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Books > Medicine > General issues > Medical equipment & techniques

Medical Instrumentation - Application and Design (Hardcover, 4th Edition): John G. Webster Medical Instrumentation - Application and Design (Hardcover, 4th Edition)
John G. Webster
R5,347 Discovery Miles 53 470 Ships in 10 - 15 working days

This book provides biomedical engineers with the premiere reference on medical instrumentation as well as a comprehensive overview of the basic concepts. The revised edition features new material on infant apnea monitors, impedance pneumography, the design of cardiac pacemakers, and disposable defibrillator electrodes and their standards. Each chapter includes new problems and updated reference material that cover the latest medical technologies. The chapters have also been revised with new material in medical imaging, providing biomedical engineers with the most current techniques in the field.

Fundamentals of research methodology for healthcare professionals (Paperback, 4th ed): C. van der Walt, H.I. Brink, G. Van... Fundamentals of research methodology for healthcare professionals (Paperback, 4th ed)
C. van der Walt, H.I. Brink, G. Van Rensburg
R378 R319 Discovery Miles 3 190 Save R59 (16%) Ships in 4 - 8 working days
Overkill - When Modern Medicine Goes Too Far (Hardcover): Paul A. Offit Overkill - When Modern Medicine Goes Too Far (Hardcover)
Paul A. Offit
R675 R532 Discovery Miles 5 320 Save R143 (21%) Ships in 7 - 11 working days
Theoretical Basis for Nursing (Paperback, Fifth, International Edition): Melanie McEwen, Evelyn M. Wills Theoretical Basis for Nursing (Paperback, Fifth, International Edition)
Melanie McEwen, Evelyn M. Wills
R1,444 Discovery Miles 14 440 Ships in 10 - 15 working days

Now in its 5th edition, Wolters Kluwer's AJN Award Winning text,Theoretical Basis for Nursing , provides an overview of nursing theory that includes the essential information that a student needs to understand theory and its application to practice. Students-with little to no knowledge of nursing theory-will gain insight into how theory can affect their practice and make them better nurses. In Unit I, Students are ushered through the skills needed to develop, analyze, and evaluate theory for use in their careers. This skill set will help students pursuing all potential career paths-in nursing practice, research, administration, management, and/or education. As a unique focus in Unit II, grand theories are discussed in relation to 1) human needs, 2) interactive process, and 3) unitary process. This unit provides the perfect amount of information-just enough for the reader to 1) understand the basis of the work and 2) become enticed enough in the material to want to select one or two theories for primary source study. Also, because of an emphasis on middle range theory in nursing programs, the authors present an overview of selected middle range theories, examining their origins and growth. The broad range of middle range theories sampled will point students in the right direction to search for others appropriate to their practice. Some NEW! theories to this edition include aerohemodynamic theory, transtheoretical model of change, and the precede/proceed model. In Unit II, there will be an enhanced discussion of Evidence-based practice (EBP) and nursing theory. As its next frontier, nursing theory will increasingly focus on EBP protocols, and McEwen & Wills help students understand the inter-relatedness of theory, research, and practice. This edition includes an enhanced discussion of the history of EBP and practice-based evidence (PBE). In Unit III, students explore "shared theories," benefitting from the body of knowledge that can be distilled from other disciplines. This unit is unique to this text, and students will discover stories of how nurses have used shared theories in their own practice. In this edition, a NEW! chapter called "Ethical Theories and Principles" will be included in this unit. The text concludes with Unit IV, a summary of how theories should be and are applied in nursing. Functioning as a practical guide, separate chapters cover nursing practice, nursing research, nursing administration and management, and nursing education. The evolving development of practice theories and importance of evidence-based practice guidelines are critical to theory application in nursing today. NEW! In our application to practice chapter (Chapter 19), we will add examples of the theoretical underpinnings related to the clinical practice guidelines. Reinforcing its emphasis on practice, both the book and its resources on thePoint will include case studies with examples from nursing in general through advanced practice scenarios. Because Nursing Theory is often a reading and writing intensive course, this text comes with a Scholarly Writing in Nursing: Best Practices. This resource covers the basics of APA as well as good writing principles, and it also provides weblinks to additional resources. This edition will also feature improved indices making content in the text easier to find quickly. This text is accompanied by a robust instructor resource package featuring an Instructor's Guide, Case Studies with supportive curriculum, PowerPoints, and more. Theoretical Basis for Nursing, 5th Edition offers an inspiring message to readers to contribute to the ongoing development, application, analysis, and evaluation of concepts, principles, theories, and models to advance the discipline of nursing. According to authors McEwen & Wills, "As the health profession with the largest number of providers, nursing has the greatest potential to have the greatest impact on health and healthcare delivery."

