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What happens when a baby is born with "ambiguous" genitalia or a combination of "male" and "female" body parts? Clinicians and parents in these situations are confronted with complicated questions such as whether a girl can have XY chromosomes, or whether some penises are "too small" for a male sex assignment. Since the 1950s, standard treatment has involved determining a sex for these infants and performing surgery to normalize the infant's genitalia. Over the past decade intersex advocates have mounted unprecedented challenges to treatment, offering alternative perspectives about the meaning and appropriate medical response to intersexuality and driving the field of those who treat intersex conditions into a deep crisis. Katrina Karkazis offers a nuanced, compassionate picture of these charged issues in "Fixing Sex," the first book to examine contemporary controversies over the medical management of intersexuality in the United States from the multiple perspectives of those most intimately involved.
Drawing extensively on interviews with adults with intersex conditions, parents, and physicians, Karkazis moves beyond the heated rhetoric to reveal the complex reality of how intersexuality is understood, treated, and experienced today. As she unravels the historical, technological, social, and political forces that have culminated in debates surrounding intersexuality, Karkazis exposes the contentious disagreements among theorists, physicians, intersex adults, activists, and parents--and all that those debates imply about gender and the changing landscape of intersex management. She argues that by viewing intersexuality exclusively through a narrow medical lens we avoid much more difficult questions. Do gender atypical bodies require treatment? Should physicians intervene to control the "sex" of the body? As this illuminating book reveals, debates over treatment for intersexuality force reassessment of the seemingly natural connections between gender, biology, and the body.
People are living into old age. This is actually a revolutionary
statement as we look back to the start and then to the end of the
twentieth century. This demographic revolution raises important
practical and ethical issues and, for the most part, has led the
way for the field of gerontology, the study of aging, to emerge as
an area of increasing importance. With that in mind, Thorson has
revised and expanded his 1995 text to serve as an introduction to
the multidisciplinary field of gerontology.
Biopolitics and posthumanism have been passe theories in the academy for a while now, standing on the unfashionable side of the fault line between biology and liberal thought. These days, if people invoke them, they do so a bit apologetically. But, as Ruth Miller argues, we should not be so quick to relegate these terms to the scholarly dustbin. This is because they can help to explain an increasingly important (and contested) influence in modern democratic politicsthat of nostalgia. Nostalgia is another somewhat embarrassing concept for the academy. It is that wistful sense of longing for an imaginary and unitary past that leads to an impossible future. And, moreover for this book, it is ordinarily considered bad for democracy. But, again, Miller says, not so fast. As she argues in this book, nostalgia is the mode of engagement with the world that allows thought and life to coexist, productively, within democratic politics. Miller demonstrates her theory by looking at nostalgia as a nonhuman mode of thought, embedded in biopolitical reproduction. To put this another way, she looks at mass democracy as a classically nonhuman affair and nostalgic, nonhuman reproduction as the political activity that makes this democracy happen. To illustrate, Miller draws on the politics surrounding embryos and the modernization of the Turkish alphabet. Situating this argument in feminist theories of biopolitics, this unusual and erudite book demonstrates that nostalgia is not as detrimental to democratic engagement as scholars have claimed.
This book provides andrologists and other practitioners with reliable, up-to-date information on all aspects of male infertility and is designed to assist in the clinical management of patients. Clear guidance is offered on classification of infertility, sperm analysis interpretation and diagnosis. The full range of types and causes of male infertility are then discussed in depth. Particular attention is devoted to poorly understood conditions such as unexplained couple infertility and idiopathic male infertility, but the roles of diverse disorders, health and lifestyle factors and environmental pollution are also fully explored. Research considered stimulating for the reader is highlighted, reflecting the fascinating and controversial nature of the field. International treatment guidelines are presented and the role of diet and dietary supplements is discussed in view of their increasingimportance. Clinicians will find that the book s straightforward approach ensures that it can be easily and rapidly consulted."
