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Since the first edition of HIV and AIDS Education, Care and Counselling was published almost 20 years ago, it has become the standard handbook in Africa for thousands of HIV and AIDS practitioners. However, ongoing HIV and AIDS research requires regular revisions to the handbook for it to remain current with developments in prevention and treatment. Consequently, this new edition has been updated with input from two new specialist co-authors. This has strengthened the multicultural and multidisciplinary approach of this edition to Africa's unique challenges. Key features: A new design that improves readability and accessibility; In situ definitions and explanations of key terms and concepts; An updated glossary of important HIV and AIDS terminology; and Terminology, Frequently Asked Questions and Enrichment boxes that provide insight into specific aspects of HIV and AIDS prevention and treatment. Key updates: This edition includes a wealth of new information for healthcare practitioners on nursing care principles covering co-infections and complications of HIV infection and ART; infection control; and management of TB, drug-resistant TB, STIs and comorbidities. Specifically, the sixth edition includes: The latest ARV protocols in South Africa; The WHO's best practice suggestions; ART treatment as prevention; HIV, TB and STI prevention and management for schoolchildren, aligned with the Department of Basic Education's Life Skills and Life Orientation criteria; Development of children and adolescents from traditional, communal or collectivistic backgrounds; and The Dual Process Model (DPM), focusing on the latest research in bereavement counselling.
This clinical case book serves as a useful guide for dermatologists, internists, family practitioners, pediatricians, and anyone else charged with the care of infectious diseases of the skin of parasitic, fungal, bacterial, and viral origin. The case-based format distinguishes this work from a reference-style textbook, allowing readers to relate the presented cases to their own practice. Clinical Cases in Infections and Infestations of the Skin provides help and insight for clinicians in managing skin disease, with each chapter serving as a springboard for further pursuit and more extensive training. The reader will find useful information and tools to help patients and will enable readers to add to their current clinical regimens by becoming familiar with healing systems beyond medical dermatology. The book will enable those new to the field to develop a literacy and competence in the management of infectious dermatology. For the more experienced learner, it will assist in finding new ways to sharpen diagnostic and treatment acumens.
Diagnosis and management of infectious disease are among the most common and challenging aspects of emergency practice. Ranging from surgical treatment of a minor skin abscess to recognition of a rare tropical disease in a returning traveler to rapid resuscitation of a patient in septic shock, these problems will be familiar to every practicing acute care provider. Written by both infectious disease experts and practicing emergency physicians, this book is designed specifically for the acute care provider. It covers the most important pathogens and the most common clinical syndromes, organized by system and by special patient populations. The book features a comprehensive narrative, as well as high-yield tables covering key points on diagnosis and treatment. High quality color photographs assist with visual diagnosis. This book provides an invaluable resource for every practicing clinician who confronts the spectrum of infectious disease in the acute care setting.
Infection prevention and control play a significant part in containing the spread of disease. Increased resistance to antimicrobials and the rapid spread of communicable diseases such as tuberculosis, swine flu, SARS and avian flu has highlighted the need for good IPC measures in both the healthcare setting and at home.
Understanding Infection Prevention & Control is a comprehensive compendium of IPC processes that can be applied to all countries. The text embraces the recent developments and recommendations in IPC from international authorities, such as the World Health Organization.
It is an ideal study and teaching tool and will serve as a reference book for healthcare systems planners who wish to understand IPC and strengthen systems.
This well-structured and lavishly illustrated book is a comprehensive reference on intraocular inflammation that encompasses all anatomic forms, settings and etiologies. Individual sections are devoted to uveitis associated with systemic disorders, uveitis syndromes restricted to the eye, bacterial uveitis, viral uveitis, fungal uveitis, parasitic uveitis, uveitis caused by other microbes, traumatic uveitis, and masquerade syndromes. Chapters on the different forms of uveitis are in a homogeneous reader-friendly format, with identification of core messages, explanation of etiology and pathogenesis, up-to-date information on diagnostics and differential diagnosis and guidance on the most appropriate forms of treatment and prognosis. Helpful flow charts are included to assist in identification of potential underlying disorders and the reader will also have online access to one hundred informative case reports demonstrating the different courses of intraocular inflammation. The authors are world experts keen to share their vast experience with the reader. Intraocular Inflammation will be a valuable resource for all physicians who deal with patients with inflammatory eye disease.
