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Professor Mary Wingfield is one of Ireland's foremost fertility experts, and she has helped hundreds of people to conceive over the last thirty years. In The Fertility Handbook she has created an up-to-date and authoritative guide for anyone who wants to maximise their chance of pregnancy. This book provides a clear and holistic approach to fertility, including: Understanding your body and maximising your chances of conceiving naturally A pre-conception plan with sections on lifestyle, nutrition and the role of stress The common (and uncommon) causes of fertility problems in both men and women Demystifying complex treatments such as IVF, IUI and egg freezing Up-to-date information on ethics, funding and the law both nationally and internationally Options for single people and same-sex couples from a modern perspective Insightful testimonials from patients dealing with fertility problems and the emotional impact of treatment The Fertility Handbook is a must-read for anyone planning a pregnancy now or in the future. All royalties from the sale of this book will be donated to the Merrion Fertility Foundation, which funds fertility treatment. Mary Wingfield is a leading light in fertility treatment in Ireland for over a generation. If you are looking to know more about maximising your fertility, having a baby or what to do if you're having problems this book is a really good read. Dr Ciara Kelly - Alive and Kicking, Newstalk. 'Wonderfully accessible and hugely informative. Whether seeking or delivering care for infertility, this book will be invaluable'. Dr Rhona Mahony, Master, National Maternity Hospital
How did human thought evolve into the highly complex process it is today? In the field of evolutionary cognitive archaeology, cognitive science and archaeology intersect to provide a more complete and grounded picture of the mind. With the combination of cognitive theories and archaeological evidence, this burgeoning field is only beginning to tap into the potential for a better understanding of the development of specific cognitive abilities. Cognitive Models in Palaeolithic Archaeology explores hominin cognitive development by applying formal cognitive models to analyze prehistoric remains from the entire range of the Palaeolithic, from the earliest stone tools 3.3 million years ago to artistic developments that emerged 50,000 years ago. Several different cognitive models are presented, including expert cognition, information processing, material engagement theory, embodied/extended cognition, neuroaesthetics, visual resonance theory, theory of mind, and neuronal recycling. By examining archaeological remains, and thereby past activities and behavior, through the grounded lenses of these models, a mosaic pattern of human cognitive evolution emerges. This volume, authored by many leading authorities in the field of cognitive archaeology, will attract scholars and students of cognitive evolution and paleoanthropology, who will find a new understanding of hominin cognitive evolution and substantive conclusions about our hominin evolution as opportunities for further research.
Research on testosterone is increasing in many senses; however there is still much controversy regarding its physiology and clinical use. This book addresses these topics, providing a broad over view about testosterone, from its basic fea tures to the most recent evidence of clin ical applicability. Also, specific conditions in which testosterone play a pivotal role are discussed in detail, such as hypogonadism, misuse and abuse, puberty, cardiovascular effects and testosterone therapy. Although not essential for survival, testosterone represents the essence of male biological function, being the important testicular androgen in men. Low serum testosterone levels are asso ciated with cardiovascular morbidity, meta bolic syndrome, type 2 diabetes mellitus, atherosclerosis, osteoporosis, sarcopenia, and mortality. Conversely, increased serum levels of testosterone may lead to deleteri ous events. In general, there is increasing evidence that serum testosterone is a major biomarker status of men's health in general. Testosterone: From Basic to Clinical Aspects is an indispensable reference for all those who seek state-of-the-art knowledge regarding this hormone, from basic issues (including pharma cology and physiology) through clinical aspects (related diseases and supplementation ther apy).