"Tissue Morphogenesis: Methods and Protocols "highlights major techniques, both experimental and computational, for the study of tissue morphogenesis, divided into several sections, with specific focus on techniques to image, manipulate, model and analyze tissue morphogenesis. Chapters focus on imagining analysis of tissue morphogenesis, culture models of tissue morphogenesis, manipulating cells and tissues in vivo, novel model systems to investigate issue morphogenesis and computational models. Written in the highly successful "Methods in Molecular Biology "series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical," ""Tissue Morphogenesis: Methods and Protocols" serves as a primary resource for both fundamental and practical understanding of the techniques used to uncover the basis of tissue morphogenesis.
The male and female reproductive systems consist of the gonads, testes or ovaries; the reproductive tract; the external genitalia; and the hypothalamic-pituitary unit. The functions of the reproductive system are to produce and deliver gametes, spermatozoa or oocytes, for sexual reproduction; and produce hormones that regulate reproductive function and secondary sex characteristics. Abnormalities in anatomic or physiologic function affect the development and delivery of gametes, and potential fertility. This book provides a comprehensive review of the anatomy and physiology specific to reproduction, emphasizing developmental and hormonal processes of gamete production, fertilization, implantation, and embryonic development. This review has been designed to meet the educational needs of physicians and allied health professionals who care for couples experiencing infertility. By developing a clear understanding of what is normal, you will better understand abnormalities affecting reproduction and the mechanisms behind treatment.
Why Can't I Get Pregnant? If this is the painful question you have been asking yourself lately, I am sorry for your situation but there is HOPE This book will help you learn about what will most likely be your next step, Invitro fertilization and what its all about You will hear from others who have gone through the IVF process and has come out on the other side with a beautiful addition to their family. Some of what you will learn includes: What is IVF The STEP BY STEP process of IVF (you are walked through everything ) Choosing the right medical facility Ways to AFFORD IVF that most don't want you to know State coverage laws And MUCH MORE Throughout this report, commonly asked questions and answers are presented in addition to insider's tips and personal experiences. In vitro fertilization is an important decision facing many couples today. For some, it is their last hope. For others, it is a costly, hopeless, dream. Researching IVF is a careful and lengthy process for all. The objectives of this report are to supply readers with current and concise facts about IVF, minimizing the research process on the reader's part, and providing them with information which will help each couple to make their own personal decision regarding IVF and fertility treatment. Get Your Copy Today "
The state of our understanding of each single step of human reproduction is presented in this volume, which also looks at the ongoing research aiming to improve human reproductive efficiency.
Invited chapters focus on the field of endometrial preparation for embryonization, trophoblast capability to implant into maternal endometrial tissue, and evidence-based medicine to improve embryos' implantation and reduce recurrent abortion.
A report on human reproduction efficiencies through assisted reproductive technologies is presented as a review by both Europeans and Americans.
Among the major issues explored in this volume is the pelvic
factor of sterility, endometriosis, miomas, and their medical and
surgical treatments according to the principles of evidence-based
medicine and evidence-based surgery.
Surgical management of reproductive organs using the most up-to-date techniques is also be reported on, and particular attention is given to stem cells in gametes and embryonic stem cells.
"NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas."
"ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http: //www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member"
The purpose of this book is to help those who are struggling to become pregnant for whatever reason. Starting a family is a big decision and most of us expect it to happen pretty quickly. But what if it doesn't? What should we do next when we have tried for a year and nothing has happened? Many people assume the next step is IVF but this is only one option in a vast line of options available and is certainly not right for everyone. Many of you who were labelled "infertile" will be able to become pregnant naturally by following a few simple steps outlined in this book. Jessica will take you through a logical process of understanding your own body and reproductive system. It is amazing how little we were taught at school about our reproductive health and our body's normal fertility signals. This book will cover male and female fertility separately- how to optimise naturally fertility in both men and women, how to read the body's fertile signals, tests which may be required, and if there is a problem, the appropriate solutions which are available. This book will also cover the psychology of trying to get pregnant, the truth about ageing and fertility, miscarriages and dealing with loss, and assisted reproductive technologies. There is progress all the time in the world of fertility and conception and it is important you understand what these options are and when they are right for you. This will allow you to assist your medical team in getting a solution that you all want- a healthy baby. One of the most stressful things about entering the world of infertility is the feeling of lack of control, feeling like you are on a treadmill of tests and procedures and feeling more and more resentment towards all your friends who are announcing their pregnancies. There is a lot of information out there- some of it is confusing, some of it is contradictory and some of it is misleading. This book pulls together the latest research in one place in a logical way that you can understand so you know what you need to do next to get a successful pregnancy. Some of you will be able to become pregnant naturally without any intervention by making a few very simple changes. Others may need some assistance but you will know much more clearly what you need and the logical steps to follow. Trying to get pregnant can be overwhelming; knowledge is power- grab this book and take back control of your life
Ovulation induction and controlled ovarian stimulation lie at the very heart of treatment for infertility, but have been subject to a bewildering variety of variations and improvements over recent years. The Second Edition of this highly successful book updates the reader on the progress and developments in this area. Furthermore, it provides the busy clinician with a reliable overview of the principles involved and the management needed. As with the previous edition, the emphasis throughout this book is on logical evidence and evidence-based solutions supplemented with Professor Homburg's extensive clinical experience gleaned from more than forty years working in the field. A number of highly useful algorithms and explanatory tables reinforce this approach, ensuring that the reader is presented with easy-to-grasp, well-presented information that maximizes clarity and understanding. This book offers a concise, no-nonsense, practical guide to ovulation induction and controlled ovarian stimulation and will be an essential resource for the general gynaecologists, fertility specialists and trainees, health workers and students.
The present Maharashtra Human Development Report (MHDR) 2012 keeps the spirit of the Eleventh and Twelfth Five Year Plans of 'faster, sustainable and more inclusive growth' at the core of its analysis. MHDR 2002 was the state's first effort in focusing on the prevailing human development scenario in the spheres of growth, poverty, equity, education, health and nutrition. Since then the state has come a long way in the last decade, achieving near-complete enrolments at the primary school level, a wide coverage of health infrastructure and initiation of new incentives, to name a few. The 2012 Report goes beyond being just a situation-analysis of the current human development scenario to a more analytical exercise in facilitating a deeper understanding of what and where the inequalities are, how capabilities can be enhanced, what has been the progress, where the shortfalls are and where the thrust of efforts to promote human development should be. Recognizing the centrality of inclusive growth processes to human development, the need to study human development outcomes disaggregated by gender, rural-urban, regional and social groups is the focal point of this Report. The outcome would be the identification of specific human development goals, evidence-based policy recommendations and directions to how those excluded from the growth and human development processes can be included to reap the benefits of the same.
THE SUNDAY TIMES BESTSELLER Izzy Judd shares the story of her and her husband Harry's fertility journey in this honest and heartfelt memoir. 'All I ever wanted was to be a mum - I couldn't wait and it felt as though my time was so close. But the months started to tick by, with each one ending in disappointment and frustration. And then the inevitable panic started to set in ...' Having been told by doctors that, due to Izzy's polycystic ovarian syndrome, they would have difficulty conceiving - and after two years of trying - Izzy and Harry turned to IVF. Izzy's aim, drawing on her own experience, is to break through some of the taboos surrounding miscarriage, IVF and fertility issues. This brutally honest and deeply personal account will acknowledge the struggles that so many couples go through but will ultimately focus on the positive, life-changing and remarkable results that IVF can yield. One in seven couples in the UK have difficulty conceiving and although many babies are now born through IVF, there is still a sense of awkwardness around the subject. Izzy hopes that this book will be a companion to those going through similar challenges to those she has experienced. As she herself says, 'No couple should have to go through it alone and in silence.'
