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SUITABLE FOR KINDLE AND OTHER EBOOK DEVICES Switch off the news and mute your tense WhatsApp chats - here are 101 family-friendly, fun, smart, silly, useful, good-to-know things to do and learn that will take your mind off what's going on outside the comfort of your own home, providing you with plenty of much needed moments of positivity and calm. Including (but not limited to!): * Quizzes * Anagrams * Poems * Riddles * Jokes * Word games * Fun facts * And other ways to occupy your time in a fulfilling way. Suitable for those aged 7 to 107, with the quizzes requiring some grown-up knowledge. And whilst you #StayHome, don't miss these other great titles from Sphere Books: ** The Bumper Book of Would You Rather? Over 350 hilarious hypothetical questions for ages 6 to 106 ** ** Home Sweet Home: The Little Book of Natural Cleaning ** ** Shelf Respect: A Book Lovers' Guide to Curating Book Shelves at Home **
This unique book contains not only a comprehensive up-to-date summary of the achievements made in all areas of Nematology in South Africa over more than half a century, but it also combines this rather technical part with an insiders narrative of how Nematology started and developed. It also demonstrates how the South African community of nematologists gradually adapted to major changes in agriculture. These were due to a major political shift followed by socio-economic changes and this in an often challenging natural environment. At the same time this book is conceived as a useful source for young scientists to provide them with practical knowledge and critical insight in the field of Nematology. The information given is based primarily on research conducted by nematologists in South Africa. Most of this research was aimed at finding workable solutions for nematological problems confronted by both large-scale commercial producers and smallholding farmers. During a period when funding for scientific research is becoming increasingly scarce, the future demand and quest for practical solutions by applied research will only increase.
This book provides up-to-date information on lymphatic filariasis supported with abundant images, tables and algorithms. It is a first such monograph on a disease that has varied presentations which are complete clinical entities, such as chyluria, hydrocele, elephantiasis, etc. This book consists of three parts, parasitology, acute clinical manifestations and chronic presentations of the disease. Approximately 120 million people are infected with lymphatic filariasis in tropical and subtropical countries. About a third of these suffer clinical consequences of this infection, and many are seriously disfigured. India, Indonesia and Nigeria are the most endemic countries in the world. In spite of Global Control Program of WHO, filariasis continues to be a significant medical challenge and current efforts underway will take a long time to bring it under control. Lymphatic Filariasis is meant for general surgeons, physicians, urologists and plastic surgeons, including the postgraduate students. Useful for epidemiologists, internists, and those involved in filariasis prevention programs.
Knowledge in the field of parasitology must be kept at a high level and up to date in order to fight a parasitosis as quickly and effectively as possible. This work, one of Springer's renowned and authoritative Major Reference Works, contributes to these goals in several ways. First, it comprises a number of entries, consisting of both in-depth essays and definitions. Secondly, the content has been improved even more by adding additional tables and high-quality figures. Thirdly, the extensive linking between definitions and essays facilitates information within a minimum of time. The Encyclopedia of Parasitology contains clearly structured essays in alphabetical order with extensive cross-references between definitions and related entries. International contributors, who are well-known specialists in their fields, give a comprehensive review of all parasites and therapeutic strategies in veterinarian and human parasitology. This 4th edition presents all important parasites of humans and animals in detail and the less important ones in short. Each parasite has its own large "chapter" with all subheadings (life cycle, morphology, treatment etc.). Topics common for other parasites and/or transmitted agents of diseases are presented in separate topics, which altogether are listed alphabetically. Furthermore all important parasitological and medical terms are explained as separate topics and are cross-linked to the chapters/topics, where they are explained intensively. Existing entries are updated and presented in the light of the latest knowledge.
The Oxford Handbook of Tropical Medicine, fourth edition is the definitive resource for medical problems in tropical regions, and in low-resource settings. Comprehensive in scope, and concise in style, this portable guide ensures that you always have the vital information you need at your fingertips. Fully revised and updated for its fourth edition, it includes brand new chapters on humanitarian crises, poisoning and envenoming, nosocomial infections, and antibiotic resistance. The paediatric illness sections have been expanded, and website links have been fully updated and extended. With the clear, easy-reference style of the trusted Oxford Handbook format, written and reviewed by an international team of clinical experts, this is a truly global handbook and an essential resource. Make sure you never leave home without it!
