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Now in its 5th edition, Wolters Kluwer's AJN Award Winning text,Theoretical Basis for Nursing , provides an overview of nursing theory that includes the essential information that a student needs to understand theory and its application to practice. Students-with little to no knowledge of nursing theory-will gain insight into how theory can affect their practice and make them better nurses. In Unit I, Students are ushered through the skills needed to develop, analyze, and evaluate theory for use in their careers. This skill set will help students pursuing all potential career paths-in nursing practice, research, administration, management, and/or education. As a unique focus in Unit II, grand theories are discussed in relation to 1) human needs, 2) interactive process, and 3) unitary process. This unit provides the perfect amount of information-just enough for the reader to 1) understand the basis of the work and 2) become enticed enough in the material to want to select one or two theories for primary source study. Also, because of an emphasis on middle range theory in nursing programs, the authors present an overview of selected middle range theories, examining their origins and growth. The broad range of middle range theories sampled will point students in the right direction to search for others appropriate to their practice. Some NEW! theories to this edition include aerohemodynamic theory, transtheoretical model of change, and the precede/proceed model. In Unit II, there will be an enhanced discussion of Evidence-based practice (EBP) and nursing theory. As its next frontier, nursing theory will increasingly focus on EBP protocols, and McEwen & Wills help students understand the inter-relatedness of theory, research, and practice. This edition includes an enhanced discussion of the history of EBP and practice-based evidence (PBE). In Unit III, students explore "shared theories," benefitting from the body of knowledge that can be distilled from other disciplines. This unit is unique to this text, and students will discover stories of how nurses have used shared theories in their own practice. In this edition, a NEW! chapter called "Ethical Theories and Principles" will be included in this unit. The text concludes with Unit IV, a summary of how theories should be and are applied in nursing. Functioning as a practical guide, separate chapters cover nursing practice, nursing research, nursing administration and management, and nursing education. The evolving development of practice theories and importance of evidence-based practice guidelines are critical to theory application in nursing today. NEW! In our application to practice chapter (Chapter 19), we will add examples of the theoretical underpinnings related to the clinical practice guidelines. Reinforcing its emphasis on practice, both the book and its resources on thePoint will include case studies with examples from nursing in general through advanced practice scenarios. Because Nursing Theory is often a reading and writing intensive course, this text comes with a Scholarly Writing in Nursing: Best Practices. This resource covers the basics of APA as well as good writing principles, and it also provides weblinks to additional resources. This edition will also feature improved indices making content in the text easier to find quickly. This text is accompanied by a robust instructor resource package featuring an Instructor's Guide, Case Studies with supportive curriculum, PowerPoints, and more. Theoretical Basis for Nursing, 5th Edition offers an inspiring message to readers to contribute to the ongoing development, application, analysis, and evaluation of concepts, principles, theories, and models to advance the discipline of nursing. According to authors McEwen & Wills, "As the health profession with the largest number of providers, nursing has the greatest potential to have the greatest impact on health and healthcare delivery."
The bite of the tsetse fly - a burning sting into the skin - causes a descent into violent fever and aching pains. Severe bouts of insomnia are followed by mental deterioration, disruption of the nervous system, coma and ultimately death. Sleeping sickness, also known as Human African trypanosomiasis, is one of Africa's major killers. It puts 60 million people at risk of infection, occurs in 36 countries in sub-Saharan Africa, and claims the lives of many thousands of people every year. Transmitted by the tsetse fly, trypanosomiasis affects both humans and cattle. The animal form of the disease severely limits livestock production and farming, and in people the toxic effects of the treatment for the brain disease can be as painful and dangerous as the disease itself. Existing in the shadow of malaria and AIDS, it is an overlooked disease, ignored by pharmaceutical companies and largely neglected by the western world. Peter Kennedy has devoted much of his working life to researching sleeping sickness in Africa, and his autobiographical account shares not only his trials and experiences, evoking our empathy with the affected patients, but an explanation of the disease, including its history and its future. Interwoven with African geography, his compassionate story reveals what it is like to be a young doctor falling in love with Africa, and tells of his building of a vocation in the search for a cure for this cruel disease.
