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An ideal text for the natural product scientist looking for new techniques in research, this volume comprises the latest information on natural/plant resources.The comprehensive chapters cover the chemistry and pharmacology of a range of natural products - from Chinese herbal medicine to tea extracts, microbes to marine sponges, and the latest technologies to enhance the synthesis, isolation and purification of bioactive herbal compounds from these products. Adding additional value to the book are chapters on new tools in information technology that can greatly facilitate the research of natural product scientists, and the technologies available for evaluating medicinal herbal products for purity.
SHORTLISTED FOR THE 2018 BAILLIE GIFFORD PRIZE FOR NON-FICTION
She Has Her Mother’s Laugh presents a profoundly original perspective on what we pass along from generation to generation. Charles Darwin played a crucial part in turning heredity into a scientific question, and yet he failed spectacularly to answer it. The birth of genetics in the early 1900s seemed to do precisely that. Gradually, people translated their old notions about heredity into a language of genes. As the technology for studying genes became cheaper, millions of people ordered genetic tests to link themselves to missing parents, to distant ancestors, to ethnic identities . . .
But, award-winning science writer Carl Zimmer argues, heredity isn’t just about genes that pass from parent to child. Heredity continues within our own bodies, as a single cell gives rise to trillions of cells that make up our bodies. We say we inherit genes from our ancestors but we inherit other things that matter as much or more to our lives, from microbes to technologies we use to make life more comfortable. We need a new definition of what heredity is and, through Carl Zimmer’s lucid exposition and storytelling, this resounding tour de force delivers it.
Weaving together historical and current scientific research, his own experience with his two daughters, and the kind of original reporting expected of one of the world’s best science journalists, Zimmer ultimately unpacks urgent bioethical quandaries arising from new biomedical technologies, but also long-standing presumptions about who we really are and what we can pass on to future generations.
This new series presents innovative titles pertaining to human origins, evolution, and behavior from a multi-disciplinary perspective. Subject areas include but are not limited to biological and physical anthropology, prehistoric archaeology, evolutionary psychology, behavioral ecology, and evolutionary biology. The series volumes will be of interest primarily to students and scholars in these fields.
Until twenty years ago we had no idea which of our genes came from our father and which came from our mother. We took it for granted that our genes expressed themselves identically and that there was a 50/50 chance that they came from either parent. We also assumed that they worked in cooperation with each other. The biggest breakthrough in genetics in the past two decades has been the discovery of genomic imprinting, which allows us to trace genes to the parent of origin. David Haig has been at the forefront of theorizing these developments arguing that these "paternally and maternally active genes" comprising less than one percent of our total gene count are far from being cooperative, and have in fact been shown to be in competition with one another. If Haig's theory is correct, imprinted genes provide an extraordinary example of within-individual conflict, which is one of the most surprising developments in evolutionary biology in recent years. Examples like this are shaking up our fundamental ideas of what it means to be an individual.
This collection of Haig's papers provides a unique comprehensive overview of what is known. Each paper is followed by a commentary that links it to the others, provides background as needed, and brings readers up-to-date on developments thatoccurred after the paper's original publication. Because genomic imprinting raises questions across various fields in the life sciences, including evolutionary biology and developmental genetics, Haig's work is scattered through the literature to an unusual degree, and has never been collected in one volume.
The Pacific Symposium on Biocomputing (PSB) 2017 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2017 will be held on January 4 - 8, 2017 in Kohala Coast, Hawaii. Tutorials and workshops will be offered prior to the start of the conference.PSB 2017 will bring together top researchers from the US, the Asian Pacific nations, and around the world to exchange research results and address open issues in all aspects of computational biology. It is a forum for the presentation of work in databases, algorithms, interfaces, visualization, modeling, and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology.The PSB has been designed to be responsive to the need for critical mass in sub-disciplines within biocomputing. For that reason, it is the only meeting whose sessions are defined dynamically each year in response to specific proposals. PSB sessions are organized by leaders of research in biocomputing's 'hot topics.' In this way, the meeting provides an early forum for serious examination of emerging methods and approaches in this rapidly changing field.
A concise, clear writing style and a detailed and rich coverage of topics are the reasons that students found the first edition of the book so engaging and useful.Riding on this wave, all chapters within the second edition of this popular book have been thoroughly updated and expanded, especially the human and animal materials. A wider range of animals is covered, including dogs and cats as well as farm animals. The use of cord blood for therapy, pre-implantation genetic diagnosis and animal cloning are also explored and dealt with.
