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Turn your microbiology laboratory course into an exciting gateway into the world of microorganisms. With nothing more than microscopes, Petri dishes, media, and a handful of reagents, undergraduates will learn to isolate, grow, and identify a wide range of pathogenic microbes. While becoming proficient at the fundamental skills of the microbiology laboratory-how to streak plates, use a microscope, perform a Gram stain, and prepare serial dilutions and spread plates-Challenges of the Unseen World: A Laboratory Course in Microbiology enables students to solve six challenges that professional microbiologists might encounter in their work. Richard Meyer and Stacie Brown have written a manual that emphasizes discovery and scientific reasoning and meets the ASM microbiology education curriculum guidelines. Students learn essential classic laboratory methods and important molecular techniques as they attempt to investigate real-world medical and epidemiological problems. This approach enhances retention by providing context and shows students how professional microbiologists think and work.
Introduces readers to the state of the art of omics platforms and all aspects of omics approaches for clinical applications This book presents different high throughput omics platforms used to analyze tissue, plasma, and urine. The reader is introduced to state of the art analytical approaches (sample preparation and instrumentation) related to proteomics, peptidomics, transcriptomics, and metabolomics. In addition, the book highlights innovative approaches using bioinformatics, urine miRNAs, and MALDI tissue imaging in the context of clinical applications. Particular emphasis is put on integration of data generated from these different platforms in order to uncover the molecular landscape of diseases. The relevance of each approach to the clinical setting is explained and future applications for patient monitoring or treatment are discussed. Integration of omics Approaches and Systems Biology for Clinical Applications presents an overview of state of the art omics techniques. These methods are employed in order to obtain the comprehensive molecular profile of biological specimens. In addition, computational tools are used for organizing and integrating these multi-source data towards developing molecular models that reflect the pathophysiology of diseases. Investigation of chronic kidney disease (CKD) and bladder cancer are used as test cases. These represent multi-factorial, highly heterogeneous diseases, and are among the most significant health issues in developed countries with a rapidly aging population. The book presents novel insights on CKD and bladder cancer obtained by omics data integration as an example of the application of systems biology in the clinical setting. Describes a range of state of the art omics analytical platforms Covers all aspects of the systems biology approach--from sample preparation to data integration and bioinformatics analysis Contains specific examples of omics methods applied in the investigation of human diseases (Chronic Kidney Disease, Bladder Cancer) Integration of omics Approaches and Systems Biology for Clinical Applications will appeal to a wide spectrum of scientists including biologists, biotechnologists, biochemists, biophysicists, and bioinformaticians working on the different molecular platforms. It is also an excellent text for students interested in these fields.
This book offers a comprehensive overview of research at interface between History, Philosophy and Sociology of Science (HPSS) and Science Teaching in Ibero-America. It contributes to research on contextualization of science for students, teachers and researchers, and explains how to use different episodes of history of science or different themes of philosophy of science in regular science classes through diverse pedagogical approaches. The chapters in this book discuss a wide range of topics under different methodological, epistemological and didactic approaches, reflecting the richness of research developed in Spanish and Portuguese speaking countries, Latin America, Spain and Portugal. The book contains chapters about historical events, topics of philosophy and sociology of science, nature of science, applications of HPSS in the classroom, instructional materials for students and teacher training courses and curriculum.
A Monograph on the Genus Heuchera was first published in 1936. Minnesota Archive Editions uses digital technology to make long-unavailable books once again accessible, and are published unaltered from the original University of Minnesota Press editions.Volume II in the Minnesota Studies in Plant Science seriesThis taxonomic review discusses a number of topics related to the genus heuchera, including: its taxonomic and geographic position; its generic unity; its hybritidy; and its synoptical treatment. The study also offers a detailed description of the genus with an evaluation of various taxonomic characters.
An elegant, witty, and engaging exploration of the riddle of time, which examines the consequences of Einstein's theory of relativity and offers startling suggestions about what recent research may reveal.
The eternal questions of science and religion were profoundly recast by Einstein's theory of relativity and its implications that time can be warped by motion and gravitation, and that it cannot be meaningfully divided into past, present, and future.
In About Time, Paul Davies discusses the big bang theory, chaos theory, and the recent discovery that the universe appears to be younger than some of the objects in it, concluding that Einstein's theory provides only an incomplete understanding of the nature of time. Davies explores unanswered questions such as:
* Does the universe have a beginning and an end?