This book provides an introduction to the computational and complex systems modeling of the global spreading of infectious diseases. The latest developments in the area of contagion processes modeling are discussed, and readers are exposed to real world examples of data-model integration impacting the decision-making process. Recent advances in computational science and the increasing availability of real-world data are making it possible to develop realistic scenarios and real-time forecasts of the global spreading of emerging health threats. The first part of the book guides the reader through sophisticated complex systems modeling techniques with a non-technical and visual approach, explaining and illustrating the construction of the modern framework used to project the spread of pandemics and epidemics. Models can be used to transform data to knowledge that is intuitively communicated by powerful infographics and for this reason, the second part of the book focuses on a set of charts that illustrate possible scenarios of future pandemics. The visual atlas contained allows the reader to identify commonalities and patterns in emerging health threats, as well as explore the wide range of models and data that can be used by policy makers to anticipate trends, evaluate risks and eventually manage future events. Charting the Next Pandemic puts the reader in the position to explore different pandemic scenarios and to understand the potential impact of available containment and prevention strategies. This book emphasizes the importance of a global perspective in the assessment of emerging health threats and captures the possible evolution of the next pandemic, while at the same time providing the intelligence needed to fight it. The text will appeal to a wide range of audiences with diverse technical backgrounds.
After thirty five years, Mandell, Douglas, and Bennett s Principles and Practice of Infectious Diseases, 8th Edition is still the reference of choice for comprehensive, global guidance on diagnosing and treating the most challenging infectious diseases. Drs. John E. Bennett and Raphael Dolin along with new editorial team member Dr. Martin Blaser have meticulously updated this latest edition to save you time and to ensure you have the latest clinical and scientific knowledge at your fingertips. With new chapters, expanded and updated coverage, increased worldwide perspectives, and many new contributors, Mandell, Douglas, and Bennett s Principles and Practice of Infectious Diseases, 8th Edition helps you identify and treat whatever infectious disease you see. "I highly recommend Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases, together with the included ExpertConsult, the on-line version of the book that is a searchable source and is available to a variety of platforms. It is updated twice each year and is an excellent solution for health-care professionals to keep informed of the latest knowledge" Reviewed by Graefes Arch Clin Exp Ophthalmol, March 2015 "..what an in depth textbook should be, a superb and vast, yet highly readable review of its topic." Reviewed by glycosmedia.com, Mar 2015 "Principles and Practice of Infectious Diseases has many features and formats that make it a comprehensive, current, and clear source of information" Reviewed by Graefes Arch Clin Exp Ophthalmol, Feb 2015 Get the answers to questions you have with more in-depth coverage of epidemiology, etiology, pathology, microbiology, immunology, and treatment of infectious agents than you'll find in any other infectious disease resource. Find the latest diagnoses and treatments for currently recognized and newly emerging infectious diseases, such as those caused by avian and swine influenza viruses. Put the latest knowledge to work in your practice with new or completely revised chapters on influenza (new pandemic strains); new Middle East respiratory syndrome (MERS) virus; probiotics; antibiotics for resistant bacteria; antifungal drugs; new antivirals for hepatitis B and C; Clostridium difficile treatment; sepsis; advances in HIV prevention and treatment; viral gastroenteritis; Lyme disease; Helicobacter pylori; malaria; infections in immunocompromised hosts; immunization (new vaccines and new recommendations); and microbiome. Benefit from fresh perspectives and global insights from an expanded team of international contributors. Find and grasp the information you need easily and rapidly with newly added chapter summaries. These bulleted templates include diagnosis, therapy, and prevention and are designed as a quick summary of the chapter and to enhance relevancy in search and retrieval on Expert Consult. Stay current on Expert Consult with a thorough and regularly scheduled update program that ensures access to new developments in the field, advances in therapy, and timely information. Access the information you need easily and rapidly with new succinct chapter summaries that include diagnosis, therapy, and prevention. Experience clinical scenarios with vivid clarity through a richly illustrated, full-color format that includes 1500 photographs for enhanced visual guidance.
