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Books > Science & Mathematics > Biology, life sciences > Biochemistry > Proteins

Proteomics in Practice - A Guide to Successful Experimental Design (Hardcover, 2nd, Completely Revised Edition): Reiner... Proteomics in Practice - A Guide to Successful Experimental Design (Hardcover, 2nd, Completely Revised Edition)
Reiner Westermeier, Tom Naven, Hans Rudolf Hopker
R2,670 R1,883 Discovery Miles 18 830 Save R787 (29%) Shipped within 7 - 13 working days

A thoroughly revised edition of the successful practical guide to experimental methods in proteomics, which now includes DIGE technology and liquid chromatography.
The first part, written in a textbook style, presents the various techniques and routes required in approaching proteomic analysis. Key methods explained are electrophoretic techniques including isoelectric focusing, SDS page, 2-D page and DIGE, and liquid chromatography techniques including ion exchange, affinity chromatography and reversed-phase HPLC. Mass-spectrometric techniques such as MALDI, ESR and FT ICR are addressed as well as a section on proteome functionality. The second part is a comprehensive, laboratory manual spanning the full range of methods from sample preparation to protein identification. The third part is a unique troubleshooting guide, designed to answer many of the frequently asked questions regarding proteome analysis. The final section contains a thorough reference list to guide interested readers towards further information.
Updates of protocols as well as animations illustrating crucial methodological steps are available on the Web at http: //www.wiley-vch.de/books/info/978-3-527-31941-1/index.html

Protein Phosphorylation in Parasites - Novel Targets for Antiparasitic Intervention (Hardcover): Christian Doerig, Gerald... Protein Phosphorylation in Parasites - Novel Targets for Antiparasitic Intervention (Hardcover)
Christian Doerig, Gerald Spaeth, Martin Wiese; Series edited by Paul M. Selzer
R3,517 R2,468 Discovery Miles 24 680 Save R1,049 (30%) Shipped within 7 - 13 working days

This is the first book to collect and summarize in one publication the efforts to use kinases or phosphatases for drug development against parasite infections.
The editors and contributors comprise the Who is Who in the field, and they are comprehensive in covering every aspect of the topic, from basic research findings to translational approaches in drug development
The result will be welcomed by everyone in academia and industry participating in the global effort to finally combat the major diseases caused by eukaryotic parasites. This is volume one of a two-volume treatise, the second being exclusively dedicated to efforts to combat malaria using the same approach.

Amyloid Fibrils and Prefibrillar Aggregates - Molecular and Biological Properties (Hardcover): Daniel Erik Otzen Amyloid Fibrils and Prefibrillar Aggregates - Molecular and Biological Properties (Hardcover)
Daniel Erik Otzen
R3,860 R2,705 Discovery Miles 27 050 Save R1,155 (30%) Shipped within 7 - 13 working days

Summing up almost a decade of biomedical research, this topical and eagerly awaited handbook is the first reference on the topic to incorporate recent breakthroughs in amyloid research.
The first part covers the structural biology of amyloid fibrils and pre-fibrillar assemblies, including a description of current models for amyloid formation. The second part looks at the diagnosis and biomedical study of amyloid in humans and in animal models, while the final section discusses pharmacological approaches to manipulating amyloid and also looks at its physiological roles in lower and higher organisms. For Biochemists, Molecular Biologists, Neurobiologists, Neurophysiologists and those working in the Pharmaceutical Industry.

Antimicrobial Peptides (Hardcover): David A. Phoenix, Sarah R. Dennison, Frederick Harris Antimicrobial Peptides (Hardcover)
David A. Phoenix, Sarah R. Dennison, Frederick Harris
R2,990 R2,098 Discovery Miles 20 980 Save R892 (30%) Shipped within 7 - 13 working days

In this text, the small team of expert authors presents the field in a comprehensive and accessible manner that is well suited for students and junior researchers.
The result is a highly readable and systematically structured introduction to antimicrobial peptides, their structure, biological function and mode of action. The authors point the way towards a rational design of this potentially highly effective new class of clinical antibiotics on the brink of industrial application. They do this by discussing their design principles, target membranes and structure-activity relationships. The final part of the book describes recent successes in the application of peptides as anticancer agents.