Molecular Diagnostics (Paperback): Anthony Warford, Nadege Presneau Molecular Diagnostics (Paperback)
Anthony Warford, Nadege Presneau
R1,063 Discovery Miles 10 630 Ships in 10 - 15 working days

One of the most notable trends in biomedical science in recent years has been the increasing use of molecular techniques as part of the diagnosis of disease. As such, there is a growing need for students to understand the technological basis of molecular analysis and to have a comprehensive appreciation of their use in diagnosis. Combining coverage of molecular techniques with their application to diagnostic pathology, this book provides students with a thorough and up to date appreciation of the scope of molecular analysis, the principles of the technology used, and thematic diagnostic application. As part of the Fundamentals of Biomedical Science series, the book provides a unique blend of theory and practice, featuring a range of learning features to help students assimilate the information presented quickly and effectively. It will be relevant to undergraduate students on a wide variety of biomedical pathways, cutting across traditional discipline boundaries to provide a unified overview of molecular diagnostics.

MATLAB - A Practical Introduction to Programming and Problem Solving (Paperback, 5th edition): Stormy Attaway MATLAB - A Practical Introduction to Programming and Problem Solving (Paperback, 5th edition)
Stormy Attaway
R1,449 R1,308 Discovery Miles 13 080 Save R141 (10%) In stock

MATLAB: A Practical Introduction to Programming and Problem Solving, winner of TAA's 2017 Textbook Excellence Award ("Texty"), guides the reader through both programming and built-in functions to easily exploit MATLAB's extensive capabilities for tackling engineering and scientific problems. Assuming no knowledge of programming, this book starts with programming concepts, such as variables, assignments, and selection statements, moves on to loops, and then solves problems using both the programming concept and the power of MATLAB. The fifth edition has been updated to reflect the functionality of the current version of MATLAB (R2018a), including the addition of local functions in scripts, the new string type, coverage of recently introduced functions to import data from web sites, and updates to the Live Editor and App Designer.

The Fatal Sleep (Paperback, 3rd New edition): Peter Kennedy The Fatal Sleep (Paperback, 3rd New edition)
Peter Kennedy
R305 R242 Discovery Miles 2 420 Save R63 (21%) Ships in 10 - 15 working days

The bite of the tsetse fly - a burning sting into the skin - causes a descent into violent fever and aching pains. Severe bouts of insomnia are followed by mental deterioration, disruption of the nervous system, coma and ultimately death. Sleeping sickness, also known as Human African trypanosomiasis, is one of Africa's major killers. It puts 60 million people at risk of infection, occurs in 36 countries in sub-Saharan Africa, and claims the lives of many thousands of people every year. Transmitted by the tsetse fly, trypanosomiasis affects both humans and cattle. The animal form of the disease severely limits livestock production and farming, and in people the toxic effects of the treatment for the brain disease can be as painful and dangerous as the disease itself. Existing in the shadow of malaria and AIDS, it is an overlooked disease, ignored by pharmaceutical companies and largely neglected by the western world. Peter Kennedy has devoted much of his working life to researching sleeping sickness in Africa, and his autobiographical account shares not only his trials and experiences, evoking our empathy with the affected patients, but an explanation of the disease, including its history and its future. Interwoven with African geography, his compassionate story reveals what it is like to be a young doctor falling in love with Africa, and tells of his building of a vocation in the search for a cure for this cruel disease.