The contemporary crisis of emerging disease has been a century and a half in the making. Human, veterinary, and crop health practitioners convinced themselves that disease could be controlled by medicating the sick, vaccinating those at risk, and eradicating the parts of the biosphere responsible for disease transmission. Evolutionary biologists assured themselves that coevolution between pathogens and hosts provided a firewall against disease emergence in new hosts. Most climate scientists made no connection between climate changes and disease. None of these traditional perspectives anticipated the onslaught of emerging infectious diseases confronting humanity today. As this book reveals, a new understanding of the evolution of pathogen-host systems, called the Stockholm Paradigm, explains what is happening. The planet is a minefield of pathogens with preexisting capacities to infect susceptible but unexposed hosts, needing only the opportunity for contact. Climate change has always been the major catalyst for such new opportunities, because it disrupts local ecosystem structure and allows pathogens and hosts to move. Once pathogens expand to new hosts, novel variants may emerge, each with new infection capacities. Mathematical models and real-world examples uniformly support these ideas. Emerging disease is thus one of the greatest climate change-related threats confronting humanity. While time is short, the danger is great, and we are largely unprepared, The Stockholm Paradigm offers hope for managing the crisis. By using the DAMA (document, assess, monitor, act) protocol, we can "anticipate to mitigate" emerging disease, buying time and saving money while we search for more effective ways to cope with this challenge.
As the number of surviving immune suppressed patients continues to rise, skin manifestations of patients have become increasingly important. AIDS patients, and renal, heart, liver, bone marrow, and lung transplant patients are now living longer and immunosuppressive drugs are being used more frequently. Diabetes is rising in the US and around the world, offering its own unique brand of immune suppressed skin diseases. The skin may be the earliest sign of these conditions and be the organ showing the most profound, earliest, and treatment limiting side effects. Skin Diseases in the Immunocompromised is the most comprehensive book on the topic available. It elucidates the signs of immune suppressed skin diseases to afford early diagnosis and management of this ever-increasing diverse group of illnesses. Organized for easy access, this book will be an essential resource for residents and fellows in dermatology and infectious diseases medical professionals.
This book provides comprehensive coverage of the current and emerging management of prostatitis, from diagnosis to therapy. It addresses all clinical aspects of the prostatitis syndrome and equips the reader with all the information needed to offer a tailored therapy. Furthermore, clinical implications of the disease are analyzed and discussed, with particular attention to andrological complications (infertility) and the possible link between prostatitis and prostate cancer. Special consideration is also given to contemporary aspects of prostatitis management relating to antibiotic stewardship and elevated PSA, bearing in mind that thoughtless treatment of prostatitis represents malpractice and sometimes even a forensic issue. The final chapter comprising questions and answers will be valuable for quick consultation in everyday clinical practice. This book will be a truly practical guide for physicians involved in the diagnostic work-up and treatment of patients suspected of having prostatitis and will also serve as a ready source of information for all physicians who occasionally see prostatitis patients.
This book presents an historical account of how plagues past and present have shaped the outcome of wars and altered the course of medicine, religion, education, feudalism, and science. Cholera gave birth to the field of epidemiology. The bubonic plague epidemic that began in 1346 led to the formation of universities in cities far from the major centers of learning (and hot spots of the Black Death) at that time. Pathogens are not the only stars of this book. Many scientists and physicians who toiled to treat and prevent these plagues are also featured. This edition also covers modern disease outbreaks, such as anthrax, cholera, Ebola disease, HIV, influenza, Lyme disease, malaria, tuberculosis, and Zika disease, as well as the threat of antimicrobial resistance.
This book provides an in-depth review of knowledge of neurobrucellosis, which remains common despite significant improvements in preventive measures, neuroradiological techniques, and treatment methods. The chapters are organized into five sections, the first three of which address cranial and intracranial brucellosis, spinal brucellosis, and brucellosis of the peripheral portions of the nervous system. The fourth section focuses on laboratory studies in neurobrucellosis, and the closing section is devoted to therapy, encompassing both medical approaches and the surgical procedures used to treat the complications associated with brucellosis involving the spine, brain, and peripheral nerves. Despite the impressive efforts to eradicate the disease, brucellosis still poses a great threat in the Mediterranean Basin, where it originated, as well as in South and Central America, the Caribbean, and Africa. Written and edited by leading international authorities in the field, this comprehensive book will be an ideal up-to-date reference for neurosurgeons, neurologists, and specialists in infectious disease who are seeking either basic or more advanced information on the disease and its diagnosis and treatment.