In this publication, description of the basic histology tissues is followed by a description of the histology of the different organs and systems in the human. The subject contents is presented on a relevant clinical level, and students in both medicine and dentistry, as well as related health professions, such as nursing, occupational therapy and physiotherapy, will find it simple and meaningful. The terminology used in the publication correlates with the writing style used as standard in English medical, dental and health care science' schools.
'Bad Science' hilariously exposed the tricks that quacks and journalists use to distort science, becoming a 400,000 copy bestseller. Now Ben Goldacre puts the $600bn global pharmaceutical industry under the microscope. What he reveals is a fascinating, terrifying mess. Doctors and patients need good scientific evidence to make informed decisions. But instead, companies run bad trials on their own drugs, which distort and exaggerate the benefits by design. When these trials produce unflattering results, the data is simply buried. All of this is perfectly legal. In fact, even government regulators withhold vitally important data from the people who need it most. Doctors and patient groups have stood by too, and failed to protect us. Instead, they take money and favours, in a world so fractured that medics and nurses are now educated by the drugs industry. The result: patients are harmed in huge numbers. Ben Goldacre is Britain's finest writer on the science behind medicine, and 'Bad Pharma' is the book that finally prompted Parliament to ask why all trial results aren't made publicly available - this edition has been updated with the latest news from the select committee hearings. Let the witty and indefatigable Goldacre show you how medicine went wrong, and what you can do to mend it.
Required reading in many medical and healthcare institutions, How to Read a Paper is a clear and wide-ranging introduction to evidence-based medicine and healthcare, helping readers to understand its central principles, critically evaluate published data, and implement the results in practical settings. Author Trisha Greenhalgh guides readers through each fundamental step of inquiry, from searching the literature to assessing methodological quality and appraising statistics. How to Read a Paper addresses the common criticisms of evidence-based healthcare, dispelling many of its myths and misconceptions, while providing a pragmatic framework for testing the validity of healthcare literature. Now in its sixth edition, this informative text includes new and expanded discussions of study bias, political interference in published reports, medical statistics, big data and more. Offers user-friendly guidance on evidence-based healthcare that is applicable to both experienced and novice readers Authored by an internationally recognised practitioner and researcher in evidence-based healthcare and primary care Includes updated references, additional figures, improved checklists and more How to Read a Paper is an ideal resource for healthcare students, practitioners and anyone seeking an accessible introduction to evidence-based healthcare.
The authoritative guide for Data Monitoring Committees--fully revised and updated The number of clinical trials sponsored by government agencies and pharmaceutical companies has grown in recent years, prompting an increased need for interim monitoring of data on safety and efficacy. Data Monitoring Committees (DMCs) are an essential component of many clinical trials, safeguarding trial participants and protecting the credibility and validity of the study. Data Monitoring Committees in Clinical Trials: A Practical Perspective, 2nd Edition offers practical advice for those managing and conducting clinical trials and serving on Data Monitoring Committees, providing a practical overview of the establishment, purpose, and responsibilities of these committees. Examination of topics such as the composition and independence of DMCs, statistical, philosophical and ethical considerations, and determining when a DMC is needed, presents readers with a comprehensive foundational knowledge of clinical trial oversight. Providing recent examples to illustrate DMC principles, this fully-updated guide reflects current developments and practices in clinical trial oversight and offers expanded coverage of emerging issues and challenges in the field. This new second edition covers the most current information on DMC policies, issues in monitoring trials using new designs, and recent trial publications relevant to DMC decision-making. - Presents practical advice for those managing and conducting clinical trials and serving on Data Monitoring Committees - Illustrates the types of challenging issues Data Monitoring Committees face in practical situations - Provides updated and expanded coverage of topics including regulatory and funding agency guidelines and trial designs and their associated demands and limitations - Includes a new chapter addressing legal issues that affect DMC members and discusses general litigation concerns relevant to clinical research - Expands treatment of current journal publications addressing DMC issues Data Monitoring Committees in Clinical Trials: A Practical Perspective, 2nd Edition is a must-have text for anyone engaged in DMC activities as well as trial sponsors, clinical trial researchers, regulatory and bioethics professionals, and those associated with clinical trials in academic, government and industry settings.
