High Quality Content by WIKIPEDIA articles! Kir6.2 is a major
subunit of the ATP-sensitive K+ channel, an inward-rectifier
potassium ion channel. The gene encoding the channel is called
KCNJ11 and mutations in this gene are associated with congenital
hyperinsulinism. It is an integral membrane protein. The protein,
which has a greater tendency to allow potassium to flow into a cell
rather than out of a cell, is controlled by G-proteins and is found
associated with the sulfonylurea receptor (SUR) to constitute the
ATP-sensitive K+ channel.
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