About Time weaves physics and metaphysics in a provocative contemplation of time and the universe.
The Physico-Chemical Properties of Plant Saps in Relation to Phytogeography was first published in 1934. Minnesota Archive Editions uses digital technology to make long-unavailable books once again accessible, and are published unaltered from the original University of Minnesota Press editions.This book includes data on native vegitation gathered by the noted botanist J. Arthur Harris in the eastern and western United States, the Hawaiian islands, and Jamaica over a period of 18 years. Included more than 12,000 series of determinations of freezing-point depression, specific electrical conductivity, chloride and sulphate content in grams per liter of sap, and occasional determinations of hydrogen ion concentration. A separate index to the data is included for use by those wishing to make ecological studies of plants in particular communities.
Classic text leads from elementary calculus into more theoretic problems. Precise approach with definitions, theorems, proofs, examples and exercises. Topics include partial differentiation, vectors, differential geometry, Stieltjes integral, infinite series, gamma function, Fourier series, Laplace transform, much more. Numerous graded exercises with selected answers. 1961 edition.
Creating a Classroom Community of Young Scientists helps teachers - both pre-service and in-service - to develop exciting science programs in their classrooms. This book provides the groundwork for designing and implementing a science program that takes into account the latest research in teaching and learning. It provides an approach that will capture children's imaginations, stimulate their curiosity and create a strong foundation for their continued interest in, and appreciation of, science and the world in which they live. The book is designed to be user-friendly, and offers an approach to teaching science that is exciting for teachers as well.
This thoroughly revised, second edition focuses on making inquiry more explicit both in terms of the process of inquiry and teaching in ways that capitalize on children's curiosity and questions. New material has also been added on U.S. and Canadian science standards, as well as professional standards for teachers.
Though most historians remember her as the mistress of Voltaire, Emilie Du Chatelet (1706-49) was an accomplished writer in her own right, who published multiple editions of her scientific writings during her lifetime, as well as a translation of Newton's "Principia Mathematica" that is still the standard edition of that work in French. Had she been a man, her reputation as a member of the eighteenth-century French intellectual elite would have been assured.
In the 1970s, feminist historians of science began the slow work of recovering Du Chatelet's writings and her contributions to history and philosophy. For this edition, Judith P. Zinsser has selected key sections from Du Chatelet's published and unpublished works, as well as related correspondence, part of her little-known critique of the Old and New Testaments, and a treatise on happiness that is a refreshingly uncensored piece of autobiography--making all of them available for the first time in English. The resulting volume will recover Chatelet's place in the pantheon of French letters and culture.
For less than $3.00! Build without tools! Sound incredible? Now you can silence any weapon, using items found in any neighborhood supermarket. This detailed manual includes over 65 close-up photographs and drawings to help anyone build disposable silencers that are just as effective as professional models, but can be easily constructed in seconds, without the use of tools, using only inexpensive, readily available items. Items such as: soft drink bottles, window screen, pop bottle caps, PVC pipe, and many more! You wont be able to find this information anywhere else, so order today!
What useful changes has feminism brought to science? Feminists have enjoyed success in their efforts to open many fields to women as participants. But the effects of feminism have not been restricted to altering employment and professional opportunities for women. The essays in this volume explore how feminist theory has had a direct impact on research in the biological and social sciences, in medicine, and in technology, often providing the impetus for fundamentally changing the theoretical underpinnings and practices of such research. In archaeology, evidence of women's hunting activities suggested by spears found in women's graves is no longer dismissed; computer scientists have used feminist epistemologies for rethinking the human-interface problems of our growing reliance on computers. Attention to women's movements often tends to reinforce a presumption that feminism changes institutions through critique-from-without. This volume reveals the potent but not always visible transformations feminism has brought to science, technology, and medicine from within. Contributors: Ruth Schwartz Cowan Linda Marie Fedigan Scott Gilbert Evelynn M. Hammonds Evelyn Fox Keller Pamela E. Mack Michael S. Mahoney Emily Martin Ruth Oldenziel Nelly Oudshoorn Carroll Pursell Karen Rader Alison Wylie
In 2014, California suffered the largest and deadliest outbreak of pertussis, also known as whooping cough," in more than fifty years. This tragedy was avoidable. An effective vaccine has been available since the 1940s. In recent years other diseases, like measles and mumps, have also made a comeback. The reason for these epidemics can be traced to a group whose vocal proponents insist, despite evidence to the contrary, that vaccines are poison. As a consequence, parents and caretakers are rejecting vaccines for themselves and their families.In Deadly Choices , infectious-disease expert Paul Offit takes a look behind the curtain of the anti-vaccine movement. What he finds is a reminder of the power of scientific knowledge, and the harm we risk if we ignore it.