Over the past few decades technological advances in transcriptomics, proteomics, metabolomics, and glycomics along with the ability to selectively knockout genes of interest has greatly advanced our understanding of maternal-conceptus interactions that are essential for the establishment and maintenance of a successful pregnancy. This knowledge provides a foundation from which to build research endeavors to help resolve infertility, embryonic loss and recurrent abortion in humans, captive wild animals and important farm species. The present volume on "Regulation of Implantation and Establishment of Pregnancy in Mammals" brings together current reviews from leading experts to address the diversity of mechanisms by which species establish and maintain pregnancy. Implantation in rodents, dogs, pigs, cattle, sheep, horses, primates, humans and embryonic diapause in wild species are discussed. Reviews will provide current knowledge on the role of endometrial steroid receptors, adhesion factors, cytokines, interferons, steroids, prostaglandins, growth factors and immune cells involved with regulation of conceptus development.
The age-friendly community movement is a global phenomenon, currently growing with the support of the WHO and multiple international and national organizations in the field of aging. Drawing on an extensive collection of international case studies, this volume provides an introduction to the movement. The contributors - both researchers and practitioners - touch on a number of current tensions and issues in the movement and offer a wide-ranging set of recommendations for advancing age-friendly community development. The book concludes with a call for a radical transformation of a medical and lifestyle model of aging into a relational model of health and social/individual wellbeing.
This book provides a comprehensive introduction to various types of perinatal stem cells. Given their unique regenerative abilities, stem cells offer a promising avenue in the treatment of degenerative diseases or injury. Currently, the limitations of postnatal cell sources and expanding efficiency may limit autologous stem cell therapies. Although embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) can be cultured indefinitely ex vivo, and can differentiate into three germ layers, ethical issues, the teratoma formation of ESCs and oncogenic risk of iPSCs are major obstacles to their clinical application. More recently, perinatal stem cells have been isolated from the umbilical cord, Wharton's Jelly, placenta, amniotic membrane and amniotic fluid, which are normally discarded as medical waste. This book, after describing perinatal stem cells in detail, introduces readers to the various types of perinatal stem cells, addressing their characterization, banking, quality control and stability. Importantly, it also reviews the clinical applications of perinatal stem cells to therapy of diseases. Accordingly, it offers a valuable resource for clinicians, researchers and graduate students alike.
In spite of the fact that almost eighty percent of all IVF cycles are unsuccessful, the dominant representations of the technology are of its success. Based on extensive interviews with women and couples who have undergone IVF unsuccessfully and who have since stopped treatment, and taking an overtly feminist approach, the book explores the ways in which IVF failure is experienced and accounted for. The book argues that IVF failure and the end of treatment have to be carefully managed over time in order to construct the self as 'normal' in the profoundly gendered context of reproductive normativity. Treatment failure is identified in the book not only as a central, but largely excluded, aspect of the experience of IVF, but also of a proliferating range of new, more controversial reproductive and genetic technologies.
This volume recognizes the rapidly expanding research linking aging, age-related diseases, and the delicate balance between neurodegeneration and cancer. Wide perspectives on aging are covered, ranging from metabolic and cellular interventions in aging, oxidative stress resistance, protein folding and quality control, as well as the troublesome relationship between prevention of chaperonopathies and the risk for cancer.
Key Features: Explores current research linking aging, age-related diseases, neurodegeneration, and cancer. Includes papers presented at 13th Congress of the Association of Biomedical GerontologyPart of the Annals of the New York Academy of Sciences series
This book is ideal for Graduate students and researchers in the fields of biomedical gerontology, cell and molecular biology, neuroscience, and oncology.
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"ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (""www.nyas.org""). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit" "http: //www.nyas.org/MemberCenter/Join.aspx" "for more information about becoming a member."
The field of infertility research and practice is one of continuous innovation and change, but alongside the increasing sophistication of assisted reproductive techniques there is as strong a need as ever for clinical experience and expertise and common practical sense to inform diagnosis and clinical decision making. Now in its fourth edition, Infertility in Practice is practical and gives the clinician a clear picture of the aetiology of infertility and a careful assessment of the basis for treatment options. A thoroughly comprehensive book that provides sound theory and evidence based therapy, this book is a must for any practitioner dealing with infertility.