Production of Membrane Proteins - Strategies for Expression and Isolation (Hardcover): Anne Skaja Robinson Production of Membrane Proteins - Strategies for Expression and Isolation (Hardcover)
Anne Skaja Robinson
R2,666 R1,879 Discovery Miles 18 790 Save R787 (30%) Shipped within 7 - 13 working days

Designed as a research-level guide to current strategies and methods of membrane protein production on the small to intermediate scale, this practice-oriented book provides detailed, step-by-step laboratory protocols as well as an explanation of the principles behind each method, together with a discussion of its relative advantages and disadvantages.
Following an introductory section on current challenges in membrane protein production, the book goes on to look at expression systems, emerging methods and approaches, and protein specific considerations.
Case studies illustrate how to select or sample the optimal production system for any desired membrane protein, saving both time and money on the laboratory as well as the technical production scale.
Unique in its coverage of "difficult" proteins with large membrane-embedded domains, proteins from extremophiles, peripheral membrane proteins, and protein fragments.

Peptide and Protein Design for Biopharmaceutical Applications (Hardcover): Knud Jensen Peptide and Protein Design for Biopharmaceutical Applications (Hardcover)
Knud Jensen
R2,648 R1,861 Discovery Miles 18 610 Save R787 (30%) Shipped within 7 - 13 working days

Peptides serve as effective drugs in the clinic today. However the inherent drawbacks of peptide structures can limit their efficacy as drugs. To overcome this researchers are developing new methods to create tailor-made' peptides and proteins with improved pharmacological properties. Design of Peptides and Proteins provides an overview of the experimental and computational methods for peptide and protein design, with an emphasis on specific applications for therapeutics and biomedical research. Topics covered include: * Computer modeling of peptides and proteins * Peptidomimetics * Design and synthesis of cyclic peptides * Carbohydrates in peptide and protein design * De novo design of peptides and proteins * Medical development applications * An extended case study - the design of insulin variants Design of Peptides and Proteins presents the state-of-the-art of this exciting approach for therapeutics, with contributions from international experts. It is an essential resource for academic and industrial scientists in the fields of peptide and protein drug design, biomedicine, biochemistry, biophysics, molecular modelling, synthetic organic chemistry and medicinal/pharmaceutical chemistry.

Nuclear Receptors - Methods and Experimental Protocols (Hardcover, 1st ed. 2019): Mostafa Z. Badr Nuclear Receptors - Methods and Experimental Protocols (Hardcover, 1st ed. 2019)
Mostafa Z. Badr
R3,546 R2,770 Discovery Miles 27 700 Save R776 (22%) Shipped within 7 - 12 working days

This volume presents valuable techniques for studying the class of ligand-activated transcription factors known as nuclear receptors. After a brief overview of the history of the field, chapters cover methods to detect the receptors and their mRNAs in various tissues, protocols to characterize nuclear receptor modulators and activities, their signaling and roles in certain pathogenesis, molecular modeling of nuclear receptor-ligand interactions, as well as the utility of informatics in the field of nuclear receptors. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Nuclear Receptors: Methods and Experimental Protocols seeks to aid researchers working toward furthering our understanding of these vital receptors and their role in numerous pathological conditions.

Structural Aspects Of Protein Synthesis (2nd Edition) (Paperback, 2nd Revised edition): Anders Liljas, Mans Ehrenberg Structural Aspects Of Protein Synthesis (2nd Edition) (Paperback, 2nd Revised edition)
Anders Liljas, Mans Ehrenberg
R1,736 R1,356 Discovery Miles 13 560 Save R380 (22%) Shipped within 4 - 8 working days

This highly illustrated book provides an up-to-date description of the structure and function of the translation system including ribosomes, tRNAs, translation factors, antibiotics and aminoacyl-tRNA synthetases.

