Lysosomal Disorders of Brain details recent advances in the molecular and cellular pathologies of these diseases and in the development of effective therapies. After an overview of the biology of the endosomal-lysosomal system and the types of diseases resulting from defects in this system, the book describes in detail the molecular mechanisms of storage, model systems and pathophysiological mechanisms, and finally, new advances toward treatment. With each chapter written by leading experts in their field, this book will be valuable for scientists and clinicians in helping them understand the role of lysosomes in normal cells and mechanisms underlying these disorders, how they can be diagnosed, and the treatment options that are currently available.
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Lysosomal Disorders of Brain details recent advances in the molecular and cellular pathologies of these diseases and in the development of effective therapies. After an overview of the biology of the endosomal-lysosomal system and the types of diseases resulting from defects in this system, the book describes in detail the molecular mechanisms of storage, model systems and pathophysiological mechanisms, and finally, new advances toward treatment. With each chapter written by leading experts in their field, this book will be valuable for scientists and clinicians in helping them understand the role of lysosomes in normal cells and mechanisms underlying these disorders, how they can be diagnosed, and the treatment options that are currently available.
Imprint | Oxford UniversityPress |
Country of origin | United Kingdom |
Release date | February 2004 |
Availability | Supplier out of stock. If you add this item to your wish list we will let you know when it becomes available. |
First published | March 2004 |
Editors | Frances Platt, Steven Walkley |
Dimensions | 248 x 173 x 31mm (L x W x T) |
Format | Hardcover |
Pages | 478 |
Edition | New |
ISBN-13 | 978-0-19-850878-6 |
Barcode | 9780198508786 |
Categories | |
LSN | 0-19-850878-6 |