ. Examining our microbiome, our love of tattoos and whether or not beauty products really work, he reveals how the skin is far stranger and more complex than you’ve ever imagined.
This abundantly illustrated guide, based on work at the renowned Rancho Los Amigos National Rehabilitation Center, describes and depicts operative techniques for the treatment of the devastating wounds caused by pressure ulcers. Comprehensive information is provided on the surgical anatomy and the variety of wounds that may be encountered. In addition, interventions in patients with complicated ulcers are discussed. Pressure ulcer is a topic of growing importance in the fields of plastic surgery, surgical education, and physical therapy - and also has important psychosocial, medicolegal, and cost management implications. Readers will find Reconstructive Plastic Surgery of Pressure Ulcer to be an ideal aid to appropriate selection of flap surgery in the individual patient. It will help in the achievement of satisfactory outcomes and will especially assist surgeons who lack the requisite specialized training and experience.
This book is a compendium of tips on many different aspects of patch testing based on the recommendations of the International Contact Dermatitis Research Group (ICDRG), which is the reference group for all dermato-allergologists. It is intended to complement the book Patch Testing and Prick Testing: A Practical Guide by J.- M. Lachapelle and H. Maibach, which is an official publication of the ICDRG now in its third edition. Among the wide variety of topics covered are pitfalls, legal aspects, patch testing with ultrasonic bath extracts, the role of patch testing in occupational contact dermatitis and atopic dermatitis, semi-open tests, the implications of a negative test, patch testing validity, selection of extra allergens and patch testing in the tropics. Many illustrations are included and all information is completely up- to-date. This book will be of value to all practicing dermatologists.
Mosaicism is a powerful biologic concept, originally developed from the study of plants and animals, and is the necessary basis for the explanation of numerous human skin disorders. This lavishly illustrated book presents, for the first time, a comprehensive overview of the strikingly manifold patterns and peculiarities of mosaic skin disorders. It is structured in a straightforward, reader-friendly way that will help the dermatologist to understand the underlying molecular mechanisms of skin disorders in order to further improve the treatment outcome. The first two parts of the book are devoted to the mechanisms and patterns of cutaneous mosaicism, with explanation of genomic and epigenetic mosaicism and description of the six archetypal patterns, including the lines of Blaschko, as well as less well defined or as yet unclassifiable patterns. In the third part, the various mosaic skin disorders are examined in depth, including nevi, allelic and non-allelic didymosis, other binary genodermatoses, mosaic manifestations of autosomal dominant skin disorders, and nevoid skin disorders. The book concludes with a note on neoplastic skin lesions, examining models of tumorigenesis.
This atlas, containing more than 300 color photos, focuses on those dermatologic conditions that are most common in ethnic skin or skin of color. It includes succinct explanations of each disease process, describes clinical findings and presents key information on diagnosis and treatment. Individual chapters are devoted to pigmentary disorders, follicular disorders, hair and scalp disorders, eczemas, papulosquamous disorders, granulomatous disorders, connective tissue diseases, infectious diseases, scarring disorders, cutaneous neoplasms, photodermatoses and drug eruptions. The fact that this atlas covers skin disorders that affect patients of all ethnic backgrounds ensures that it will be of worldwide relevance. It will serve as a valuable reference for dermatologists and a range of other health care providers.
Dermatopathology is a specialized branch of pathology in which there has been great progress as new techniques have become available to evaluate the pathology of the skin. Many of the advances in our knowledge and understanding of the skin and the diseases that affect it have been made by people with experience of both diagnostic pathology and clinical dermatology. With significant numbers of large textbooks available, there is a need to provide practical clinical information and concise criteria for pathologic diagnosis for pathologists and dermatologists looking for up-to-date diagnostic and management options.