This handbook is the first dealing with the discovery of drugs directed against apicomplexan parasites. Amongst others, this group of endoparasites includes the causative agents of Malaria, Toxoplasmosis, and Babesiosis, the latter occurring mainly in animals. Written by renowned scientific experts from academia and industry, the book focuses on currentdrug development approaches for all apicomplexan diseases making it appealing to a large audience, ranging from research labs in academia to the human and veterinarian pharmaceutical industry. This work is the second volume of the new book series 'Drug Discovery in Infectious Diseases', edited by Prof. Dr Paul M. Selzer.
The essential guide to controlling and managing today's communicable diseases The fourth edition of Communicable Disease Control and Health Protection Handbook offers public health workers of all kinds an authoritative and up-to-date guide to current protocols surrounding the identification and control of infectious diseases. With its concise, accessible design, the book is a practical tool that can be relied upon to explain topics ranging from the basic principles of communicable disease control to recent changes and innovations in health protection practice. Major syndromes and individual infections are insightfully addressed, while the authors also outline the WHO's international health regulations and the organizational arrangements in place in all EU nations. New to the fourth edition are chapters on Ebola, the Zika virus, and other emerging pandemics. In addition, new writing on healthcare-associated infection, migrant and refugee health, and the importance of preparedness make this an essential and relevant text for all those in the field. This vital resource: Reflects recent developments in the science and administration of health protection practice Covers topics such as major syndromes, control of individual infections, main services and activities, arrangements for all European countries, and much more Includes new chapters on the Zika virus, Schistosomiasis, Coronavirus including MERS + SARS, and Ebola Follows a format designed for ease of use and everyday consultation Created to provide public and environmental health practitioners, physicians, epidemiologists, infection control nurses, microbiologists and trainees with a straightforward - yet informative - resource, Communicable Disease Control and Health Protection Handbook is a practical companion for all those working the field today.
Leprosy (Hansen s disease) is an infectious disease caused by Mycobacterium leprae. It is one of the most disabling disorders in developing countries, with a peak incidence in the tropics and subtropics. With globalization, leprosy is now increasingly spreading to the western world. The impact of this infectious disorder is relevant for the human community due to its transmissible nature, and also important for the individual because of its debilitating consequences. Leprosy is a multifaceted systemic disease with variable presentation and clinical picture. Its identification may therefore not be straightforward, especially outside endemic areas. During its chronic course, leprosy is characterized by acute phases during which there may be exacerbation of symptoms and rapid progression of damage. When leprosy affects the eyes, nerves, and kidneys, it can represent a true medical emergency. The aim of this book is to make the reader familiar with the characteristic signs of disease, including abnormalities of the skin, nerves, eyes, hands, feet, testes, and bone. Early identification of the disease is critical to prevent patient disability and establish appropriate therapy. Emphasis will be given to the current diagnostic tools to identify and quantify the organ damage, including electrophysiology, ultrasonography, magnetic resonance imaging, laboratory tests, and histopathology. Specific topics such as leprosy and pregnancy, leprosy and HIV infection, epidemiology, and leprosy control will also be covered.
The book focuses on the contagion nature of respiratory ailments, the ways a pulmonary disease is spread. Respiratory infections are surrounded by interrelated circumstances that act upon individual and community and eventually underlie morbidity. Patient's age, vulnerability to infections, immune function and responses, comorbidities, but also medical care and the agility in coping with stress, are just a few basic determinants of a diseased state. Modern medication, like newfangled antibiotics and their unrestrained use, may not guarantee the best solution to patient's condition. A valuable asset of this book is a blend of personal experience and expertise of contributors in pursuit of finding new solutions to old clinical problems. The book will be of interest to clinicians, researchers, health care providers, and other health care professionals, particularly those dealing with contagious diseases.