Contents: Host Defenses. Host Defenses against Fungal Pathogens. Epidemiology, Risk Factors, and Diagnostic and Management Considerations in Key At Risk Patient Populations. Solid Organ Transplant Recipients. Blood and Marrow Transplant Recipients.Oncology Patients. HIV Patients. Critical Care Patients. Pediatric Patients. Clinical Presentations of Invasive Fungal Infecgtions. Clinical Manifestations of Fungal Infections. Clinical Syndromes of Major Fungal Pathogens. Invasive CandidaInfections. Invasive Aspergillus Infections. Endemic Mycoses. Emerging Pathogens. Diagnostic Methodology. Cultural and Histologic Methods. Nonivasive Diagnostic serologic and PCR Methods. Radiological Procedures. Antifungal Agents. Polyenes.Azoles. Echinocandins. Other Classes of Antifungal Agents. Drug Interactions and Specific Toxicities. Adjunctive Treatment Approaches. Treatment Strategies. Prophylaxis. Empirical Therapy of Suspected Infections. Treatment of EstablishedInfections
This book primarily summarizes the imaging characteristics and theory of parasitic disease, offering a clinical guide and practical approach to understanding, preventing and diagnosing parasitic disease. Through imaging diagnosis and cross-research of imaging with autopsy and pathology, it highlights the chief characteristics and evolution of imaging, which provides primary scientific data for the understanding and research of parasitic disease. Divided into 9 chapters, this volume is fully illustrated with DR, CT and MRI images of different kinds of parasitic diseases, providing a valuable resource for radiologists in this field.
CONTAINS IMPORTANT INFORMATION ABOUT THE CORONAVIRUS! "Portrays epidemiologists as disease detectives who tirelessly hunt for clues and excel at deductive reasoning. Even Sherlock Holmes would be proud of this astute group of professionals."-Booklist This updated edition features a brand new section detailing important facts about the coronavirus and tips for keeping yourself and your family safe. Despite advances in health care, infectious microbes continue to be a formidable adversary to scientists and doctors. Vaccines and antibiotics, the mainstays of modern medicine, have not been able to conquer infectious microbes because of their amazing ability to adapt, evolve, and spread to new places. Terrorism aside, one of the greatest dangers from infectious disease we face today is from a massive outbreak of drug-resistant microbes. Deadly Outbreaks recounts the scientific adventures of a special group of intrepid individuals who investigate these outbreaks around the world and figure out how to stop them. Part homicide detective, part physician, these medical investigators must view the problem from every angle, exhausting every possible source of contamination. Any data gathered in the field must be stripped of human sorrows and carefully analyzed into hard statistics. Author Alexandra Levitt, PhD, is an expert on emerging diseases and other public health threats. Here she shares insider accounts she's collected that go behind the alarming headlines we've seen in the media: mysterious food poisonings, unexplained deaths at a children's hospital, a strange neurologic disease afflicting slaughterhouse workers, flocks of birds dropping dead out of the sky, and drug-resistant malaria running rampant in a refugee camp. Meet the resourceful investigators-doctors, veterinarians, and research scientists-and discover the truth behind these cases and more.
With parasitic diseases increasing worldwide it 's vitally important that radiologists in particular stay up to date with developments. In this brilliantly useful volume, the authors cover the imaging findings for parasitic diseases that can affect the human body using modern imaging equipments. Every chapter consists of a short description of causative agent, epidemiology, clinical manifestations, laboratory tests, and imaging findings with illustrative examples of parasitic diseases.
Diagnosis of parasitic lung diseases is often difficult as their clinical manifestations can mimic common respiratory illnesses and routine tests can fail to detect the infections. "Parasitic Diseases of the Lungs" is designed as a practical guide for pathologists who encounter parasitic diseases of the lung in their daily routine. The book comprises eight chapters. After discussion of the handling of lung biopsies from patients with suspected parasitic disease, individual chapters focus on Protozoa, Nematoda, Trematoda, and Cestoda. The morphologic patterns associated with various parasitic infections are then analyzed, and differentiation between artifacts and parasites is discussed. The final chapter is devoted to the immunocompromised patient and covers general principles of histologic evaluation, parasites associated with HIV and AIDS, and the features of diffuse alveolar damage.
