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This Open Access edition of the European Society for Blood and Marrow Transplantation (EBMT) handbook addresses the latest developments and innovations in hematopoietic stem cell transplantation and cellular therapy. Consisting of 93 chapters, it has been written by 175 leading experts in the field. Discussing all types of stem cell and bone marrow transplantation, including haplo-identical stem cell and cord blood transplantation, it also covers the indications for transplantation, the management of early and late complications as well as the new and rapidly evolving field of cellular therapies. This book provides an unparalleled description of current practices to enhance readers' knowledge and practice skills.
In recent years, considerable progress has been made in understanding the vasculitic diseases, largely due to the introduction of effective treatments for diseases that were once uniformly fatal, the conduct of structured clinical studies, and advances in immunology and molecular biology. Despite these achievements, the vasculitic diseases continue to be associated with morbidity and mortality from chronic organ damage, relapses, and the side effects of treatment. Investigations into the mechanisms of vascular inflammation may lead to a better comprehension of the pathogenesis of vasculitic diseases and to treatment that is more effective and less toxic. These areas of promising research, together with current knowledge about the vasculitic diseases, are extensively examined in this new edition, which is designed to provide a comprehensive overview of the science and clinical consequences of vascular inflammation in health and disease.
Bringing together intellectual and scientific experts from pediatrics, adolescent medicine, general medicine, pathology, biology, nursing and psychology, this book is the first of its kind to cover the topics of leukemias and lymphomas in young patients ranging from infants to young adults. The content is organized and subdivided into four major sections -- under the main headings of General Considerations, Pathobiology, Clinical Manifestations and Treatment, and Supportive Care and Complications -- for ease of reference to readers. Hematological Malignancies in Children, Adolescents and Young Adults presents a comprehensive multidisciplinary review of the field of hematological malignancies and brings forth illuminating perspectives from an internationally recognized group of leading authorities in the field.
Medical Semiology Guide of the Cardiovascular System and the Hematologic System provides a comprehensive understanding of medical semiology in the cardiovascular and hematologic systems. Highly illustrated with many original images from the author's daily medical practice, the book highlights all signs of diseases and important semiological maneuvers in the field. Each chapter incorporates a specific questionnaire with important questions that should be asked to patients in different situations to obtain valuable information that helps identify rare and unusual diseases. This unique feature of the book aims to facilitate the learning process among medical students, while also acting as a quick reference for clinicians.
Hemostasis (coagulation and fibrinolysis) is of importance in a broad range of medical disciplines. A high-quality hemostasis diagnosis enables a good therapy, which can be rather complicated without laboratory help. This yearbook gathers important contributions in this field and presents them in a coherent and logical format.
For more than 65 years, this best-selling text by Drs. Barbara J. Bain, Imelda Bates, and Mike A. Laffan has been the worldwide standard in laboratory haematology. The 12th Edition of Dacie and Lewis Practical Haematology continues the tradition of excellence with thorough coverage of all of the techniques used in the investigation of patients with blood disorders, including the latest technologies as well as traditional manual methods of measurement. You'll find expert discussions of the principles of each test, possible causes of error, and the interpretation and clinical significance of the findings. A unique section on haematology in under-resourced laboratories. Ideal as a laboratory reference or as a comprehensive exam study tool. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices. diagnosis, molecular testing, blood transfusion- and much more. Complete coverage of the latest advances in the field. An expanded section on coagulation now covers testing for new anticoagulants and includes clinical applications of the tests.
The latest edition of this practical handbook provides a concise yet comprehensive overview of common and rare problems with hemostasis and thrombosis. Through thoroughly updated and revised chapters, the text features practical information on diagnosing and managing troublesome hematologic conditions often found in clinical practice. The handbook also spotlights advances in the field since the publication of the last edition, including multiple novel coagulation factors for hemophilia, the increasing use of novel anticoagulants and their reversal agents, and the increasing use of genetics for diagnosis. Written by experts in the field, Hemostasis and Thrombosis, Fourth Edition is an invaluable resource for healthcare professionals who treat patients afflicted with these conditions.
Developed specifically for student nurses and based on the author's over thirty years of teaching experience, Interpreting Arterial Blood Gases the Easy Way teaches students a step-by-step method for interpreting blood gases and helps them learn how to apply the interpretations. The booklet is divided into two parts. Part I teaches students to differentiate between acidic and alkaline states, identify respiratory or metabolic changes in blood gases, and recognize compensated, partially compensated, and uncompensated states. In Part II students apply what they have learned in order to recognize signs and symptoms of abnormal blood gases, identify appropriate interventions, and understand the meaning and significance of specific oxygenation levels. Clear and well-organized, the material features quizzes for self-evaluation, critical thinking questions, and tips that may assist with the National Council Licensure Examination. Knowledge of basic physiology and acid-base balance is recommended before using the booklet, but the information is also reviewed. Interpreting Arterial Blood Gases the Easy Way is an excellent choice for nursing programs. It can also be used in training respiratory therapists and emergency medical technicians.