Of the 620,000 soldiers who perished during the American Civil War, the overwhelming majority died not from gunshot wounds or saber cuts, but from disease. And of the various maladies that plagued both armies, few were more pervasive than malaria -- a mosquito-borne illness that afflicted over 1.1 million soldiers serving in the Union army alone. Yellow fever, another disease transmitted by mosquitos, struck fear into the hearts of military planners who knew that "yellow jack" could wipe out an entire army in a matter of weeks. In this ground-breaking medical history, Andrew McIlwaine Bell explores the impact of these two terrifying mosquito-borne maladies on the major political and military events of the 1860s, revealing how deadly microorganisms carried by a tiny insect helped shape the course of the Civil War.
Soldiers on both sides frequently complained about the annoying pests that fed on their blood, buzzed in their ears, invaded their tents, and generally contributed to the misery of army life. Little did they suspect that the South's large mosquito population operated as a sort of mercenary force, a third army, one that could work for or against either side depending on the circumstances. Malaria and yellow fever not only sickened thousands of Union and Confederate soldiers but also affected the timing and success of certain key military operations. Some commanders took seriously the threat posed by the southern disease environment and planned accordingly; others reacted only after large numbers of their men had already fallen ill. African American soldiers were ordered into areas deemed unhealthy for whites, and Confederate quartermasters watched helplessly as yellow fever plagued important port cities, disrupting critical supply chains and creating public panics.
Bell also chronicles the effects of disease on the civilian population, describing how shortages of malarial medicine helped erode traditional gender roles by turning genteel southern women into smugglers. Southern urbanites learned the value of sanitation during the Union occupation only to endure the horror of new yellow fever outbreaks once it ended, and federal soldiers reintroduced malaria into non-immune northern areas after the war. Throughout his lively narrative, Bell reinterprets familiar Civil War battles and events from an epidemiological standpoint, providing a fascinating medical perspective on the war.
By focusing on two specific diseases rather than a broad array of Civil War medical topics, Bell offers a clear understanding of how environmental factors serve as agents of change in history. Indeed, with Mosquito Soldiers, he proves that the course of the Civil War would have been far different had mosquito-borne illness not been part of the South's landscape in the 1860s.
Inside the Hot Zone is an insider's account of one of the most dangerous workplaces on earth: the United States Army Medical Research Institute of Infectious Diseases (USAMRIID) in Fort Detrick, Maryland. Retired U.S. Army Col. Mark G. Kortepeter, a leading biodefense expert, recounts his journey from the lecture hall to the role of department chief, to the battlefield, to the Biosafety Level-4 maximum containment lab, and finally, to the corner office. During Kortepeter's seven and a half years in leadership at USAMRIID, the United States experienced some of the most serious threats in modern germ warfare, including the specter of biological weapons during the Iraq War, the anthrax letters sent after 9/11, and a little-known crisis involving a presumed botulism attack on the president of the United States. Inside the Hot Zone is a shocking, frightening eye-opener as Kortepeter describes in gripping detail how he and his USAMRIID colleagues navigated threats related to anthrax, botulism, smallpox, Lassa, and Ebola. Kortepeter crafts a rich and riveting narrative as he wrestles with life-and-death decisions managing biological weapon exposures. The stories are real, but they could just as easily serve as plotlines in popular fiction or Hollywood thrillers. He gives the reader a seat at the table as each crisis unfolds, with an unvarnished and personal perspective on the dangers, the drama, the fear, the frustrations, the irony, and the uncertainty he encountered as a physician in the role of ""Biodefender.
Today, we are far less likely to die from infection than at any other time in history, but still we worry about epidemics, the menace of antibiotic resistance and modern `plagues' like Ebola. In this timely new book, eminent bacteriologist Hugh Pennington explores why these fears remain and why they are unfounded. He reports on outright victories (such as smallpox), battles where the enemy is on its last stand (polio), surprise attacks from vegetarian bats (Ebola, SARS) and demented cows (BSE). Qualified optimism, he argues, is the message for the future but the battles will go on forever.