This book discusses medicine from an ethical perspective, whereas books on medical ethics more commonly present ethics from a bio-medical standpoint. The book is divided into 23 chapters. The introductory chapters present some basic concepts of medical ethics, such as the relation between the legal system and ethics, ethical documents, ethical theories, and ethical analysis. The following chapters address issues of importance in all fields of medicine: respecting autonomy, communication, relations within a healthcare team, professional malpractice, limited resources, and the portrait of a physician. In turn, the third part of the book focuses on ethical aspects in a broad range of medical activities - preventive medicine, human reproduction, genetics, pediatrics, intensive care, palliative medicine, clinical research, unproven methods in diagnostics and treatment, and the role of physicians who aren't directly responsible for patient care. The last part presents students' seminars with case stories. The book offers a valuable resource for physicians of all specialties, students of medicine, professionals, and students from other fields devoted to human health, journalists, and general readers with an interest in medicine.
This state-of-the-art laboratory manual includes 20 clinical protocols used daily for the investigation of the infertile male, presented with easy to understand, step-by-step methodology. The protocols are arranged from routine to advanced laboratory procedures common to clinical practice, including computer-assisted semen analysis, sperm preparation for IUI by density gradient and swim-up, sperm cryopreservation, and sperm DNA fragmentation test by TUNEL method, among others. The methodology in each protocol follows best practice guidelines made clearer by professionally hand-drawn illustrations covering most of the important steps and equipment. The authors, hailing from the world-renowned Andrology Center at Cleveland Clinic, have over 50 years of combined first-hand experience in managing very busy diagnostic and research facilities in male infertility and andrology. The book will be an indispensable resource for thousands of laboratory technologists, clinicians and reproductive professionals (andrologists, embryologist, etc.) engaged in the diagnosis and management of infertile men around the world.
Now in a revised and expanded second edition, this comprehensive clinical guide remains a state-of-the-art synthesis of the literature, covering all aspects of treating erectile dysfunction (ED) and other related male sexual dysfunctions. Cardiovascular, hormonal, psychological and lifestyle factors are each considered in diagnosis and treatment, which includes pharmacological, surgical and prosthetic management strategies. The effects of prostate cancer and its treatment are also discussed, as are Peyronie's disease, priapism and ejaculatory disorders. New chapters in this edition discuss the profound effects of lifestyle change on sexual function, alternative and internet drugs that affect sexual function, endovascular approaches to ED, penile length considerations, the effect of radiation on erectile function, and optimizing ED research. Presenting a better understanding of what causes erectile dysfunction and the effective medications and non-medication treatments used to treat the condition, this invaluable title offers all physicians, residents, and fellows - and even medical students and other health professionals such as nurse practitioners and physician assistants - an essential reference for enhancing diagnosis and treatment of this common and debilitating disorder.
One of the problems geriatricians are confronted with in everyday clinical practice is differentiating disease from the process of old age. The challenges of ageing require a better understanding of the essential biology of ageing in order to separate ageing from disease, and indeed ageing made worse by disease. Although the topic is large and diverse, this practical and easy-to-read reference book contains vital information on the biology of ageing. It provides a concise understanding of the changes that occur and focuses on the clinical implications of ageing. MCQs are featured throughout for revision and examination practice. The Biology of Ageing provides the reader with: . a learning guide on the biology of ageing through an overview of the changes that occur at both cellular and system levels . knowledge of how biological changes of ageing impact on physiology and the clinical relevance in medical practice . a practical consideration of these changes in disease presentations and how these changes may impact on disease management. This full-colour guide featuring slides, MRIs, figures and photographs is ideal for doctors training in geriatric medicine, practising geriatricians and those with an interest in management of older people.
World-wide migration has an unsettling effect on social structures, especially on aging populations and eldercare. This volume investigates how taken-for-granted roles are challenged, intergenerational relationships transformed, economic ties recalibrated, technological innovations utilized, and spiritual relations pursued and desired, and asks what it means to care at a distance and to age abroad. What it does show is that trans-nationalization of care produces unprecedented convergences of people, objects and spaces that challenge our assumptions about the who, how, and where of care.