THE NEW YORK TIMES NUMBER ONE BESTSELLER Spanning the globe and several centuries, this is the remarkable story of the gene and an intimate history of the author's own family, from award-winning author Siddhartha Mukherjee The story begins in an Augustinian abbey in 1856, and takes the reader from Darwin's groundbreaking theory of evolution, to the horrors of Nazi eugenics, to present day and beyond - as we learn to "read" and "write" the human genome that unleashes the potential to change the fates and identities of our children. Majestic in its scope and ambition, The Gene provides us with a definitive account of the epic history of the quest to decipher the master-code that makes and defines humans - and paints a fascinating vision of both humanity's past and future. "Siddhartha Mukherjee is the perfect person to guide us through the past, present, and future of genome science' Bill Gates `A thrilling and comprehensive account of what seems certain to be the most radical, controversial and, to borrow from the subtitle, intimate science of our time...Read this book and steel yourself for what comes next' Sunday Times
** THE PERFECT STOCKING FILLER FOR YOUR FAVOURITE SCIENCE NERD. ** Part of the ALL-NEW LADYBIRD EXPERT SERIES. ____________ Who discovered genetics? How does gene inheritance work? Is DNA common to all living things? We inherit CODES from our parents. And these codes are written in the molecule DNA. This DNA means that we RESEMBLE each other, namely our families. This raises so many questions such as how does DNA influence evolution? How was it discovered? And what does it mean for the future of the human race? Discover the answers and more inside Adam Rutherford's Ladybird Expert - Genetics, the thrilling and accessible account that explains race and genetics, whether it is our DNA or the environment that influences us most, what are our chances of being related to royalty, genetic engineering and much more . . .
"We are buried beneath mountains of fast-accumulating data. In such circumstances, this book, rather than adding to the data load, aims to offer real understanding." -James Lovelock Human beings are extraordinary creatures. Intelligent, agile, and curious, we have adapted and invented our way to becoming the most important species on the planet. So great is the extent of our influence, that many speak of a new geological era, the Anthropocene, an age defined by human-induced change to the blue and green globe we call home. Our lofty status comes with responsibility as much as possibility: How should we approach our present and future? What knowledge should we carry with us? Conceived by James Lovelock, inventor of the Gaia theory, this illustrated essay collection brings together an all-star lineup of thinkers and scientists to offer essential understanding about who we are, how we live, and where we might be going. Much as the Gaia theory considers our Earth as an integrated whole of living systems, The Earth and I encourages holistic understanding. Across 12 chapters, we take in both the intricate details and immense structures of our species and our planet, from our ever-expanding universe to our minuscule but mighty cells. We see stellar explosions and the layers of life beneath our feet, delve into the neuroscience of decision-making, get to grips with our climate, and contemplate our increasing intimacy with technology. The book's world-class contributors include quantum physicist Lisa Randall, Astronomer Royal Martin Rees, Pulitzer Prize-winning biologist Edward O. Wilson, and Nobel Prize-winning neuroscientist Eric Kandel. With lively illustrations from British artist Jack Hudson, the result is an inspiration for curious minds young and old, and a trusted tool kit for an informed and enlightened future.
Colours are increasingly important in our daily life, but how did colour vision evolve? How have colours been made, used and talked about in different cultures and tasks? How do various species of animals see colours? Which physical stimuli allow us to see colours and by which physiological mechanisms are they perceived? How and why do people differ in their colour perceptions? In answering these questions and others, this book offers an unusually broad account of the complex phenomenon of colour and colour vision. The book's broad and accessible approach gives it wide appeal and it will serve as a useful coursebook for upper-level undergraduate students studying psychology, particularly cognitive neuroscience and visual perception courses, as well as for students studying colour vision as part of biology, medicine, art and architecture courses.
This comprehensive book about the lives of bats is about a group of peculiar, mythical and fascinating animals. They are mammals, just like us, but still so different. The book covers bats from Latin American Maya temples to Swedish potato cellars; from the plains of Kenya to the Taiwanese mountains. We perceive their shadows flitting by in the summer nights, hear their mating calls in the darkness of autumn and see their silhouettes in the dim street light. The bats live in our houses and forage in our gardens and parks. But who are they and how do they lead their lives? The text and exquisite photos give an unsurpassed insight into the world of sounds and smells that bats encounter each night. We are told about how their senses, way beyond our human perception abilities, shape their lives. We get to know more about their habits, their long evolution and their cohabitation with humans, and how important they are to the environment. You will never again feel lonely in the darkness of the night.
