The one-stop reference to pharmacogenetics and its impact on
pharmaceuticals, therapeutics, and clinical practices
Pharmacogenetics and Individualized Therapy offers thorough
coverage of the study of the genetic determinants of drug response
at the single gene level-and its impact on pharmaceuticals,
therapeutics, and clinical practice. Providing an overview of the
molecular basis of pharmacogenetics, the book helps readers
understand the implications of genetic variability on
pharmacokinetics and pharmacodynamics, as well as other aspects
such as adverse drug reactions. Providing coverage of specific
disease areas, including cardiovascular concerns, cancer and
asthma/COPD, transplantation, and pain medication, the book also
looks at the clinical practices, along with the psychiatric and
ethical issues that have come to dominate conversation about
The technological applications of pharmacogenetics, including
genotyping, drug disposition (metabolism and enzymes), and the
impact of this research on the pharmaceutical industry and
regulatory matters are all addressed in chapters by internationally
recognized leaders from both academia and industry.
Including chapters on specific therapeutic areas and clinical
aspects, Pharmacogenetics and Individualized Therapy helps readers,
whether they're students or researchers, to understand the
implications of genetic variability on pharmacokinetics and
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