Cell Death Signaling in Cancer Biology and Treatment (Hardcover, 2013 ed.)


A key goal in the treatment of cancer is to achieve selective and efficient killing of tumor cells. The aim of "Cell Death Signaling in Cancer Biology and Treatment" is to describe state-of-the-art approaches and future opportunities for achieving this goal by targeting mechanisms and pathways that regulate cancer cell death. In this book, molecular defects in cell death signaling that characterize cancer cells, including dysregulation of cell death due to overexpression/hyperactivation of oncoproteins, as well as the loss of tumor suppressor proteins will be described. The potential for targeting microRNAs will be discussed. Multiple chapters will describe preclinical and clinical approaches that are currently being used to target epigenetic modifications, DNA repair pathways, and protein chaperones, as a means of provoking tumor cell death. Finally, the development and application of novel agents and approaches for targeting specific components of cell death signaling pathways and machinery will be reviewed.

R5,849

Or split into 4x interest-free payments of 25% on orders over R50
Learn more

Discovery Miles58490
Mobicred@R548pm x 12* Mobicred Info
Free Delivery
Delivery AdviceShips in 10 - 15 working days


Toggle WishListAdd to wish list
Review this Item

Product Description

A key goal in the treatment of cancer is to achieve selective and efficient killing of tumor cells. The aim of "Cell Death Signaling in Cancer Biology and Treatment" is to describe state-of-the-art approaches and future opportunities for achieving this goal by targeting mechanisms and pathways that regulate cancer cell death. In this book, molecular defects in cell death signaling that characterize cancer cells, including dysregulation of cell death due to overexpression/hyperactivation of oncoproteins, as well as the loss of tumor suppressor proteins will be described. The potential for targeting microRNAs will be discussed. Multiple chapters will describe preclinical and clinical approaches that are currently being used to target epigenetic modifications, DNA repair pathways, and protein chaperones, as a means of provoking tumor cell death. Finally, the development and application of novel agents and approaches for targeting specific components of cell death signaling pathways and machinery will be reviewed.

Customer Reviews

No reviews or ratings yet - be the first to create one!

Product Details

General

Imprint

Springer-Verlag New York

Country of origin

United States

Series

Cell Death in Biology and Diseases

Release date

November 2012

Availability

Expected to ship within 10 - 15 working days

First published

2013

Editors

Dimensions

235 x 155 x 28mm (L x W x T)

Format

Hardcover

Pages

408

Edition

2013 ed.

ISBN-13

978-1-4614-5846-3

Barcode

9781461458463

Categories

LSN

1-4614-5846-3



Trending On Loot