There is a growing crisis in our oceans as rates of infectious disease outbreaks are on the rise. Marine epidemics have the potential to cause a mass die-off of wildlife from the bottom to the top of the food chain, impacting the health of ocean ecosystems as well as lives on land. Fueled by sewage dumping, unregulated aquaculture, and drifting plastic in warming seas, ocean outbreaks are sentinels of impending global environmental disaster. Ocean Outbreak follows renowned scientist Drew Harvell and her colleagues as they investigate how four iconic marine animals--corals, abalone, salmon, and starfish--have been devastated by disease. Based on over twenty years of research, this firsthand account of the sometimes creeping, sometimes exploding impact of disease on our ocean's biodiversity ends with a hopeful message. Through policy changes and the implementation of innovative solutions from nature, we can reduce major outbreaks, save some ocean ecosystems, and protect our fragile environment.
Learn all about how your DNA makes you who you are-an awesome, unique individual-in this fun and simple illustrated guide! Did you know your sense of purpose is determined by your genes? And that DNA determines your reaction to poison ivy, and maybe even your sex drive? In DNA Is You!, the author behind Beatrice the Biologist uses her trademark humor to break down the ins and outs of DNA to give you the low-down on each trait, one by one. She provides the answers to questions like: how dependent are traits on your parents' genes? Are they based on mutations or influenced by the environment? What kind of studies have been performed on genetics, and what have they discovered? Home DNA tests are more popular than ever, and DNA Is You! takes a look at the weird and wild scientific factors that can change your genes-like that dimples are dominant, how someone gets two different eye colors, and which genes determine whether or not you'll need glasses. Learn more about how you got to be who you are with DNA Is You! and understand yourself-and your family-a little bit better!
As read by James Corden, Fearne Cotton, Jim Chapman and Dougie Poytner. 'We have a responsibility, every one of us' David Attenborough Around 12.7 million tonnes of plastic are entering the ocean every year, killing over 1 million seabirds and 100,000 marine mammals. By 2050 there could be more plastic in the ocean than fish by weight. Plastic pollution is the environmental scourge of our age, but how can YOU make a difference? This accessible guide, written by the campaigner at the forefront of the anti-plastic movement, will help you make the small changes that make a big difference, from buying a reusable coffee cup to running a clean-up at your local park or beach. Tips on giving up plastic include: * Washing your clothes within a wash bag to catch plastic microfibers (the cause of 30% of plastic pollution in the ocean) * Replacing your regular shampoo with bar shampoo * How to lobby your supermarket to remove unnecessary packaging * How to throw a plastic-free birthday party * How to convince others to join you in giving up plastic Plastic is not going away without a fight. We need a movement made up of billions of individual acts, bringing people together from all backgrounds and all cultures, the ripples of which will be felt from the smallest village to the tallest skyscrapers. This is a call to arms - to join forces across the world and to end our dependence on plastic. #BreakFreeFromPlastic Plastic is not going away without a fight. We need a movement made up of billions of individual acts, bringing people together from all backgrounds and all cultures, the ripples of which will be felt from the smallest village to the tallest skyscrapers. 'Plastic waste is one of the greatest environmental challenges facing the world' Theresa May 'As Head of Oceans at Greenpeace, Will is on the front line of humanity's global fight against plastic. This timely book not only explains how we got into this mess, but most importantly offers an optimistic and proactive approach as to how we can get out of it'. - Richard Walker, Managing Director at Iceland
Vast numbers of different prokaryotic microorganisms shape the biosphere, with diverse metabolic capabilities. Determination of genome sequences for a wide range of bacteria and archaea now requires an in-depth knowledge of prokaryotic metabolic function to give biochemical, physiological and ecological meaning to the genomic information. This new edition describes up-to-date knowledge of the key metabolic processes that occur under different conditions, and the cellular processes that determine prokaryotic roles in the environment, biotechnology and human health. Essential for students of microbiology, applied microbiology, biotechnology, genomics and systems biology, this advanced textbook covers prokaryotic structure, composition, nutrient transport, biosynthesis and growth. Newly characterised metabolic pathways are included, as well as the latest understanding of metabolic regulation and stress responses. Additionally, the link between energetics, growth and survival is discussed as well as the maintenance of genetic integrity by the bacterial immune system.
Why do giraffes have such long necks? Why are zebras striped? Why are buffalo herds broadly democratic while elephants prefer dictatorships? What explains the architectural brilliance of the termite mound or the complications of the hyena's sex life? And why have honey-badgers evolved to be one of nature's most efficient agents of mass destruction?
Deploying the latest scientific research and his own extensive observations on the African savannah, Lťo Grasset offers some answers to these and many other intriguing questions. Having shown that natural phenomena are rarely simple and that often they get more complex the more you look at them, he brings to bear a mix of evolutionary biology and lateral thinking to explain the mysteries of animal behaviour in terms that are simple but never simplifying. He ends by considering how our origins in the savannah and evolution as the hybrid of several species can shapes our habits.
Lťo Grasset is one of France's brightest young natural scientists. Prepare to be fascinated, delighted, surprised, shocked and, above all, entertained by his brilliantly original Darwinian Just So stories.