Fertility Preservation: Advances and Controversies is a practical guide to fertility preservation techniques in patients undergoing therapy that may damage reproductive organs, such as chemotherapy and radiation therapy. Divided into two sections, the first part provides in depth discussion on different fertility preservation approaches in females, and the second part examines male fertility preservation. Written by an extensive author and editor team from Canada, the USA and Europe, this concise guide includes detailed algorithms, and numerous images, illustrations and tables. Key points Practical guide to fertility preservation in patients undergoing therapy affecting reproductive organs Examines techniques for both female and male fertility preservation Extensive, internationally recognised author and editor team Includes numerous algorithms, images, diagrams and tables
A candid assessment of the pros and cons of delayed motherhood.
This addition to the Springer Brief in Stem Cells series focuses on aspects related to the specific mechanisms that ensure and control pluripotency and cell commitment in domestic animal species. This topic is generating rapidly-increasing interest due to the great potential for domestic animal species to be used as intermediate biomedical models, between the mouse and the human. The Brief addresses why we need large animal models for regenerative medicine. It also describes early embryo development with a careful and specific analysis of the regulatory mechanisms driving cleavage, polarization and genome activation in domestic species. How pluripotency is compartmentalized in domestic species as well as the different aspects that make the derivation of stem cells in domestic species very difficult are also addressed.
The advent of robotic surgery brought a rise in the proportion of minimally invasive surgery in gynecology. This book provides a practical guide to this innovative field. First it introduces the basics of robotic surgery and then focuses on specific gynecology-related surgeries. Gynecologists currently practicing robotic surgery as well as those who would like to include robotic surgery in their practice will benefit greatly from this book.
This second edition has been extensively revised to bring clinicians fully up to date with the latest technologies and advances in the field of assisted reproductive techniques (ART). Each section is dedicated to a sub specialty, from polycystic ovary syndrome, ART procedures, and laboratory issues, to implantation, cryopreservation, endoscopy, ultrasound and more. A section entitled `contemporary thoughts' examines the improvement of IVF outcome, ART and older women, and HIV and ART, and another discusses third party reproduction. Edited by internationally recognised experts in reproductive medicine, this comprehensive guide is highly illustrated with clinical photographs and diagrams to enhance learning. Previous edition (9781841844497) published in 2004. Key points Fully revised, second edition providing latest advances in ART Complete section dedicated to third party reproduction Highly experienced, internationally recognised editor and author team Previous edition (9781841844497) published in 2004
Fertility preservation has become one of the most important and fast growing fields of reproductive medicine. Although there are several strategies for fertility preservation in female, most of them are still considered experimental. It is important to perfect the existing technologies, but also developing new strategies should be actively sought. The future development of fertility preservation strategies should be based on the sound scientific knowledge and principles. One of the main objectives of fertility preservation in females is prevention of oocyte depletion. The mechanisms of oocyte loss and survival in the ovary are complex, which include genetic control both in germ cells and in somatic cells, DNA damage and repair mechanism, apoptosis and autophagy, and other poorly understood molecular mechanisms. To develop clinically effective and safe strategies for fertility preservation, it is essential to know and understand the fundamentals of oocyte and ovarian biology at the molecular level. Thus, the purpose of this edition is to review the current progress in research related to molecular and genetic control of oocyte development that can be applied to fertility preservation. The main topics that are discussed in this publication include molecular signaling mechanisms of oocyte activation and loss, genomic integrity of oocytes, and epigenetics. "
This concise, truncated version of Nagy, Varghese and Agarwal's Practical Manual of In Vitro Fertilization is comprised of select clinical chapters for a portable, affordable and up-to-date resource. Gamete Assessment, Selection and Micromanipulation in ART covers a variety of topics, including: - Human oocyte evaluation - Sperm evaluation and selection - Micromanipulators and micromanipulation - Biopsy procedures on oocytes and embryos - Molecular insights in IVF Practical for both clinicians and researchers alike, Gamete Assessment, Selection and Micromanipulation in ART brings together all of the need-to-know information about these important topics in reproductive medicine.