This is a comprehensive work summarizing the current state of knowledge of the biology of the hard ticks (Acari: Ixodidae) of Southern Africa (South Africa, Namibia, Botswana, Swaziland, Lesotho and Maputo Province, Mozambique). It provides an overview of the history of tick research in Southern Africa and the evolution of our knowledge of the ticks' distribution and biology, as well as the methods used to determine tick distribution, abundance and host preference. The morphologies of most of the tick species known to occur in Southern Africa are described and illustrated, and their distributions are described and mapped in relation to the biomes of the region. The known hosts for each tick species are listed, and the tick's host preferences are discussed. Information on most species life cycle in the laboratory and the field, and their seasonal occurrence, is summarized. The diseases of animals and humans transmitted or caused by each tick species are summarized in relation to tick ecology. Aspects of the biology of the major hosts relevant to tick infestations are described, and extensive tick/host and host/tick lists are provided for each country
This book offers a state-of-the-art report on recent discoveries concerning viral, bacterial, and parasite infectious cancers. Cancer is one of the most common causes of death and diseases in human populations, and 15%-25% of human cancers in worldwide are considered to result from chronic infection by pathogens. Most oncology textbooks address genetic mutation, but not infectious agents such as viruses, bacteria and parasites. As such this book stimulates further research in the new area between cancers and chronic infection, and discusses the epidemiology and molecular biology of infectious causes of cancers. It also explores the prevention and treatment of infection-related cancers, and brings pathogenic research to the forefront in the never-ending endeavor to understand how pathogens maneuver and negotiate in a complex environment, including the micro/macro- environment of the human host. Further, it highlights the urgent need for a concerted program to develop vaccines and other diagnosis and interventions that will eventually help prevent and treat infectious cancers, and decrease their burden on human populations. It offers graduate students and researchers a comprehensive overview of the infectious causes of cancers.
This book provides up-to-date information on the characteristics of each species of intestinal fluke found in humans and on the management of infections caused by these trematodes. Biology, epidemiology, host-parasite relationships, pathogenicity, clinical aspects, diagnosis, and treatment are all reviewed in detail. The zoonotic intestinal flukes comprise 38 genera belonging to 16 families. They are morphologically diverse and each species has a characteristic life cycle and geographical distribution. Intestinal fluke infections are commonly considered as tropical endemic diseases in Asian countries, where 6 million people are infected, but the geographical limits and populations at risk are expanding and changing owing to a range of factors, including growing international markets, improved transportation systems, changes in eating habits, demographic trends, and climate change. While the pathogenicity of intestinal flukes is generally mild, the impact in immunocompromised individuals requires clarification and some diagnostic problems remain to be solved. In exploring all aspects of human intestinal fluke infections, this book will be invaluable for clinicians and researchers alike.
This textbook focuses on the most important parasites affecting dogs, cats, ruminants, horses, pigs, rabbits, rodents, birds, fishes, reptiles and bees. For each parasite, the book offers a concise summary including its distribution, epidemiology, lifecycle, morphology, clinical manifestations, diagnosis, prophylaxis and therapeutic measures. Numerous informative tables and more than 500 color micrographs and schemes present the most important aspects of the parasites, their induced diseases and the latest information on suitable prevention and control measures. 100 questions at the end of the book offer readers the chance to test their comprehension. The book is well suited as both a textbook and a reference guide for veterinarians, students of the veterinary and life sciences, veterinarian nurses, laboratory staff, and pet and livestock owners.
This book covers all aspects of Neglected Tropical Diseases in the region of South Asia. NTDs constitute a significant part of the total disease burden in this geographic area, including soil borne helminth infections, vector borne viral infections, protozoan infections and a few bacterial infections. The current volume covers the most common neglected viral, bacterial and protozoan infections. On top of that, the last part of the volume is dedicated to the management of neglected tropical diseases.