At the turn of the 21st century, the most valuable commodity in society is knowledge--particularly new knowledge that may give a culture, company, or laboratory an adaptive advantage. Knowledge about the cognitive processes that lead to discovery and invention can enhance the probability of making valuable new discoveries and inventions. Such knowledge needs to be made widely available to ensure that no particular interest group "corners the market" on techno-scientific creativity. Knowledge can also facilitate the development of business strategies and social policies based on a genuine understanding of the creative process. Furthermore, through an understanding of principles underlying the cognitive processes related to discovery, educators can utilize these principles to teach students effective problem-solving strategies as part of their education as future scientists. This book takes the reader out onto the cutting edge of research in scientific and technological thinking. The editors advocate a multiple-method approach; chapters include detailed case studies of contemporary and historical practices, experiments, computational simulations, and innovative theoretical analyses. The editors attempt a provocative synthesis of this work at the end. In order to achieve true scientific and technological progress, an understanding of the process by which species are transforming the world is needed. This book makes an important step in that direction by leading to breakthroughs in the understanding of discovery and invention.
Rarely has a scholar attained such popular acclaim merely by doing what he does best and enjoys most. But such is Stephen Jay Gould's command of paleontology and evolutionary theory, and his gift for brilliant explication, that he has brought dust and dead bones to life, and developed an immense following for the seeming arcana of this field. In Time's Arrow, Time's Cycle his subject is nothing less than geology's signal contribution to human thought-the discovery of "deep time," the vastness of earth's history, a history so ancient that we can comprehend it only as metaphor. He follows a single thread through three documents that mark the transition in our thinking from thousands to billions of years: Thomas Burnet's four-volume Sacred Theory of the Earth (1680-1690), James Hutton's Theory of the Earth (1795), and Charles Lyell's three-volume Principles of Geology (1830-1833). Gould's major theme is the role of metaphor in the formulation and testing of scientific theories-in this case the insight provided by the oldest traditional dichotomy of Judeo-Christian thought: the directionality of time's arrow or the immanence of time's cycle. Gould follows these metaphors through these three great documents and shows how their influence, more than the empirical observation of rocks in the field, provoked the supposed discovery of deep time by Hutton and Lyell. Gould breaks through the traditional "cardboard" history of geological textbooks (the progressive march to truth inspired by more and better observations) by showing that Burnet, the villain of conventional accounts, was a rationalist (not a theologically driven miracle-monger) whose rich reconstruction of earth history emphasized the need for both time's arrow (narrative history) and time's cycle (immanent laws), while Hutton and Lyell, our traditional heroes, denied the richness of history by their exclusive focus upon time's arrow.
Tools to make hard problems easier to solve. In this book, Sanjoy Mahajan shows us that the way to master complexity is through insight rather than precision. Precision can overwhelm us with information, whereas insight connects seemingly disparate pieces of information into a simple picture. Unlike computers, humans depend on insight. Based on the author's fifteen years of teaching at MIT, Cambridge University, and Olin College, The Art of Insight in Science and Engineering shows us how to build insight and find understanding, giving readers tools to help them solve any problem in science and engineering. To master complexity, we can organize it or discard it. The Art of Insight in Science and Engineering first teaches the tools for organizing complexity, then distinguishes the two paths for discarding complexity: with and without loss of information. Questions and problems throughout the text help readers master and apply these groups of tools. Armed with this three-part toolchest, and without complicated mathematics, readers can estimate the flight range of birds and planes and the strength of chemical bonds, understand the physics of pianos and xylophones, and explain why skies are blue and sunsets are red. The Art of Insight in Science and Engineering will appear in print and online under a Creative Commons Noncommercial Share Alike license.
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