Advances in Salivary Diagnostics (Hardcover): Charles F. Streckfus Advances in Salivary Diagnostics (Hardcover)
Charles F. Streckfus
R3,486 R2,647 Discovery Miles 26 470 Save R839 (24%) Ships in 10 - 15 working days

This book reviews the progress made in salivary diagnostics during the past two decades and identifies the likely direction of future endeavors. After an introductory section describing the histological and anatomical features of the salivary glands and salivary function, salivary collection devices and diagnostic platforms are reviewed. The field of "salivaomics" is then considered in detail, covering, for example, proteomics, the peptidome, DNA and RNA analysis, biomarkers, and methods for biomarker discovery. Salivary diagnostics for oral and systemic diseases are thoroughly discussed, and the role of salivary gland tissue engineering for future diagnostics is explored. The book closes by considering legal issues and barriers to salivary diagnostic development. Advances in Salivary Diagnostics will be an informative and stimulating reference for both practitioners and students.

Human histology (Paperback): H.L. Coetzee, G.P. Loots Human histology (Paperback)
H.L. Coetzee, G.P. Loots
R685 R587 Discovery Miles 5 870 Save R98 (14%) Ships in 7 - 10 working days

In this publication, description of the basic histology tissues is followed by a description of the histology of the different organs and systems in the human. The subject contents is presented on a relevant clinical level, and students in both medicine and dentistry, as well as related health professions, such as nursing, occupational therapy and physiotherapy, will find it simple and meaningful. The terminology used in the publication correlates with the writing style used as standard in English medical, dental and health care science' schools.

The Dark Art of Blood Cultures (English, Chinese, Paperback): Michael Dunne Jr., Carey-Ann D. Burnham The Dark Art of Blood Cultures (English, Chinese, Paperback)
Michael Dunne Jr., Carey-Ann D. Burnham
R1,453 R1,325 Discovery Miles 13 250 Save R128 (9%) Ships in 10 - 15 working days

Understanding the diagnostic methods necessary to identify bloodstream infections. In the clinical microbiology laboratory, blood is a critical diagnostic sample that, in the majority of cases is sterile (or is it?). However, when microbes gain access to and multiply in the bloodstream, it can result in life-threatening illness including sepsis. Mortality rates from bloodstream infection and sepsis range from 25% to 80%, killing millions of people annually. Blood cultures are a vital technology used in the microbiology laboratory to isolate and identify microbes and predict their response to antimicrobial therapy. The Dark Art of Blood Cultures, edited by Wm. Michael Dunne, Jr., and Carey-Ann D. Burnham, surveys the entire field of blood culture technology, providing valuable information about every phase of the process, from drawing samples to culture methods to processing positive cultures. The Dark Art of Blood Cultures is organized around several major topics.

How to Read a Paper - The Basics of Evidence-based Medicine and Healthcare (Paperback, 6th Edition): Trisha Greenhalgh How to Read a Paper - The Basics of Evidence-based Medicine and Healthcare (Paperback, 6th Edition)
Trisha Greenhalgh
R840 Discovery Miles 8 400 Ships in 10 - 15 working days

Required reading in many medical and healthcare institutions, How to Read a Paper is a clear and wide-ranging introduction to evidence-based medicine and healthcare, helping readers to understand its central principles, critically evaluate published data, and implement the results in practical settings. Author Trisha Greenhalgh guides readers through each fundamental step of inquiry, from searching the literature to assessing methodological quality and appraising statistics. How to Read a Paper addresses the common criticisms of evidence-based healthcare, dispelling many of its myths and misconceptions, while providing a pragmatic framework for testing the validity of healthcare literature. Now in its sixth edition, this informative text includes new and expanded discussions of study bias, political interference in published reports, medical statistics, big data and more. Offers user-friendly guidance on evidence-based healthcare that is applicable to both experienced and novice readers Authored by an internationally recognised practitioner and researcher in evidence-based healthcare and primary care Includes updated references, additional figures, improved checklists and more How to Read a Paper is an ideal resource for healthcare students, practitioners and anyone seeking an accessible introduction to evidence-based healthcare.