This book addresses the impacts of current and future reproductive technologies on our world food production and provides a significant contribution to the importance of research in the area of reproductive physiology that has never been compiled before. It would provide a unique opportunity to separate the impacts of how reproductive technologies have affected different species and their contributions to food production. Lastly, no publication has been compiled that demonstrates the relationship between developments in reproductive management tools and food production that may be used a reference for scientists in addressing future research areas. During the past 50 years assisted reproductive technologies have been developed and refined to increase the number and quality of offspring from genetically superior farm animal livestock species. Artificial insemination (AI), estrous synchronization and fixed-time AI, semen and embryo cryopreservation, multiple ovulation and embryo transfer (MOET), in vitro fertilization, sex determination of sperm or embryos, and nuclear transfer are technologies that are used to enhance the production efficiency of livestock species.
This concise, truncated version of Parekattil and Agarwal's "Male Infertility: Contemporary Clinical Approaches, Andrology, ART & Antioxidants" is the first resource dedicated solely to antioxidants and male infertility. With select chapters that will prove invaluable to the practitioner of reproductive medicine, "Antioxidants in Male Infertility" addresses issues such as:
- Molecular mechanisms of antioxidants in male infertility
- Oxidative stress
- The impact of infection, aging, obesity, and injury on male infertility
- Natural and synthetic antioxidants and antioxidant therapy
- Antioxidants in ICSI and IMSI
Also included is a new chapter reviewing the physiological role of reactive oxygen species in sperm function.
Practical for clinicians and researchers alike, "Antioxidants in Male Infertility" contains all of the need-to-know information about these cutting-edge topics in reproductive medicine.
The first IVF conceived birth in 1978 resulted in a significant growth of third party reproductive options which continue to raise ethical, legal, and psychological questions. Third party reproduction procedures can involve as many as five people: sperm donor, egg donor, gestational carrier, and intended parents. "Third-Party Reproduction: A Comprehensive Guide" utilizes experts in the field to address the medical, psychological, ethical and legal aspects of sperm donation, egg donation, embryo donation, and the use of gestational carriers. In addition, there are chapters on the medical and ethical aspects of posthumous reproduction, religious aspects of third party reproduction, and how to avoid pitfalls of third party reproduction. Aimed at physicians, trainees, psychologists, nurses, and social workers whose practices may include patients considering third party reproduction, the intent of this book is to provide a comprehensive and practical overview of the many aspects of third party reproduction to help all those involved to better understand them. Patients considering third party reproduction may also find value in this book.
Presenting an overview of the current understanding of the pathophysiology of PCOS and a paradigm for the clinical evaluation and management of the disorder, "Polycystic Ovary Syndrome "is written in an easy to digest, concise format that, with bulleted key points introducing each chapter, is suitable for the trainee and the busy clinician. The breadth and depth of coverage of today s queries and controversies will be of particular interest to the specialist and researcher. An international group of leading experts addresses the varied etiologies of PCOS, comprehensively covering the contemporary treatment approaches and long-term implications of PCOS, a common yet poorly understood disorder. Chapters on treatment will be of particular relevance to the clinician and the trainee as they cover conventional therapies, lifestyle, and diet, as well as address emerging strategies such as the use of statins and surgery in PCOS management.
Spanning the breadth of clinical presentations and morbidities related to the diagnosis of PCOS, "Polycystic Ovary Syndrome "is an exceptional resource for primary care providers, gynecologists, reproductive endocrinologists, and others involved in the care of these patients, and provides the essential tools to aid clinicians in initiating a timely diagnostic workup and appropriate interventions to address both the immediate and long-term sequelae related to PCOS.
The population-health-environment approach to development recognizes the interconnectedness between people and their environment, and this book examines the issues therein while identifying areas of further research and action. Population growth, size, fertility, mortality, migration, settlement patterns, and resource availability all influence the environment and development; solving the associated complex challenges demands a better understanding of how these aspects of population impact the environment, how environmental changes impact our health and well-being, and what can be done to address these issues. If these aspects can be successfully and effectively integrated, then a range of development goals, from poverty reduction to health security to gender equity, can be achieved. The papers in this volume provide comprehensive analysis by utilizing the most recent data and information.
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