This textbook provides an up-to-date overview of the most important parasites in humans and their potential vectors. For each parasite, the book offers a concise summary including its distribution, epidemiology, life cycle, morphology, clinical manifestations, diagnosis, prophylaxis and therapeutic measures. Numerous tables, diagrams and over 200 colorful illustrations highlight the main aspects of parasitic infestations and present suitable control measures. 60 questions help to test readers' theoretical knowledge of the field. In short, the book is highly recommended for anyone looking to delve into the field of human parasitology. It is intended for students of biology and human medicine, medical doctors, pharmacists and laboratory staff alike. Furthermore, persons who plan to visit or live longer in endemic regions will find essential information on necessary preventive and control measurements.
The type 2 immune response that develops during infectious disease has undergone major paradigm shifts in the last several years as new cell types and pathways have been identified. It is now clear that the type 2 immune response, characterized by elevations in specific cytokines, including IL-4, IL-5 and IL-13, is associated with helminth infections in both humans and mice. This response is complex and includes effector functions that mediate resistance, contributing to expulsion and in some cases destruction, of the parasite. But just as importantly, the type 2 immune response can also mediate tolerance mechanisms, which can mitigate tissue injury as these large multicellular parasites transit through vital organs. The tolerance mechanisms include both tissue repair and immune regulatory effects. These latter aspects of the helminth-induced type 2 immune response are increasingly recognized as a potential resource that can be mined for the development of novel immunotherapies that may enhance wound healing, control of autoimmune and inflammatory diseases and regulation of metabolic homeostasis. In this book, leading researchers in this exciting and dynamic field discuss the latest findings and emerging concepts, providing an intellectual framework that can be used as a basis for new discoveries and potentially new treatments for diseases associated with inflammation.
This new volume provides exhaustive knowledge on a wide range of natural products and holistic concepts that have provided promising in the treatment of leishmaniasis. Including the major natural therapies as well as traditional formulations, over 300 medicinal plants and 150 isolated compounds that are reported to have beneficial results in the treatment of the disease are explored in this comprehensive work. This book also acts as an important resource on various anti-inflammatory plants used to treat various inflammatory conditions of the disease.
Dickson D. Despommier's vivid, visceral account of the biology, behavior, and history of parasites follows the interplay between these fascinating life forms and human society over thousands of years. Despommier focuses on long-term host-parasite associations, which have evolved to avoid or even subvert the human immune system. Some parasites do great damage to their hosts, while others have signed a kind of "peace treaty" in exchange for their long lives within them. Many parasites also practice clever survival strategies that medical scientists hope to mimic as they search for treatments for Crohn's disease, food allergies, type 1 diabetes, organ transplantation, and other medical challenges. Despommier concentrates on particularly remarkable and often highly pathogenic organisms, describing their lifecycles and the mechanisms they use to avoid elimination. He details their attack and survival plans and the nature of the illnesses they cause in general terms, enabling readers of all backgrounds to steal a glimpse into the secret work of such effective invaders. He also points to the cultural contexts in which these parasites thrive and reviews the current treatments available to defeat them. Encouraging scientists to continue to study these organisms even if their threat is largely contained, Despommier shows how closer dissection of the substances parasites produce to alter our response to them could help unravel some of our most complex medical conundrums.
Aspergillosis is an infection or allergic response caused by the fungus Aspergillus. Aspergillus conidia are widely dispersed in the environment and can easily reach human lungs and/or paranasal sinuses: most people inhale Aspergillosis spores every day
The label Aspergillosis is used for several diverse clinical conditions. For instance, invasive Aspergillosis typically affects severely immunocompromised patients such as those with prolonged neutropenia or receiving therapy with steroids. On the other hand, allergic forms of Aspergillosis cause exuberant clinical syndromes that mostly affect patients with asthma and cystic fibrosis. Slowly destructive lung diseases may also occur in the apparently immunocompentent host, especially in the context of previous damage to the lung architecture. These are difficult-to-diagnose infections, and diagnostic tests perform differently depending on the specific scenario.