Bad Pharma - How Medicine is Broken, and How We Can Fix it (Paperback): Ben Goldacre Bad Pharma - How Medicine is Broken, and How We Can Fix it (Paperback)
Ben Goldacre 1
R337 R218 Discovery Miles 2 180 Save R119 (35%) Ships in 10 - 15 working days

'Bad Science' hilariously exposed the tricks that quacks and journalists use to distort science, becoming a 400,000 copy bestseller. Now Ben Goldacre puts the $600bn global pharmaceutical industry under the microscope. What he reveals is a fascinating, terrifying mess. Doctors and patients need good scientific evidence to make informed decisions. But instead, companies run bad trials on their own drugs, which distort and exaggerate the benefits by design. When these trials produce unflattering results, the data is simply buried. All of this is perfectly legal. In fact, even government regulators withhold vitally important data from the people who need it most. Doctors and patient groups have stood by too, and failed to protect us. Instead, they take money and favours, in a world so fractured that medics and nurses are now educated by the drugs industry. The result: patients are harmed in huge numbers. Ben Goldacre is Britain's finest writer on the science behind medicine, and 'Bad Pharma' is the book that finally prompted Parliament to ask why all trial results aren't made publicly available - this edition has been updated with the latest news from the select committee hearings. Let the witty and indefatigable Goldacre show you how medicine went wrong, and what you can do to mend it.

Comprehensive Healthcare Simulation: Mastery Learning in Health Professions Education (Paperback, 1st ed. 2020): William C.... Comprehensive Healthcare Simulation: Mastery Learning in Health Professions Education (Paperback, 1st ed. 2020)
William C. McGaghie, Jeffrey H. Barsuk, Diane B. Wayne
R2,947 Discovery Miles 29 470 Ships in 7 - 11 working days

This book presents the parameters of Mastery Learning (ML), an especially stringent variety of competency-based education that guides students to acquire essential knowledge and skill, measured rigorously against a minimum passing standard (MPS). As both a scholarly resource and a teaching tool, this is a "how to" book that serves as a resource for a wide variety of health professions educators. A seminal source of information and practical advice about ML, this book divided into five parts: Clinical Education in the Health Professions, The Mastery Learning Model, Mastery Learning in Action, Transfer of Training from Mastery Learning and The Road Ahead. Complete with high-quality images and tables, chapters take an in-depth look into ML principles and practices across the health professions. Specific educational content instructs readers on how to build and present ML curricula, evaluate short and long-run results, conduct learner debriefing and give powerful feedback, set learner achievement standards, and prepare faculty for new educational roles. An invaluable addition to the Comprehensive Healthcare Simulation Series, Mastery Learning in Health Professions Education is written and edited by leaders in the field for practicing clinicians in a variety of health professions.

Data Monitoring Committees in Clinical Trials - A Practical Perspective (Hardcover, 2nd Edition): Susan S. Ellenberg, Thomas R.... Data Monitoring Committees in Clinical Trials - A Practical Perspective (Hardcover, 2nd Edition)
Susan S. Ellenberg, Thomas R. Fleming, David L. DeMets
R2,433 R2,188 Discovery Miles 21 880 Save R245 (10%) Ships in 10 - 15 working days

