Deprotonation (Paperback)

High Quality Content by WIKIPEDIA articles! Deprotonation is the removal of a proton (H+) from a molecule, forming the conjugate base.The relative ability of a molecule to give up a proton is measured by its pKa value. A low pKa value indicates that the compound is acidic and will easily give up its proton to a base. The pKa of a compound is determined by many things, but most significantly it is impacted by the stability of the conjugate base, that is mainly determined by the ability (or inability) of the conjugated base to stabilize the negative charge.