Research on translation is undergoing rapid changes and is receiving significant attention as evidenced by the Nobel Prize in Chemistry 2009. The structural research by crystallography and cryo-EM forms part of an interactive framework that involves biochemistry and molecular computation. The book provides a comprehensive overview of translation in light of the structural results. It is a valuable resource for scientists in this and related fields, as well as for students taking courses with a focus on translation.

There is no other book in this field currently except the previous edition of this book. The authors have for a long time worked in the field of structure and function of the translation system.

RNA Purification and Analysis - Sample Preparation, Extraction, Chromatography (Hardcover): Douglas T. Gjerde, Lee Hoang, David... RNA Purification and Analysis - Sample Preparation, Extraction, Chromatography (Hardcover)
Douglas T. Gjerde, Lee Hoang, David Hornby
R2,814 R1,975 Discovery Miles 19 750 Save R839 (30%) Shipped within 7 - 13 working days

This first book on the market covers the many new and important RNA species discovered over the past five years, explaining current methods for the enrichment, separation and purification of these novel RNAs. Building up from general principles of RNA biochemistry and biophysics, this book addresses the practical aspects relevant to the laboratory researcher throughout, while discussing the performance and potential problems of the methods discussed. An appendix contains a glossary with the important terms and techniques used in RNA analysis. By explaining the basic and working principles of the methods, the book allows biochemists and molecular biologists to gain much more expertise than by simply repeating a pre-formulated protocol, enabling them to select the procedure and materials best suited to the RNA analysis task at hand. As a result, they will be able to develop new protocols where needed and optimize and fine-tune the general purpose standard protocols that come with the purification equipment and instrumentation.

Whey Protein Production, Chemistry, Functionality, and Applications (Hardcover): Mingruo Guo Whey Protein Production, Chemistry, Functionality, and Applications (Hardcover)
Mingruo Guo
R3,239 R2,268 Discovery Miles 22 680 Save R971 (30%) Shipped within 7 - 13 working days

An up-to-date overview of the dynamic field of whey protein utilization Whey Protein Production, Chemistry, Functionality and Applications explores the science and technology behind the rapidly increasing popularity of this most versatile of dairy by-products. With its richly nutritious qualities, whey protein has been widely used in the food industry for many years. The last decade has, however, seen manufacturers develop many innovative and exciting new applications for it, both in food and other areas. Taking account of these advances, this insightful work offers a full explanation of the technological and chemical breakthroughs that have made whey protein more in-demand than ever before. Topics covered include manufacturing technologies, thermal and chemical modifications, non-food uses, denaturation and interactions, and more. In its broad scope, the book encompasses: An up-to-date overview of recent developments and new applications Breakdowns of the chemical, nutritional, and functional properties of whey protein Commentary on the current and future outlooks of the whey protein market Examinations of the methods and manufacturing technologies that enable whey protein recovery A full guide to the numerous applications of whey protein in food production and other industries Whey Protein Production, Chemistry, Functionality and Applications is an unparalleled source of information on this highly adaptable and much sought-after commodity, and is essential reading for food and dairy scientists, researchers and graduate students, and professionals working in the food formulation and dairy processing industries.

The Protein Chart (Paperback): Richard Charles Garratt, Christine A. Orengo The Protein Chart (Paperback)
Richard Charles Garratt, Christine A. Orengo
R242 R185 Discovery Miles 1 850 Save R57 (24%) Shipped within 7 - 13 working days

What the Periodic Table did for the visualization of chemical concepts, this chart will achieve for structural biology. This truly innovative product addresses a growing need in the scientific community -- making the entire spectrum of protein structures instantly accessible on one handy chart. By way of a clever arrangement into rows and columns, this is much more than a simple field guide to individual protein structures: It is also an invaluable aid to understanding the principles behind protein structure diversity.
There is simply no better tool to introduce students to the secrets of proteins.