The authoritative guide for Data Monitoring Committees--fully revised and updated The number of clinical trials sponsored by government agencies and pharmaceutical companies has grown in recent years, prompting an increased need for interim monitoring of data on safety and efficacy. Data Monitoring Committees (DMCs) are an essential component of many clinical trials, safeguarding trial participants and protecting the credibility and validity of the study. Data Monitoring Committees in Clinical Trials: A Practical Perspective, 2nd Edition offers practical advice for those managing and conducting clinical trials and serving on Data Monitoring Committees, providing a practical overview of the establishment, purpose, and responsibilities of these committees. Examination of topics such as the composition and independence of DMCs, statistical, philosophical and ethical considerations, and determining when a DMC is needed, presents readers with a comprehensive foundational knowledge of clinical trial oversight. Providing recent examples to illustrate DMC principles, this fully-updated guide reflects current developments and practices in clinical trial oversight and offers expanded coverage of emerging issues and challenges in the field. This new second edition covers the most current information on DMC policies, issues in monitoring trials using new designs, and recent trial publications relevant to DMC decision-making. - Presents practical advice for those managing and conducting clinical trials and serving on Data Monitoring Committees - Illustrates the types of challenging issues Data Monitoring Committees face in practical situations - Provides updated and expanded coverage of topics including regulatory and funding agency guidelines and trial designs and their associated demands and limitations - Includes a new chapter addressing legal issues that affect DMC members and discusses general litigation concerns relevant to clinical research - Expands treatment of current journal publications addressing DMC issues Data Monitoring Committees in Clinical Trials: A Practical Perspective, 2nd Edition is a must-have text for anyone engaged in DMC activities as well as trial sponsors, clinical trial researchers, regulatory and bioethics professionals, and those associated with clinical trials in academic, government and industry settings.

ABC of Quality Improvement in Healthcare (Paperback): Tim Swanwick, Emma Vaux ABC of Quality Improvement in Healthcare (Paperback)
Tim Swanwick, Emma Vaux
R1,038 Discovery Miles 10 380 Ships in 7 - 11 working days

Quality improvement (QI) is embedded in the fabric of successful healthcare organisations across the world, with healthcare professionals increasingly expected to develop and lead improvement as a core part of their clinical responsibilities. As a result, QI is rapidly becoming a feature of the education and training programmes of all healthcare professionals. Written and edited by some of the leading clinicians and managers in the field, ABC of Quality Improvement is designed for clinicians new to the discipline, as well as experienced leaders of change and improvement. Providing comprehensive coverage and clear, succinct descriptions of the major tools, techniques and approaches, this new addition to the ABC series demystifies quality improvement and develops a broader understanding of what constitutes quality in healthcare. With practical examples of improvement interventions and the common pitfalls that can befall them, this book will support and enable readers to manage change projects within their own organisations. Relevant to doctors, dentists, nurses, health service managers and support staff, medical students and doctors in training, their tutors and trainers, and other healthcare professionals at various levels, ABC of Quality Improvement will give readers the confidence to embark on their own improvement projects, whoever, and wherever they may be.

Microbiology (Loose-leaf): Burton Leboffe Microbiology (Loose-leaf)
Burton Leboffe
R2,587 Discovery Miles 25 870 Ships in 7 - 11 working days
Behavioral Genetics of the Mouse: Volume 1, Genetics of Behavioral Phenotypes (Hardcover, New): Wim E. Crusio, Frans Sluyter,... Behavioral Genetics of the Mouse: Volume 1, Genetics of Behavioral Phenotypes (Hardcover, New)
Wim E. Crusio, Frans Sluyter, Robert T. Gerlai, Susanna Pietropaolo
R3,242 R2,989 Discovery Miles 29 890 Save R253 (8%) Ships in 10 - 15 working days

The first volume in the new Cambridge Handbooks in Behavioral Genetics series, Behavioral Genetics of the Mouse provides baseline information on normal behaviors, essential in both the design of experiments using genetically modified or pharmacologically treated animals and in the interpretation and analyses of the results obtained. The book offers a comprehensive overview of the genetics of naturally occurring variation in mouse behavior, from perception and spontaneous behaviors such as exploration, aggression, social interactions and motor behaviors, to reinforced behaviors such as the different types of learning. Also included are numerous examples of potential experimental problems, which will aid and guide researchers trying to troubleshoot their own studies. A lasting reference, the thorough and comprehensive reviews offer an easy entrance into the extensive literature in this field, and will prove invaluable to students and specialists alike.