The fourth edition of "Human Reproductive Biology" emphasizes
the biological and biomedical aspects of human reproduction,
explains advances in reproductive science and discusses the choices
and concerns of today. Generously illustrated in full color, the
text provides current information about human reproductive anatomy
and physiology. This expansive text covers the full range of topics
in human reproduction, from the biology of male and female systems
to conception, pregnancy, labor and birth. It goes on to cover
issues in fertility and its control, population growth and family
planning, induced abortion and sexually transmitted diseases. This
is the ideal book for courses on human reproductive biology, with
chapter introductions, sidebars on related topics, chapter
summaries and suggestions for further reading.
Sammelband mit Beitragen von 28 Expertinnen und Experten aus dem Bereich der assistierten Reproduktion. Immer haufiger werden Verfahren der medizinisch assistierten Reproduktion genutzt, die den Beitrag Dritter einschliessen, also Samenspende, Eizellspende, Embryospende oder Leihmutterschaft. Diese Formen der Familienbildung mit Hilfe Dritter werfen ein breites Spektrum an medizinischen, ethischen, rechtlichen und lebensweltlichen Fragen auf, die umfassend und im interdisziplinaren Kontext diskutiert werden sollten. In diesem Sammelband mit Beitragen in deutscher und englischer Sprache diskutieren Expertinnen und Experten aus unterschiedlichen fachlichen und lebensweltlichen Perspektiven Probleme und Loesungsansatze. Empirische Analysen aus der internationalen Forschung und Praxisbeispiele aus Grossbritannien, USA, Australien und Neuseeland erganzen die Darstellung.
This book offers a cutting-edge guide to hysteroscopy and provides readers with the latest and most essential information on procedure techniques, clinical advances and international developments in practice and treatment of endometrial pathology. Providing comprehensive coverage, it explains in detail every aspect of hysteroscopy, from diagnostics to hysteroscopic surgery. As such, it addresses the bases of hysteroscopy; pre-, intra- and post-hysteroscopy medications; intracavitary pathologies; fertility issues; and surgical implications and complications. At the same time, it also explores challenging and controversial topics, such as hysteroscopy and ART, submucous myomas, and uterine malformations. All topics are discussed by prominent experts in the field, and clearly organized and illustrated to help readers gain the most from each chapter. Accordingly, the book offers a valuable resource for all gynecologists working at hysteroscopy units, reproductive units, gynecological and oncological units, as well as a quick reference guide for all other physicians interested in the topic.
No current book tells the clinician how to handle a patient with infertility and abnormal semen analysis who arrives in front of him or her in the infertility clinic. The time is right for a new book that looks at the clinical aspects of this subject only and which is directed specifically at the clinicians. One must remember that the majority of clinicians that treat male infertility are gynaecologists who, unlike the author have had no training whatsoever in urology. The problem of examining let alone treating the infertile man is therefore very daunting.
This unique compilation focuses on a very curious organ, the ovary. There are still many unknown facts about the origins of ovarian tissue and ovarian cancer, and each chapter describes in detail the latest insights into the ovary from basic to clinical aspects. Expert authors reveal the most recent findings on ovariogenesis and ovarian carcinogenesis by shedding light on stem cell biology for the ovarian surface epithelial cells or primordial germ cells. Readers will greatly increase their understanding of the relevance of the cells that constitute the ovary, which is of vast significance in comprehending the occurrence mechanism of ovarian tissue and ovarian cancer. In this way the book covers a wide range of fields concerned with the ovary. This work benefits not only gynecologists and obstetricians, but also basic researchers in the field of stem cell biology and all clinicians who are involved in the management of fertility preservation or ovarian cancer.