PlantOmics: The Omics of Plant Science (Hardcover, 2015 ed.): Debmalya Barh, Muhammad Sarwar Khan, Eric Davies PlantOmics: The Omics of Plant Science (Hardcover, 2015 ed.)
Debmalya Barh, Muhammad Sarwar Khan, Eric Davies
R4,467 R3,972 Discovery Miles 39 720 Save R495 (11%) Shipped within 7 - 12 working days

PlantOmics: The Omics of Plant Science provides a comprehensive account of the latest trends and developments of omics technologies or approaches and their applications in plant science. Thirty chapters written by 90 experts from 15 countries are included in this state-of-the-art book. Each chapter describes one topic/omics such as: omics in model plants, spectroscopy for plants, next generation sequencing, functional genomics, cyto-metagenomics, epigenomics, miRNAomics, proteomics, metabolomics, glycomics, lipidomics, secretomics, phenomics, cytomics, physiomics, signalomics, thiolomics, organelle omics, micro morphomics, microbiomics, cryobionomics, nanotechnology, pharmacogenomics, and computational systems biology for plants. It provides up to date information, technologies, and their applications that can be adopted and applied easily for deeper understanding plant biology and therefore will be helpful in developing the strategy for generating cost-effective superior plants for various purposes. In the last chapter, the editors have proposed several new areas in plant omics that may be explored in order to develop an integrated meta-omics strategy to ensure the world and earth's health and related issues. This book will be a valuable resource to students and researchers in the field of cutting-edge plant omics.

Structural Proteomics - High-Throughput Methods (Hardcover, 2nd ed. 2015): Raymond J. Owens Structural Proteomics - High-Throughput Methods (Hardcover, 2nd ed. 2015)
Raymond J. Owens
R3,843 R3,093 Discovery Miles 30 930 Save R750 (20%) Shipped within 7 - 12 working days

This updated and expanded volume reflects the current state of the structural protein field with improved and refined protocols that have been applied to particularly challenging proteins, notably integral membrane proteins and multi-protein complexes. Structural Proteomics: High-Throughput Methods, Second Edition begins by exploring the resources available for curation, annotation, and structure prediction in silico, and continues with methods for sample preparation of both proteins and crystals, as well as structural characterization techniques. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and up-to-date, Structural Proteomics: High-Throughput Methods, Second Edition will aid researchers in expanding our knowledge of this vital and expansive area of protein science.

Osmolytes and Plants Acclimation to Changing Environment: Emerging Omics Technologies (Hardcover, 1st ed. 2016): Noushina... Osmolytes and Plants Acclimation to Changing Environment: Emerging Omics Technologies (Hardcover, 1st ed. 2016)
Noushina Iqbal, Rahat Nazar, Nafees A. Khan
R2,940 R2,653 Discovery Miles 26 530 Save R287 (10%) Shipped within 7 - 12 working days

The continual change in climatic conditions induces a series of adaptations in plants to suit the unfavorable conditions for sustainable agriculture. For sustainable agriculture, it is important to unravel the precise mechanism(s) that disturb the homeostatic equilibrium at cellular and molecular level and also to enhance understanding to build strategies for the tolerance of plants. Osmolytes have long been identified as pivotal abiotic stress busters because of their role in plants in overcoming extremely harsh environmental conditions. This edited compilation attempts to put forth the scattered knowledge on osmolytes and their role in abiotic stress tolerance together and disseminate as a package to deal with the problems of lower productivity under stressful environment. It will enhance the understanding on osmolytes function and bioengineering of plants for abiotic stress tolerance. The book covers very interesting topics dealing with various osmolytes and the mechanistic approach for abiotic stress tolerance to pave the path of agricultural scientists, breeders for developing high yielding sustainable transgenic crops.