WHO classification of tumours of the breast (Paperback, 5th ed): S.R. Lakhani, International Agency for Research on Cancer WHO classification of tumours of the breast (Paperback, 5th ed)
S.R. Lakhani, International Agency for Research on Cancer
R4,378 Discovery Miles 43 780 Ships in 7 - 11 working days
Medical Statistics from Scratch - An Introduction for Health Professionals (Paperback, 4th Edition): David Bowers Medical Statistics from Scratch - An Introduction for Health Professionals (Paperback, 4th Edition)
David Bowers
R975 Discovery Miles 9 750 Ships in 10 - 15 working days

Correctly understanding and using medical statistics is a key skill for all medical students and health professionals. In an informal and friendly style, Medical Statistics from Scratch provides a practical foundation for everyone whose first interest is probably not medical statistics. Keeping the level of mathematics to a minimum, it clearly illustrates statistical concepts and practice with numerous real-world examples and cases drawn from current medical literature. Medical Statistics from Scratch is an ideal learning partner for all medical students and health professionals needing an accessible introduction, or a friendly refresher, to the fundamentals of medical statistics.

Nursing and Healthcare Research at a Glance (Paperback): Alan Glasper, Colin Rees Nursing and Healthcare Research at a Glance (Paperback)
Alan Glasper, Colin Rees
R760 Discovery Miles 7 600 Ships in 10 - 15 working days

Nursing and Healthcare Research at a Glance is perfect for nursing and healthcare students, as well as newly qualified practitioners and anyone looking for a refresher or introduction to research. Covering a broad range of topics gathered under key sections, this essential book combines informative diagrams and images to provide memorable information for students on one page, and accessible, clearly written text on the facing page. It includes information on a range of quantitative and qualitative research methods, the process of gaining ethical permission, conducting research with special groups including children, and successfully conducting reviews of the literature. Key features include: * Clear and informative full colour illustrations throughout * An emphasis on need-to-know research information for busy students and healthcare staff * A wide range of research methods, currently used in modern healthcare research * An impressive line-up of specialist and well-known experts in the field of health and nursing research This book provides quick access to the principles and reality of research and its implementation within the education and practice environment. It is essential reading for anyone in health service education and service settings with limited time who need to draw on research evidence.

Implant Surfaces and their Biological and Clinical Impact (Hardcover, 2015 ed.): Ann Wennerberg, Tomas Albrektsson, Ryo Jimbo Implant Surfaces and their Biological and Clinical Impact (Hardcover, 2015 ed.)
Ann Wennerberg, Tomas Albrektsson, Ryo Jimbo
R3,203 R2,639 Discovery Miles 26 390 Save R564 (18%) Ships in 10 - 15 working days

This book provides the reader with the knowledge required in order to understand the chemical, physical, mechanical, and topographical aspects of implant surfaces, as well as their impact on the biological response. Common ways to modify implant surfaces are described, and methods for the evaluation of surface properties are presented in an easy-to-read style. Experimental results that have contributed to surface modifications relevant for commercial available implants are presented, with emphasis on in vivo and clinical studies. While the focus is primarily on surface modifications at the micrometer and nanometer levels, alterations at the millimeter level are also covered, including thread designs and their possible influence on stress distribution. In addition, it is analyzed how surface alterations have changed the clinical long-term results for certain groups of patients.

