Please note that the content of this book primarily consists of
articles available from Wikipedia or other free sources online. In
enzymology, a 2-dehydro-3-deoxyglucarate aldolase (EC 188.8.131.52) is
an enzyme that catalyzes the chemical reaction
2-dehydro-3-deoxy-D-glucarate \rightleftharpoons pyruvate +
tartronate semialdehyde. Hence, this enzyme has one substrate,
2-dehydro-3-deoxy-D-glucarate, and two products, pyruvate and
tartronate semialdehyde. This enzyme belongs to the family of
lyases, specifically the aldehyde-lyases, which cleave
carbon-carbon bonds. The systematic name of this enzyme class is
(pyruvate-forming). Other names in common use include
2-keto-3-deoxyglucarate aldolase, alpha-keto-beta-deoxy-D-glucarate
aldolase, and 2-dehydro-3-deoxy-D-glucarate
tartronate-semialdehyde-lyase. This enzyme participates in
ascorbate and aldarate metabolism.
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Aaron Philippe Toll
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