This book is designed to meet the need for a concise, easy-to-read text on how to approach and manage patients with nail diseases. The book opens with a description of nail anatomy and physiology, followed by a review of nail symptoms, divided according to the part of the nail apparatus involved. Non-invasive and invasive tools for the diagnosis of nail disorders are then described and insights provided into their appropriate use. Subsequent chapters review the various nail diseases, covering inflammatory, infective, environmentally and auto- induced, drug-induced and neoplastic conditions as well as disorders due to systemic diseases. An additional chapter addresses nail conditions commonly seen in toenails. Informative high-quality illustrations are included for each disorder and boxes helpfully summarize the most important features, clues to diagnosis, necessary examinations, and treatments. Nail Disorders: A Practical Guide to Diagnosis and Management will be an invaluable, ready source of information for students in dermatology, clinical practitioners and podiatrists.
This unique book, written by acknowledged experts, provides a comprehensive review of the wide spectrum of skin diseases that may affect the head and neck region and central nervous system. The clearly written, informative text is accompanied by abundant examples of radiological imaging and corresponding vivid clinical photographs. Coverage includes congenital skin lesions, neurocutaneous syndromes, benign and malignant skin tumors, vascular malformations and lesions, trauma, infectious and inflammatory processes, and post-treatment appearances. The book will be an invaluable clinical resource for both neuroradiologists and dermatologists. Patients with skin diseases often undergo neuroradiological imaging, and it is therefore important for neuroradiologists to be familiar with the various types of dermatological conditions and their imaging appearances.
This well-illustrated guide provides concise descriptions of the most frequently encountered cosmetic skin conditions and essential information on commonly employed treatment procedures. The book opens with a description of skin evaluation systems and then documents etiology, pathogenesis, diagnosis, and treatment for various conditions, including cellulite, acne, hirsutism, and striae distensae. The second part of the book provides step-by-step guidelines on a range of cosmetic procedures, such as botulinum toxin injection, cryosurgery, electrosurgery, and injection lipolysis. The advice provided will be invaluable for all physicians who intend to incorporate these procedures into their practices. The book will also be of interest to established specialists in cosmetic dermatology wishing to update their knowledge and to all general dermatologists and plastic surgeons required to answer the numerous questions posed by patients seeking to maintain or improve the quality of their skin. "
This book is unique in focusing expressly on regenerative medicine in the aesthetic field. With the aid of more than 400 color pictures, it provides step-by-step descriptions of procedures that can be performed easily in the private practice. The number of people pursuing anti-aging and cosmetic procedures in order to achieve a youthful, healthy, or simply improved aspect is continually increasing. At the same time the available techniques and materials have undergone rapid innovation in terms of both safety and quality. The practitioner no longer looks just at the correction or camouflage of an unwanted feature but rather also aims to address the aging process itself. Regenerative medicine appears to provide a unique and unlimited opportunity in this context. Autologous fat grafting, adipose-derived stem cells, and autologous platelet-rich plasma represent just some of the attractive options that can be used for volume restoration and facial rejuvenation.
This truly comprehensive reference, in a mini-series format with five volumes, offers a detailed description of both well-known and recently introduced methods for percutaneous penetration enhancement. The first three volumes are devoted to the broad range of chemical methods used to enhance the skin delivery of drugs, including the vast variety of chemical penetration enhancers, drug and vehicle manipulation strategies, nanocarriers, and many others. The fourth volume discusses the diverse physical methods used in penetration enhancement, such as sonophoresis, iontophoresis, electroporation, microporation, laser ablation, and microneedles. Determination of drug penetration is covered in the final volume, with a focus especially on mathematics in skin permeation and modern analytical techniques adapted to assess and measure penetration. This edition of Percutaneous Penetration Enhancers will be an invaluable resource for researchers, pharmaceutical scientists, practitioners, and also students.
The "Abtropfung" theory that nevi develop through the migration of nevus cells from the epidermis to the dermis prevailed for almost a century until the "Hochsteigerung" theory postulated the reverse pattern of migration. Most recently, however, new insights gained from epidemiology, cross-sectional and longitudinal studies of nevi, dermoscopy and confocal microscopy, and cellular and molecular studies have brought into question both of these theories. This book provides a comprehensive guide to current knowledge about nevogenesis by presenting these latest advances and in addition discusses issues yet to be resolved. It will assist practicing physicians in effectively managing patients with a variety of nevi and will also be of great value to researchers in the field. Importantly, since nevi are associated with an increased risk of melanoma, understanding nevogenesis may help to unravel some of the mysteries of melanomagenesis.