To download an e-inspection copy click here or for more information contact your local sales representative. What is research and how does it work in the context of nursing, health and social care? Now in its 6th edition, this easy to read guide keeps on providing a concise overview of the different research methods and terminology and helps readers understand how research is implemented in practice. The new edition includes: Case examples of real research from a variety of settings and countries Updates in light of the new NMC standards, more on critical appraisal tools and service improvement Chapter learning outcomes and key points Free online resources including an interactive glossary, reflective exercises and free access to SAGE journal articles for students, as well as SAGE videos and seminar notes for lecturers and more. This is essential reading for undergraduate and postgraduate students of nursing and health in the UK and internationally.
Nursing and Healthcare Research at a Glance is perfect for nursing and healthcare students, as well as newly qualified practitioners and anyone looking for a refresher or introduction to research. Covering a broad range of topics gathered under key sections, this essential book combines informative diagrams and images to provide memorable information for students on one page, and accessible, clearly written text on the facing page. It includes information on a range of quantitative and qualitative research methods, the process of gaining ethical permission, conducting research with special groups including children, and successfully conducting reviews of the literature. Key features include: * Clear and informative full colour illustrations throughout * An emphasis on need-to-know research information for busy students and healthcare staff * A wide range of research methods, currently used in modern healthcare research * An impressive line-up of specialist and well-known experts in the field of health and nursing research This book provides quick access to the principles and reality of research and its implementation within the education and practice environment. It is essential reading for anyone in health service education and service settings with limited time who need to draw on research evidence.
Correctly understanding and using medical statistics is a key skill for all medical students and health professionals. In an informal and friendly style, Medical Statistics from Scratch provides a practical foundation for everyone whose first interest is probably not medical statistics. Keeping the level of mathematics to a minimum, it clearly illustrates statistical concepts and practice with numerous real-world examples and cases drawn from current medical literature. Medical Statistics from Scratch is an ideal learning partner for all medical students and health professionals needing an accessible introduction, or a friendly refresher, to the fundamentals of medical statistics.
A clinical psychiatrist explores the effects of DMT, one of the most powerful psychedelics known.
- A behind-the-scenes look at the cutting edge of psychedelic research.
- Provides a unique scientific explanation for the phenomenon of alien abduction experiences.
From 1990 to 1995 Dr. Rick Strassman conducted U.S. Government-approved and funded clinical research at the University of New Mexico in which he injected sixty volunteers with DMT, one of the most powerful psychedelics known. His detailed account of those sessions is an extraordinarily riveting inquiry into the nature of the human mind and the therapeutic potential of psychedelics. DMT, a plant-derived chemical found in the psychedelic Amazon brew, ayahuasca, is also manufactured by the human brain. In Strassman's volunteers, it consistently produced near-death and mystical experiences. Many reported convincing encounters with intelligent nonhuman presences, aliens, angels, and spirits. Nearly all felt that the sessions were among the most profound experiences of their lives.
Strassman's research connects DMT with the pineal gland, considered by Hindus to be the site of the seventh chakra and by Rene Descartes to be the seat of the soul. DMT: The Spirit Molecule makes the bold case that DMT, naturally released by the pineal gland, facilitates the soul's movement in and out of the body and is an integral part of the birth and death experiences, as well as the highest states of meditation and even sexual transcendence. Strassman also believes that "alien abduction experiences" are brought on by accidental releases of DMT. If used wisely, DMT could trigger a period of remarkable progress in the scientificexploration of the most mystical regions of the human mind and soul.