Why the news about the global decline of infectious diseases is not all good. Plagues and parasites have played a central role in world affairs, shaping the evolution of the modern state, the growth of cities, and the disparate fortunes of national economies. This book tells that story, but it is not about the resurgence of pestilence. It is the story of its decline. For the first time in recorded history, virus, bacteria, and other infectious diseases are not the leading cause of death or disability in any region of the world. People are living longer, and fewer mothers are giving birth to many children in the hopes that some might survive. And yet, the news is not all good. Recent reductions in infectious disease have not been accompanied by the same improvements in income, job opportunities, and governance that occurred with these changes in wealthier countries decades ago. There have also been unintended consequences. In this book, Thomas Bollyky explores the paradox in our fight against infectious disease: the world is getting healthier in ways that should make us worry. Bollyky interweaves a grand historical narrative about the rise and fall of plagues in human societies with contemporary case studies of the consequences. Bollyky visits Dhaka-one of the most densely populated places on the planet-to show how low-cost health tools helped enable the phenomenon of poor world megacities. He visits China and Kenya to illustrate how dramatic declines in plagues have affected national economies. Bollyky traces the role of infectious disease in the migrations from Ireland before the potato famine and to Europe from Africa and elsewhere today. Historic health achievements are remaking a world that is both worrisome and full of opportunities. Whether the peril or promise of that progress prevails, Bollyky explains, depends on what we do next. A Council on Foreign Relations Book
This book is a major and wide-ranging study of the great epidemic scourges of humanity-plague, leprosy, smallpox, syphilis, cholera, and yellow fever/malaria-over the last six centuries. It will become the standard account of the way diseases arising through chance, through reckless environmental change engineered by man, or through a combination of each were interpreted in Western Europe and in the colonized world. "This trenchant book provides a salutary antidote to world health complacency, past and present."-Roy Porter, The Times (London) "Watts' . . . mastery of six centuries of Western-influenced infectious disease and sanitation history is impressive. He also writes with authority about the pre-modern and modern medical profession."-Claire Panosian, Los Angeles Times Book Review "Watts offers solid, stunning examples of Western idiocy that created superhighways for once-obscure microbes, leading to horrendous epidemics. . . . His is a perspective that Western, particularly Caucasian, policy-makers would do well to comprehend."-Laurie Garrett, Foreign Affairs "The convenience of so much history of diseases in one place is obvious. [An] engrossing book."-Gert Brieger, M.D., New England Journal of Medicine "An important contribution to our understanding of the history of disease, public health, and imperialism."-Suzanne Austin Alchon, American Historical Review
Lyme disease is the most common tick-borne illness in the United States, with more than 300,000 cases diagnosed each year. However, doctors are deeply divided on how to diagnose and treat it, giving rise to the controversy known as the "Lyme Wars." Firmly entrenched camps have emerged, causing physicians, patient communities, and insurance providers to be pitted against one another in a struggle to define Lyme disease and its clinical challenges. Health care providers may not be aware of its diverse manifestations or the limitations of diagnostic tests. Meanwhile, patients have felt dismissed by their doctors and confused by the conflicting opinions and dubious self-help information found online. In this authoritative book, the Columbia University Medical Center physicians Brian A. Fallon and Jennifer Sotsky explain that, despite the vexing "Lyme Wars," there is cause for both doctors and patients to be optimistic. The past decade's advances in precision medicine and biotechnology are reshaping our understanding of Lyme disease and accelerating the discovery of new tools to diagnose and treat it, such that the great divide previously separating medical communities is now being bridged. Drawing on both extensive clinical experience and cutting-edge research, Fallon, Sotsky, and their colleagues present these paradigm-shifting breakthroughs in language accessible to both sides. They clearly explain the immunologic, infectious, and neurologic basis of chronic symptoms, the cognitive and psychological impact of the disease, as well as current and emerging diagnostic tests, treatments, and prevention strategies. Written for the educated patient and health care provider seeking to learn more, Conquering Lyme Disease gives an up-to-the-minute overview of the science that is transforming the way we address this complex illness. It argues forcefully that the expanding plague of Lyme and other tick-borne diseases can be confronted successfully and may soon even be reversed.
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