Blood is vital to most animals. In mammals it transports oxygen and food, carries away waste, and contains the white cells that attack invading microbes. Playing a central role in life, it has had profound cultural and historical significance and plays an important role in religious ritual. Blood was one of the four humours in early Western medicine and is still probably the major diagnostic tool in the doctor's armoury. In this Very Short Introduction, Chris Cooper analyses the components of blood, explains blood groups, and looks at transfusions, blood tests, and blood-borne diseases. He considers what the future may hold, including the possibility of making artificial blood, and producing blood from stem cells in the laboratory. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.
This issue of Hematology/Oncology Clinics, Guest Edited by Drs. Edward Snyder and Eric A. Gehrie, with Consulting Editors George P. Canellos and H. Franklin Bunn, will focus on Transfusion Medicine. Topics include, but are not limited to, Pathogen Reduction, Transfusion Reactions-Infectious Complications, Txn Rxn-Non-Infectious Complications, Iron Deficiency and Teen Blood Donors, Advances in RBC Serology, Advances in Immunotherapy, Therapeutic Monoclonal Antibody Effect on RBC Compatibility Testing, Cell Therapy-New Regulations and Standards, Alternatives to Platelet and RBC Transfusions, New Hemostatic Agents, Tx Practices for Children with Cancer, and Relevance of Cold Platelets and WB to the Bleeding Oncology Patient.
This book is a completely revised new edition of the definitive reference on disorders of hemoglobin. Authored by world-renowned experts, the book focuses on basic science aspects and clinical features of hemoglobinopathies, covering diagnosis, treatment, and future applications of current research. While the second edition continues to address the important molecular, cellular, and genetic components, coverage of clinical issues has been significantly expanded, and there is more practical emphasis on diagnosis and management throughout. The book opens with a review of the scientific underpinnings. Pathophysiology of common hemoglobin disorders is discussed next in an entirely new section devoted to vascular biology, the erythrocyte membrane, nitric oxide biology, and hemolysis. Four sections deal with and thalassemia, sickle cell disease, and related conditions, followed by special topics. The second edition concludes with current and developing approaches to treatment, incorporating new agents for iron chelation, methods to induce fetal hemoglobin production, novel treatment approaches, stem cell transplantation, and progress in gene therapy.
In this book, leaders in the field explore our current understanding of thrombosis and hemostasis in cancer and address key questions on the subject. Among the topics discussed are the mechanisms that cancers use to activate the coagulation system, and those by means of which an activated coagulation system can lead to more aggressive cancer growth. Clinical chapters examine the role of thrombosis prophylaxis and treatment, central line-associated thrombosis, and cancer-associated hemorrhage. Subsequent chapters deal with the management of chemotherapy-induced thrombocytopenia, anticoagulation in the presence of brain metastases, and other unique challenges in the interaction of thrombosis and hemostasis in cancer. It has been 150 years since Armand Trousseau first described the well-known association between cancer and an increased risk of thrombosis, which may be considered the first paraneoplastic syndrome ever identified. More recently, numerous studies have indicated that activation of the coagulation system by cancer not only increases the likelihood of thrombosis, but is also associated with a more aggressive cancer phenotype. By familiarizing readers with the latest developments in this complex and challenging field, the book offers a valuable resource for scientists and clinicians alike.
This book provides a comprehensive overview of the importance of molecular imaging in multiple myeloma, with detailed explanation of its clinical impact. Other important features are the definition of criteria that will aid PET/CT interpretation; identification and explanation of the most frequent pitfalls; a brief overview of the advantages and limitations of DWI MR imaging, still an experimental technique in multiple myeloma; and examination of the possible role of emerging PET tracers. When appropriate, clinical cases are used to illustrate key teaching points. All physicians involved in oncological imaging should regularly reassess and update their routine practice in the evaluation of multiple myeloma patients. This is especially true now, given the recent clarification by the International Myeloma Working Group (IMWG) of the criteria for bone damage requiring therapy and the emerging data supporting the role of the newer functional imaging techniques in predicting outcome and/or evaluating response to therapy. In this challenging context, Molecular Imaging in Multiple Myeloma will be of high value for nuclear medicine physicians, radiologists, and hematologists.
This book is designed not as a comprehensive textbook, but instead as a short practical guide to diagnosis of neoplastic and non-neoplastic diseases of blood, bone marrow, and lymphoid tissues. Concise and easy to read, this text provides essential information in a bulleted text format. This simple format was chosen to provide essential information that may quickly be reviewed at the microscope. Each single-page entry begins with a brief one-line Snapshot description, followed by short descriptions of important clinical, morphologic, immunohistochemical, and genetic features, and ending with Caveats and Pearls and Differential Diagnosis. In most cases, entries are accompanied by a few high-quality histologic images. To keep the text concise, recommended texts and recent review articles are cited in the bibliography at the end of the book. To help quickly find alternative diagnoses, the index cross-references all differential diagnoses. The Pocket Guide to Diagnostic Hematopathology should be of use to practicing hematopathologists (academic and private) and hematologic oncologists, as well as trainees (fellows) in hematopathology and hematologic oncology.
Three books for the price of one--a text, a laboratory procedures manual, and an atlas of cell morphology--all in full color
The tools your students need to quickly master the basic principles of hematology and the fundamentals of hemostasis are here. They'll begin with an introduction to clinical hematology and the anemias, and then progress through white blood cell disorders, and hemostasis to thrombosis, and laboratory methods.
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