The first volume in the new Cambridge Handbooks in Behavioral Genetics series, Behavioral Genetics of the Mouse provides baseline information on normal behaviors, essential in both the design of experiments using genetically modified or pharmacologically treated animals and in the interpretation and analyses of the results obtained. The book offers a comprehensive overview of the genetics of naturally occurring variation in mouse behavior, from perception and spontaneous behaviors such as exploration, aggression, social interactions and motor behaviors, to reinforced behaviors such as the different types of learning. Also included are numerous examples of potential experimental problems, which will aid and guide researchers trying to troubleshoot their own studies. A lasting reference, the thorough and comprehensive reviews offer an easy entrance into the extensive literature in this field, and will prove invaluable to students and specialists alike.
PATTERNS OF LIFE: SPECIAL EDITIONS OF GROUNDBREAKING SCIENCE BOOKS When the eminent naturalist Charles Darwin returned from South America on board the HMS Beagle in 1836, he brought with him the notes and evidence that would form the basis of a world-changing theory: the evolution of species by a process of natural selection. This theory, published as On the Origin of Species in 1859, is the basis of modern biology and the concept of biodiversity. Its publication sparked a fierce scientific, religious and philosophical debate which continues to this day.
** THE PERFECT STOCKING FILLER FOR AN INQUISITIVE MIND. ** Part of the new Ladybird Expert series, Evolution is a clear, simple and entertaining introduction to Charles Darwin's pioneering and revolutionary theory of how all life changes through natural selection. Written by broadcaster, prize-winning author and geneticist Professor Steve Jones, it explores the extraordinary diversity of life on our planet through the complex interactions of one very simple theory. You'll discover the common origins of dogs and Brussels sprouts, how it is we're all mutants, where wings, ears and tails came from, why sex is good for you, how some dinosaurs evolved and survived, and why human evolution may finally have stopped. Written by the leading lights and most outstanding communicators in their fields, the Ladybird Expert books provide clear, accessible and authoritative introductions to subjects drawn from science, history and culture. Other books currently available in the Ladybird Expert series include: * Climate Change * Quantum Mechanics For an adult readership, the Ladybird Expert series is produced in the same iconic small hardback format pioneered by the original Ladybirds. Each beautifully illustrated book features the first new illustrations produced in the original Ladybird style for nearly forty years.
Plant remains can preserve a critical part of history of life on Earth. While telling the fascinating evolutionary story of plants and vegetation across the last 500 million years, this book also crucially offers non-specialists a practical guide to studying, dealing with and interpreting plant fossils. It shows how various techniques can be used to reveal the secrets of plant fossils and how to identify common types, such as compressions and impressions. Incorporating the concepts of evolutionary floras, this second edition includes revised data on all main plant groups, the latest approaches to naming plant fossils using fossil-taxa and techniques such as tomography. With extensive illustrations of plant fossils and living plants, the book encourages readers to think of fossils as once-living organisms. It is written for students on introductory or intermediate courses in palaeobotany, palaeontology, plant evolutionary biology and plant science, and for amateurs interested in studying plant fossils.
Bringing order and relevance to the cascade of recent brain findings, Dr John Ratey explains the brainís most important systems, the role they play in determining how we interact with the world and ways in which we can influence their operations for the better. Throughout, he illustrates his points with vivid and often surprising examples drawn from his own practice, research and everyday life. Ratey answers such compelling questions as: What does it mean to be linguistically ambidextrous? How does a motherís cradling of her child on her left shoulder relate to the development of language skills? Why does listening to music while doing homework improve accuracy? Why do people like spicy foods? He also analyses the ways in which things can go wrong, detailing causes and treatments for diseases such as autism, Parkinsonís and Alzheimerís, as well as numerous neurological disorders. As Dr. Ratey demonstrates throughout the book, the brain is astonishingly flexible, able to be retrained and reprogrammed. Like a muscle, it responds to use, adapting to new demands and conditions, allowing, as the title of the book suggests, the guidance of the user.
What we do and do not know about evolution, by one of the field's pioneering thinkers. Evolution is the most important idea in biology, with implications that go far beyond science. But despite more than a century's progress in understanding, there is still widespread confusion about what evolution is, how it works and why it is the only plausible mechanism that can account for the remarkable diversity of life on Earth. Now, for the first time in a book aimed at a general audience, one of the founding fathers of modern biology tells us what we know - and what we do not know - about evolution. In showing how evolution has gone from theory to fact, he explores various controversial fads and fallacies such as punctuated equilibrium, the selfish-gene theory and evolutionary psychology. He ends by looking at what we know about human evolution and how, in turn, this knowledge has affected the way in which we view ourselves and the world.
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