This book summarizes the current knowledge about Aspergillosis, covering:
Written by internationally respected authors, the information presented in this book adds for a better understanding of Aspergillosis by providing a comprehensive and clear overview of all aspects associated with this complex disease.
Toxocara is a parasitic helminth worm which continues to stimulate both public concern and scientific interest. "Toxocara canis" and "T.cati," the most studied species, are gastrointestinal parasites of dogs and cats and their eggs can contaminate the environment, thus exposing humans and other mammals and birds to infection. Many questions remain unanswered about the host-parasite relationship, its epidemiology and public health significance. Veterinarians and clinicians are interested in its importance as a zoonosis. The parasite's capacity to cause ocular disease is of concern to ophthalmologists, while its propensity to stimulate allergic manifestations is of interest to allergologists, dermatologists and respiratory medicine specialists. Furthermore "Toxocara" provides a unique model system to explore questions in parasite biology. This book provides a comprehensive review of Toxocara and the disease it causes known as toxocariasis.
The book, in its Second Edition, has been thoroughly revised considering the feedback received from the readers. The text has been simplified. New information has been added, and at the same time, extra details have been deleted to make the book concise. The new edition introduces a chapter on Medically Important Snails (Chapter 9).We, the human are the host of many parasites, which cause major public health problems, untold suffering and death. Thus, three major groups of parasites-protozoa (flagellates, amoebas, and malarial parasites), helminthes (flukes, tapeworms, and roundworms), and arthropods (insects and arachnids) have been discussed with suitable illustrations. Morphology, lifecycle, mode of transmission, incidence, symptoms, diagnosis, and prevention of medically important parasites have been discussed in light of recent researches. In addition, the chapters, namely, the Evolutionary Aspects of Hosts and Parasites and Present Trends of Parasitic Importance add further value to the book.The book has been written for the undergraduate and postgraduate students of Zoology and other Life Sciences disciplines. In addition, the medical students, public health workers and health professionals also find this text useful.Key Features:Diagrammatical presentation of life cycle of parasites.Suitably illustrated text.Discusses the food-borne, water-borne and vector-borne parasitic diseases.Contains glossary of important terms.
Chagas disease is a potentially life threatening condition that was historically mainly endemic to Latin America. Over the last decade, however, the disease has spread to and is increasingly prevalent in other continents such as North America and Europe, with an estimated 7 million people infected worldwide. It is primarily transmitted by insect vectors that carry the parasite Trypanosoma cruzi, the disease agent. In areas where there is vector control and in non-endemic countries, it is mainly transmitted via congenital infection. Cardiac and gastrointestinal complications are common in untreated individuals. This book offers a comprehensive overview of Chagas disease, including its vectorial and congenital transmission, and molecular diagnosis, which is essential for screening, and developing and providing timely, effective anti-trypanosomal treatment. Written by experts working with infected patients on a daily basis, it discusses the pathogenesis of congenital, cardiac, gastrointestinal and oral Chagas disease, as well as its treatment and the pharmacological aspects of drug development in this area. Chapter "Chagas Disease Treatment Efficacy Biomarkers: Myths and Realities" is available open access under a via link.springer.com.
For human health, leishmaniasis is among the most important protozoan diseases, superseded only by malaria. Globally, 10 to 12 million people are infected with 1.5 million new cases every year. The development of cheaper new drugs is urgently needed for this neglected disease that is developing resistance to current treatments. Chemotherapy remains the only treatment option for the bulk of patients. However, this is largely unaffordable for most. In the past three years numerous advances in drug discovery have been made for treating this disease by exploiting diverging metabolic pathways between the Leishmania enzymes and their hosts, using nanotechnology to target the immune cell phagolysosomes where Leishmania resides. Drug Discovery for Leishmaniasis aims to provide a perspective of the current treatments and their challenges, blended with the emerging strategies and methodologies that will drive new target appraisals and drug developments, as well as addressing the molecular basis of resistance in Leishmania. Recent studies have shown that leishmaniasis affects some of the poorest people in the world, with 95% of fatal cases occurring in only 6 countries. With the WHO goal of eliminating this public health problem in the South-east Asia Region by 2020, this book will be important for anyone who is interested in neglected tropical diseases.
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