A practical guide to network meta-analysis with examples and code In the evaluation of healthcare, rigorous methods of quantitative assessment are necessary to establish which interventions are effective and cost-effective. Often a single study will not provide the answers and it is desirable to synthesise evidence from multiple sources, usually randomised controlled trials. This book takes an approach to evidence synthesis that is specifically intended for decision making when there are two or more treatment alternatives being evaluated, and assumes that the purpose of every synthesis is to answer the question for this pre-identified population of patients, which treatment is best ? A comprehensive, coherent framework for network meta-analysis (mixed treatment comparisons) is adopted and estimated using Bayesian Markov Chain Monte Carlo methods implemented in the freely available software WinBUGS. Each chapter contains worked examples, exercises, solutions and code that may be adapted by readers to apply to their own analyses. This book can be used as an introduction to evidence synthesis and network meta-analysis, its key properties and policy implications. Examples and advanced methods are also presented for the more experienced reader. Methods used throughout this book can be applied consistently: model critique and checking for evidence consistency are emphasised. Methods are based on technical support documents produced for NICE Decision Support Unit, which support the NICE Methods of Technology Appraisal. Code presented is also the basis for the code used by the ISPOR Task Force on Indirect Comparisons. Includes extensive carefully worked examples, with thorough explanations of how to set out data for use in WinBUGS and how to interpret the output. N etwork Meta-Analysis for Decision Making will be of interest to decision makers, medical statisticians, health economists, and anyone involved in Health Technology Assessment including the pharmaceutical industry.
Includes a revised taxonomic outline for the phyla Bacteroidetes, Planctomycetes, Chlamydiae, Spirochetes, Fibrobacters, Fusobacteria, Acidobacteria, Verrucomicrobia, Dictyoglomi, and Gemmatomonadetes based upon the SILVA project as well as a description of more than 153 genera in 29 families. Includes many medically important taxa.
Although anterior cruciate ligament (ACL) reconstruction has a high success rate, a substantial number of patients are left with unsatisfactory results. "Revision ACL Reconstruction: Indications and Technique" provides detailed strategies for planning and executing revision ACL reconstructions. Concise chapters by a leading group of international orthopedic surgeons cover the diagnosis of failed ACL reconstruction, patient evaluation, preoperative planning for revision ACL surgery and complex technical considerations.
When data from all aspects of our lives can be relevant to our health - from our habits at the grocery store and our Google searches to our FitBit data and our medical records - can we really differentiate between big data and health big data? Will health big data be used for good, such as to improve drug safety, or ill, as in insurance discrimination? Will it disrupt health care (and the health care system) as we know it? Will it be possible to protect our health privacy? What barriers will there be to collecting and utilizing health big data? What role should law play, and what ethical concerns may arise? This timely, groundbreaking volume explores these questions and more from a variety of perspectives, examining how law promotes or discourages the use of big data in the health care sphere, and also what we can learn from other sectors.
#10 on Amazon Charts, USA Today Bestseller "This book is my best attempt to tell the truth about my research, the culture in science today which is hostile to new ideas, and what science can really do if allowed to pursue promising areas of inquiries."-Dr. Judy Mikovits, PhD This is a story for anybody interested in the peril and promise of science at the very highest levels in our country. On July 22, 2009, a special meeting was held with twenty-four leading scientists at the National Institutes of Health to discuss early findings that a newly discovered retrovirus was linked to chronic fatigue syndrome (CFS), prostate cancer, lymphoma, and eventually neurodevelopmental disorders in children. When Dr. Judy Mikovits finished her presentation, the room was silent for a moment, then one of the scientists said, "Oh my God!" The resulting investigation would be like no other in science. For Dr. Mikovits, a twenty-year veteran of the National Cancer Institute, this was the midpoint of a five-year journey that would start with the founding of the Whittemore-Peterson Institute for Neuro-Immune Disease at the University of Nevada, Reno, and end with her as a witness for the federal government against her former employer, Harvey Whittemore, for illegal campaign contributions to Senate Majority Leader Harry Reid. On this journey Dr. Mikovits would face the scientific prejudices against CFS, wander into the minefield that is autism, and through it all struggle to maintain her faith in God and the profession to which she had dedicated her life.