The over-arching goal of this volume is to help infertility practitioners evaluate and manage their patients with poor semen quality. The authors review the existing literature on the effects of medications on male fertility, and provide detailed information about what is known, giving the number of individuals and population characteristics for studies of medication effects on male fertility. Medications are designed to treat illness and reduce symptoms, but all have undesirable adverse effects such as headache or stomach upset. Some adverse reactions can even be life-threatening, so it is no surprise that some drugs have negative effects on male reproduction. Medical practitioners rarely consider a man's reproductive plans when prescribing medications. Men are routinely treated with drugs that can impair or abolish fertility. Although practitioners in the field of reproductive medicine generally realize that certain drugs impact negatively on reproductive health, there are limited resources providing evidence-based knowledge useful in counseling patients. Tables throughout this volume summarize the information for each drug, providing a handy reference for clinical use.
This book is on ovulation induction and controlled ovarian stimulation which is an integral part of most infertility therapies like intrauterine insemination and in vitro fertilization. It would deal with causes of anovulation and indications for ovarian stimulation. This book deals with basics as well as current and advanced practices. It provides a step by step protocol for ovarian stimulation. It gives a clear understanding of the science of reproductive endocrinology behind these stimulation protocols and roadmaps the latest therapies, defining their current relevance to treatment. Besides the practical guidance it also covers latest research work done in this field. In this day of information overload it is an attempt to integrate relevant information in a manner which can be applied in infertility practice in evidence based manner, making it rational, logical and rewarding for the reader.
Child development refers to the biological and psychological changes that occurs in human beings between birth and the end of adolescence, as the individual progress from dependency to increasing autonomy. Developmental change may occur as a result of genetically-controlled process known as maturation, or as a result of environmental factors and learning, but most commonly it involves an interaction between the two. One of the most relevant aspects in the socio-economic progress in the developing countries is the development of children. Children are the future resource of a country and thus its supreme assets. The optimal development of children is considered vital to society and so it is important to understand their social, cognitive, emotional and educational development. The early development of cognitive skills, emotional well- being, social competence, and sound physical and mental health builds a strong foundation for success well in to the adult years. Beyond their short term importance for positive school achievement, theses abilities are critical prerequisites for economic productivity and responsible citizenship throughout life. All aspects of adult human capital, from workforce skills to co-operative and lawful behaviour are build capacities which are development during childhood beginning at birth. This book begins with an overview of child development. The focus of the book is to explore the idea of child development in terms of the various component of child development, namely nutrition, health, education etc., And to evaluate the progress of child development in the developing world.
This new book reviews the latest advances in the embryology, genetics, diagnosis, imaging, and therapy of congenital heart disease. The international cast of authors has combined its talents to produce a unique, expert perspective. This publication arrives at a very exciting time when new genetic, imaging, and therapeutic developments are changing the field. It is relevant to pediatricians, internal medicine specialists, medical geneticists, both pediatric and adult cardiologists, embryologists, imaging physicians, and cardiac surgeons. The reader is taken on a journey that begins with a historical overview of congenital cardiovascular anomalies and ends with developments in stem cell and tissue engineering. In between are chapters on cardiac embryogenesis; epidemiology; genetic syndromes associated with cardiovascular anomalies; single gene disorders; cardiac imaging; surgical and interventional therapies; and ethical considerations. 'Congenital Heart Disease' is an invaluable reference. In short, it provides essential information to create a comprehensive resource for all physicians involved with the diagnosis and treatment of cardiac malformations.
In the mid-1990s, the international community pronounced prenatal sex selection via abortion an "act of violence against women" and "unethical." At the same time, new developments in reproductive technology in the United States led to a method of sex selection before conception; its US inventor marketed the practice as "family balancing" and defended it with the rhetoric of freedom of choice. In Gender before Birth, Rajani Bhatia takes on the double standard of how similar practices in the West and non-West are divergently named and framed. Bhatia's extensive fieldwork includes interviews with clinicians, scientists, biomedical service providers, and feminist activists, and her resulting analysis extends both feminist theory on reproduction and feminist science and technology studies. She argues that we are at the beginning of a changing transnational terrain that presents new challenges to theorized inequality in reproduction, demonstrating how the technosciences often get embroiled in colonial gender and racial politics.
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