Plant ABC Transporters (Hardcover, 2014 ed.): Markus Geisler Plant ABC Transporters (Hardcover, 2014 ed.)
Markus Geisler
R4,124 R3,322 Discovery Miles 33 220 Save R802 (19%) Shipped within 7 - 12 working days

This book is devoted to the fascinating superfamily of plant ATP-binding cassette (ABC) transporters and their variety of transported substrates. It highlights their exciting biological functions, covering aspects ranging from cellular detoxification, through development, to symbiosis and defense. Moreover, it also includes a number of chapters that center on ABC transporters from non-Arabidopsis species.

ABC proteins are ubiquitous, membrane-intrinsic transporters that catalyze the primary (ATP-dependent) movement of their substrates through biological membranes. Initially identified as an essential aspect of a vacuolar detoxification process, genetic work in the last decade has revealed an unexpectedly diverse variety of ABC transporter substrates, which include not only xenobiotic conjugates, but also heavy metals, lipids, terpenoids, lignols, alkaloids and organic acids.

The discovery that members of the ABCB and ABCG family are involved in the movement of phytohormones has further sparked their exploration and provided a new understanding of the whole family. Accordingly, the trafficking, regulation and structure-function of ABCB-type auxin transporters are especially emphasized in this book.

Chromogranins: from Cell Biology to Physiology and Biomedicine (Hardcover, 1st ed. 2017): Bruno Tota Chromogranins: from Cell Biology to Physiology and Biomedicine (Hardcover, 1st ed. 2017)
Bruno Tota
R3,598 R2,848 Discovery Miles 28 480 Save R750 (21%) Shipped within 7 - 12 working days

The volume is designed to provide an integrated overview of the results from the last fifteen years of research on Chromogranins in relation to cell biology, physiology and biomedicine. The different chapters highlight novel activities of these proteins, including their role in granule biogenesis, hormone co-storage, stimulus-processing-secretion coupling, autonomic sympathetic/parasympathetic balance, immune and cardiocirculatory function, and the response to stress. Biomedical aspects are also illustrated with focus on the prognostic and diagnostic significance of Chromogranin in the presence of tumors, cardiovascular diseases and inflammatory conditions. The volume is of interest for laboratory and clinical scientists, PhD and Post-doc students that will be inspired to go deep inside the molecular, biochemical, physiological, pharmacological and clinical aspects of these fascinating multifaceted proteins.

G Protein-Coupled Receptors - Structure, Signaling, and Physiology (Hardcover): Sandra Siehler, Graeme Milligan G Protein-Coupled Receptors - Structure, Signaling, and Physiology (Hardcover)
Sandra Siehler, Graeme Milligan
R2,696 Discovery Miles 26 960 Shipped within 7 - 12 working days

Provides a comprehensive overview of recent discoveries and current understandings of G protein-coupled receptors (GPCRs). Recent advances include the first mammalian non-rhodopsin GPCR structures and reconstitution of purified GPCRs into membrane discs for defined studies, novel signaling features including oligomerization, and advances in understanding the complex ligand pharmacology and physiology of GPCRs, in new assay technologies and drug targeting. The authors take time to detail the importance of the pathophysiological function and drug targeting of GPCRs, specifically ss-adrenoceptors in cardiovascular and respiratory diseases, metabotropic glutamate receptors in CNS disorders, S1P receptors in the immune system, and Wnt/Frizzled receptors in osteoporosis. This book will be invaluable to researchers and graduate students in academia and industry who are interested in the GPCR field.

Peptides as Drugs - Discovery and Development (Hardcover): Bernd Groner Peptides as Drugs - Discovery and Development (Hardcover)
Bernd Groner
R4,424 R3,086 Discovery Miles 30 860 Save R1,338 (30%) Shipped within 7 - 13 working days

By covering the full spectrum of topics relevant to peptidic drugs, this timely handbook serves as an introductory reference for both drug developers and biomedical researchers interested in pharmaceutically active peptides, presenting both the advantages and challenges associated with this molecular class.
The first part discusses current approaches to developing pharmaceutically active peptides, including case studies of the use of peptidic drugs in cancer and AIDS therapy. The second part surveys strategies for the development and targeting of peptidic drugs.
With its integration of biochemical, pharmaceutical and clinical research, this work reveals the full picture of modern peptide drug research in a single volume, making it an invaluable reference for medicinal chemists, biochemists, biotechnologists, and those in the pharmaceutical and biotechnological industries.