Crash Course - your effective every-day study companion PLUS the perfect antidote for exam stress! Save time and be assured you have the essential information you need in one place to excel on your course and achieve exam success. A winning formula now for over 20 years, each series volume has been fine-tuned and fully updated - with an improved full-colour layout tailored to make your life easier. Especially written by senior students or junior doctors - those who understand what is essential for exam success - with all information thoroughly checked and quality assured by expert Faculty Advisers, the result are books which exactly meet your needs and you know you can trust. This volume concisely brings together the wide range of skills needed for interpreting or conducting medical research and audit. It starts with the basics of medical data analysis and interpretation, followed by how to critically review published studies and even extends to advice on career advancement including CV writing, securing academic opportunities and teaching. This book will allow you to build competence and confidence in the world of medical research. ? Provides the exam syllabus in one place - saves valuable revision time Written by senior students and recent graduates - those closest to what is essential for exam success Quality assured by leading Faculty Advisors - ensures complete accuracy of information Features the ever popular 'Hints and Tips' boxes and other useful aide-memoires - distilled wisdom from those in the know Updated self-assessment section matching the latest exam formats - confirm your understanding and improve exam technique fast
Thalidomide: patented in Germany as a non-toxic cure-all for sleeplessness and morning sickness. A wonder drug with no side effects. We know differently now. Today, thalidomide is a byword for tragedy and drug reform - a sign of what happens when things aren't done `the right way'. But when it was released in the 1950s, it was the best thing since penicillin - something that doctors were encouraged to prescribe to all of their patients. Nobody could anticipate what it actually did: induce sleeping, prevent morning sickness, and drastically harm unborn children. But, whilst thalidomide rampaged and ravaged throughout most of the West, it never reached the United States. It landed on the desk of Dr Frances Kelsey, and there it stayed as she battled bureaucracy, patriarchy, and the Establishment in an effort to prove that it was dangerous. Frankie is her story.
This book is a continuation of the book Medicine Researcher Biographical Sketches and Research Summaries which compiles research summaries from a number of different focuses in this important field.
FUNDAMENTALS OF BIOSTATISTICS leads you through the methods, techniques, and computations of statistics necessary for success in the medical field. Every new concept is developed systematically through completely worked out examples from current medical research problems.
The focus of this book is to introduce up-to-date information on applications and practical use of RNA for agriculture, biotechnology and medicine. It provides unique ideas, tools, and methods in detail from a variety of scientific and technical disciplines. RNA science has progressed enormously in recent decades, and vast amounts of information on RNA functions and their regulatory mechanisms are becoming available. Such a progress opened the door to an age of practical application of RNA in many fields including agriculture, plant science, medical science, brewing and fermentation technology, and material production. This book inspires its readership and contributes to not only expansion in application of RNA but also to basic research.
The 'miracle drug' penicillin was first given intravenously to a patient in Oxford on 12 February 1941, leading to a transformation in the way that bacterial infection is understood and treated. What was to become one of the greatest stories in biomedical history not only had roots in Oxford, but was the latest in a line of pivotal medical discoveries made in the city. This short illustrated history chronicles the story of Oxford's contribution to science, from its medieval origins to its present status as one of the world's leading scientific institutions. In charting Oxford's remarkable history, the book showcases twenty discoveries which have shaped medical science across the centuries, with worldwide impact. In the early seventeenth century few centres could rival Oxford in the field of experimental medicine. William Harvey, Thomas Willis and Thomas Sydenham all gained eponymous immortality with their pioneering research into the circulation of the blood and the workings of the human body. In the early twentieth century Dorothy Hodgkin's development of x-ray crystallography earned her a Nobel Prize and more recently, Richard Doll's work on smoking, pioneering glucose sensors for diabetes and new treatments for haemophilia have helped save millions of lives. Great Medical Discoveries traces how these examples of groundbreaking and vital work form part of a wider tapestry of medical research, from the discovery of anaesthetics to pioneering neurosurgery, and demonstrates how such enduring contributions to medical science have helped to shape our lives, both locally and internationally.
Diabetes is a complex disease and is also one of the most common. It is very difficult to reach an accurate estimate for the global prevalence of diabetes since the standards and methods of data collection vary widely in different parts of the world. In addition, many potential sufferers are not included in the count because according to an estimate about 50% of cases remain undiagnosed for up to 10 years. However, according to an estimate for 2010, globally, there are about 285 million people (amounting to 6.4% of the adult population) suffering from this disease. This number is estimated to increase to 439 million by 2030 if no cure is found. The general increase in life expectancy, leading to an ageing population, and the global rise in obesity are two main reasons for the increase.With the basic platform set, Editor presents his views and advice to the readers, especially to diabetic patients suffering from T2DM, on the basis of his observations and information collected from other diabetics.
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