Safety of Health IT - Clinical Case Studies (Hardcover, 1st ed. 2016): Abha Agrawal Safety of Health IT - Clinical Case Studies (Hardcover, 1st ed. 2016)
Abha Agrawal
R3,061 R2,784 Discovery Miles 27 840 Save R277 (9%) Ships in 10 - 15 working days

This practical text provides an overview of the adverse consequences of health information technology (HIT) and its impact on patient safety. Specific cases of errors and risks related to various types of HIT are featured along with best practices for patient safety, workflows and organizational standards. The full impact of these challenges with meaningful solutions are openly examined. Written from a clinical perspective, healthcare professionals within multiple settings will find this timely book an invaluable resource to this essential and bourgeoning technology.

Superbugs - Deadly Microbes and the Extraordinary Race for a Cure: A Tale of Human Ingenuity (Paperback): Matt McCarthy Superbugs - Deadly Microbes and the Extraordinary Race for a Cure: A Tale of Human Ingenuity (Paperback)
Matt McCarthy
R405 R331 Discovery Miles 3 310 Save R74 (18%) Ships in 7 - 11 working days
Dermatopathology - Clinicopathological Correlations (Hardcover, 2014 ed.): Clay J. Cockerell, Martin C. Mihm, Brian J. Hall,... Dermatopathology - Clinicopathological Correlations (Hardcover, 2014 ed.)
Clay J. Cockerell, Martin C. Mihm, Brian J. Hall, Cary Chisholm, Chad Jessup, …
R4,921 R4,386 Discovery Miles 43 860 Save R535 (11%) Ships in 10 - 15 working days

Dermatopathology is a specialized branch of pathology in which there has been great progress as new techniques have become available to evaluate the pathology of the skin. Many of the advances in our knowledge and understanding of the skin and the diseases that affect it have been made by people with experience of both diagnostic pathology and clinical dermatology. With significant numbers of large textbooks available, there is a need to provide practical clinical information and concise criteria for pathologic diagnosis for pathologists and dermatologists looking for up-to-date diagnostic and management options.

Network Meta-Analysis for Decision-Making (Hardcover): Sofia Dias, A.E. Ades, Nicky J. Welton, Jeroen P. Jansen, Alexander J.... Network Meta-Analysis for Decision-Making (Hardcover)
Sofia Dias, A.E. Ades, Nicky J. Welton, Jeroen P. Jansen, Alexander J. Sutton
R1,566 R1,427 Discovery Miles 14 270 Save R139 (9%) Ships in 10 - 15 working days

A practical guide to network meta-analysis with examples and code In the evaluation of healthcare, rigorous methods of quantitative assessment are necessary to establish which interventions are effective and cost-effective. Often a single study will not provide the answers and it is desirable to synthesise evidence from multiple sources, usually randomised controlled trials. This book takes an approach to evidence synthesis that is specifically intended for decision making when there are two or more treatment alternatives being evaluated, and assumes that the purpose of every synthesis is to answer the question for this pre-identified population of patients, which treatment is best ? A comprehensive, coherent framework for network meta-analysis (mixed treatment comparisons) is adopted and estimated using Bayesian Markov Chain Monte Carlo methods implemented in the freely available software WinBUGS. Each chapter contains worked examples, exercises, solutions and code that may be adapted by readers to apply to their own analyses. This book can be used as an introduction to evidence synthesis and network meta-analysis, its key properties and policy implications. Examples and advanced methods are also presented for the more experienced reader. Methods used throughout this book can be applied consistently: model critique and checking for evidence consistency are emphasised. Methods are based on technical support documents produced for NICE Decision Support Unit, which support the NICE Methods of Technology Appraisal. Code presented is also the basis for the code used by the ISPOR Task Force on Indirect Comparisons. Includes extensive carefully worked examples, with thorough explanations of how to set out data for use in WinBUGS and how to interpret the output. N etwork Meta-Analysis for Decision Making will be of interest to decision makers, medical statisticians, health economists, and anyone involved in Health Technology Assessment including the pharmaceutical industry.

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