Proteomics Sample Preparation (Hardcover): Jorg Von Hagen Proteomics Sample Preparation (Hardcover)
Jorg Von Hagen
R3,007 R2,115 Discovery Miles 21 150 Save R892 (30%) Shipped within 7 - 13 working days

This long-awaited first guide to sample preparation for proteomics studies overcomes a major bottleneck in this fast growing technique within the molecular life sciences. By addressing the topic from three different angles -- sample, method and aim of the study -- this practical reference has something for every proteomics researcher. Following an introduction to the field, the book looks at sample preparation for specific techniques and applications and finishes with a section on the preparation of sample types. For each method described, a summary of the pros and cons is given, as well as step-by-step protocols adaptable to any specific proteome analysis task.

Protein-Ligand Interactions (Hardcover): Holger Gohlke Protein-Ligand Interactions (Hardcover)
Holger Gohlke; Series edited by Raimund Mannhold, Hugo Kubinyi, Gerd Folkers
R3,758 R2,630 Discovery Miles 26 300 Save R1,128 (30%) Shipped within 7 - 13 working days

Innovative and forward-looking, this volume focuses on recent achievements in this rapidly progressing field and looks at future potential for development. The first part provides a basic understanding of the factors governing protein-ligand interactions, followed by a comparison of key experimental methods (calorimetry, surface plasmon resonance, NMR) used in generating interaction data. The second half of the book is devoted to insilico methods of modeling and predicting molecular recognition and binding, ranging from first principles-based to approximate ones. Here, as elsewhere in the book, emphasis is placed on novel approaches and recent improvements to established methods. The final part looks at unresolved challenges, and the strategies to address them. With the content relevant for all drug classes and therapeutic fields, this is an inspiring and often-consulted guide to the complexity of protein-ligand interaction modeling and analysis for both novices and experts.

Proteins - Biochemistry and Biotechnology (Hardcover, 2nd Edition): Gary Walsh Proteins - Biochemistry and Biotechnology (Hardcover, 2nd Edition)
Gary Walsh
R2,241 R1,584 Discovery Miles 15 840 Save R657 (29%) Shipped within 7 - 13 working days

"Proteins Biochemistry and Biotechnology" 2e is a definitive source of information for all those interested in protein science, and particularly the commercial production and isolation of specific proteins, and their subsequent utilization for applied purposes in industry and medicine.Fully updated throughout with new or fundamentally revised sections on proteomics as, bioinformatics, protein glycosylation and engineering, well as sections detailing advances in upstream processing and newer protein applications such as enzyme-based biofuel production this new edition has an increased focus on biochemistry to ensure the balance between biochemisty and biotechnology, enhanced with numerous case studies.This second edition is an invaluable text for undergraduates of biochemistry and biotechnology but will also be relevant to students of microbiology, molecular biology, bioinformatics and any branch of the biomedical sciences who require a broad overview of the various medical, diagnostic and industrial uses of proteins. - Provides a comprehensive overview of all aspects of protein biochemisty and protein biotechnology- Includes numerous case studies - Increased focus on protein biochemistry to ensure balance between biochemisty and biotechnology- Includes new section focusing on proteomics as well as sections detailing protein function and enzyme-based biofuel production"With the potential of a standard reference source on the topic, any molecular biotechnologist will profit greatly from having this excellent book. " ("Engineering in Life Sciences," 2004; Vol 5; No. 5)"Few texts would be considered competitors, and none compare favorably." ("Biochemistry and Molecular Education," July/August 2002) ..".The book is well written, making it informative and easy to read..." ("The Biochemist," June 2002)

Single Molecule Dynamics in Life Science (Hardcover): Toshio Yanagida, Yoshiharu Ishii Single Molecule Dynamics in Life Science (Hardcover)
Toshio Yanagida, Yoshiharu Ishii
R5,108 R3,561 Discovery Miles 35 610 Save R1,547 (30%) Shipped within 7 - 13 working days

In this first comprehensive resource to cover the application of single molecule techniques to biological measurements, the pioneers in the field show how to both set up and interpret a single molecule experiment.
Following an introduction to single molecule measurements and enzymology, the expert authors consider molecular motors and mechanical properties before moving on to the applications themselves. Detailed discussions of studies on protein enzymes, ribozymes and nucleic acids are also included.