An era of global population aging is upon us. By 2030, one in eight people will be over age 65. Since women generally live longer than men, the health and welfare of postmenopausal women will become a significant public health concern. This book offers a comprehensive review of the life changes associated with menopause, both at the dermatological and physiological level (e.g., hormonal, immunological) and at the subcellular level. It critically examines the dermatological, biological, and clinical challenges to postmenopausal health and well-being and the current and emerging therapeutic interventions. The authors advocate a holistic approach, emphasizing the need to view the menopause as a life transition with various facets rather than as a series of distinct medical conditions to be managed. Our goal is to offer a comprehensive resource to the researchers, clinicians, physicians, and helping professions whose mission is to promote the health and well-being of women around the world.
As the number of surviving immune suppressed patients continues to rise, skin manifestations of patients have become increasingly important. AIDS patients, and renal, heart, liver, bone marrow, and lung transplant patients are now living longer and immunosuppressive drugs are being used more frequently. Diabetes is rising in the US and around the world, offering its own unique brand of immune suppressed skin diseases. The skin may be the earliest sign of these conditions and be the organ showing the most profound, earliest, and treatment limiting side effects. Skin Diseases in the Immunocompromised is the most comprehensive book on the topic available. It elucidates the signs of immune suppressed skin diseases to afford early diagnosis and management of this ever-increasing diverse group of illnesses. Organized for easy access, this book will be an essential resource for residents and fellows in dermatology and infectious diseases medical professionals.
Children are no less spared from severe skin diseases. This textbook is designed as a practical clinical reference that will guide practitioners in treating difficult dermatoses in children in whom topical therapy has been unsuccessful. Individual sections are devoted to inflammatory diseases, immune-mediated/autoimmune diseases, tumors and proliferative disorders, and genodermatoses. Each chapter addresses which patients represent suitable candidates for systemic or other non-topical therapy and considerations and caveats in the use of such approaches. Potential treatments are then appraised from a current evidence-based perspective, with provision of detailed but relevant information and reference tables that summarize recommendations in use and monitoring. Future directions in management are also presented.
This book is a cutting-edge resource that provides clinicians with the up-to-date practical knowledge required in order to manage SCC patients optimally. It summarizes newly available information relating to the definition of high-risk SCC, its pathophysiologic underpinnings, and its management. New prognostic information and staging systems are summarized that enable high-risk tumors to be defined more precisely than ever before. Many helpful tips are provided on the practical management of challenging cases, including multiple tumors/field cancerization, high-risk tumors, nodal metastases, and unresectable disease. The authors are all acknowledged experts in the emerging field of high-risk and advanced SCC.
The interpretation of melanocytic tumors represents probably the most difficult task in the field of dermatopathology. The second edition of this text and atlas depicts a broad range of the most important and most challenging melanocytic lesions. Each individual case is illustrated with at least three high-quality color photographs and is commented on at length, highlighting the diagnostic clues. The goal of the authors is to assist the ordinary pathologist in making a precise workable diagnosis in their daily practice. They achieve this by providing simple criteria that will serve as a sound basis for an unequivocal diagnosis of either a benign or a malignant melanocytic neoplasm. The reader will find Histological Diagnosis of Nevi and Melanoma to be an invaluable guide to correct diagnosis even in difficult or rare cases.
This monograph provides specialists and primary care physicians who are interested in hair with the practical know-how needed to achieve successful management of male alopecia. Guidance is first provided on the examination of hair loss in men, covering such aspects as clinical examination, the role of trichoscopy and the trichogram, laboratory work-up, and scalp biopsy. Diagnosis and treatment are then described in depth for a diverse range of conditions involving alopecia. Expert opinion is combined with the results of evidence-based medicine to provide the best current advice, highlighting the synergistic action of combination regimens and adjuvant treatments and explaining the concept of multitargeted treatment. All aspects of follow-up are covered, including compliance issues and expectation management. The role of hair care and cosmetics is also considered, with identification of potential adverse effects as well as benefits.
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