Peptides from A to Z - A Concise Encyclopedia (Hardcover): Hans-Dieter Jakubke, Norbert Sewald Peptides from A to Z - A Concise Encyclopedia (Hardcover)
Hans-Dieter Jakubke, Norbert Sewald
R3,761 R2,633 Discovery Miles 26 330 Save R1,128 (30%) Shipped within 7 - 13 working days

This mini-encyclopedia contains more than 1,500 alphabetical entries from the entire field of peptide science in one handy volume, as well as the technical terms, acronyms and concepts used in peptide chemistry. It also features the complete sequence of more than 800 peptides, numerous illustrations and numerous cross-references.
Areas covered include:
- biological peptides and small proteins
- peptide hormones
- pharmaceutical peptides
- peptide antibiotics
- peptide inhibitors
- peptide reagents
- peptide tags
- structural classes
- synthesis and purification
- analytical methods
- proteomics and peptidomics.
Condensed yet accessible, only essential information is displayed, extensively linked via references to the recent scientific literature for further study.

Agricultural Proteomics Volume 1 - Crops, Horticulture, Farm Animals, Food, Insect and Microorganisms (Hardcover, 1st ed.... Agricultural Proteomics Volume 1 - Crops, Horticulture, Farm Animals, Food, Insect and Microorganisms (Hardcover, 1st ed. 2016)
Ghasem Hosseini Salekdeh
R3,839 R3,167 Discovery Miles 31 670 Save R672 (18%) Shipped within 7 - 12 working days

This book will cover several topics to elaborate how proteomics may enhance agricultural productivity. These include crop and food proteomics, farm animal proteomics, aquaculture, microorganisms and insect proteomics. It will also cover several technical advances, which may address the current need for comprehensive proteome analysis.An emerging field of the proteomics aim is to integrate knowledge from basic sciences and to translate it into agricultural applications to solve issues related to economic values of farm animals, crops, food security, health, and energy sustainability. Given the wealth of information generated and to some extent applied in agriculture, there is the need for more efficient and broader channels to freely disseminate the information to the scientific community.

Protein-protein Complexes: Analysis, Modeling And Drug Design (Paperback): Martin Zacharias Protein-protein Complexes: Analysis, Modeling And Drug Design (Paperback)
Martin Zacharias
R1,522 R1,420 Discovery Miles 14 200 Save R102 (7%) Shipped within 7 - 12 working days

Given the immense progress achieved in elucidating protein protein complex structures and in the field of protein interaction modeling, there is great demand for a book that gives interested researchers/students a comprehensive overview of the field. This book does just that. It focuses on what can be learned about protein protein interactions from the analysis of protein protein complex structures and interfaces. What are the driving forces for protein protein association? How can we extract the mechanism of specific recognition from studying protein protein interfaces? How can this knowledge be used to predict and design protein protein interactions (interaction regions and complex structures)? What methods are currently employed to design protein protein interactions, and how can we influence protein protein interactions by mutagenesis and small-molecule drugs or peptide mimetics? The book consists of about 15 review chapters, written by experts, on the characterization of protein protein interfaces, structure determination of protein complexes (by NMR and X-ray), theory of protein protein binding, dynamics of protein interfaces, bioinformatics methods to predict interaction regions, and prediction of protein protein complex structures (docking and homology modeling of complexes, etc.) and design of protein protein interactions. It serves as a bridge between studying/analyzing protein protein complex structures (interfaces), predicting interactions, and influencing/designing interactions.

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