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Starling's "Law of the Heart" Revisited (Hardcover) Loot Price: R1,466
Discovery Miles 14 660
You Save: R132 (8%)
Starling's "Law of the Heart" Revisited (Hardcover): H.E.D.J.Ter Keurs, Mark I.M. Noble, I.M. Mark

Starling's "Law of the Heart" Revisited (Hardcover)

H.E.D.J.Ter Keurs, Mark I.M. Noble, I.M. Mark

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List price R1,598 Loot Price R1,466 Discovery Miles 14 660 | Repayment Terms: R136 pm x 12* You Save R132 (8%)

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H. E. D. J. TER KEURS & M. I. M. NOBLE The "Starling's Law of the Heart" and "The Frank-Starling Mechanism" have long been the cornerstone of cardiac mechanical physiology. It is often forgotten that Frank and Starling carried out fundamentally different exper iments. Frankl measured the isovolumic pressure developed by frog heart at different volumes. He therefore discovered the pressure-volume-volume rela tionship which depends directly on the force-length relationship of the 2 sarcomeres. Starling,3 studied cardiac shortening as manifest by cardiac output and its relationship to end-diastolic conditions as manifest by right atrial pressure. Thus he was studying the ability of cardiac muscle to shorten more at a given load from a greater initial length. Starling in the promulga 4 tions of his law implied a common mechanism for these two phenomena and spoke of the "energy liberated" being a function of initial muscle fiber length. However, there has been much confusion about the interrelationship between the two different aspects studied by Frank and Starling. The 1960s saw the era of isolated cardiac muscle mechanics, beginning with 5 the paper of Abbott and Mommaerts. Whole muscle length-tension relations were equated with sarcomere-length-tension relations by fixation of muscle at a particular point on the curve and determination of sarcomere length by electronmicroscopy."

General

Imprint: Kluwer Academic Publishers
Country of origin: United States
Release date: October 1988
First published: 1988
Editors: H.E.D.J.Ter Keurs • Mark I.M. Noble • I.M. Mark
Dimensions: 250 x 190 x 13mm (L x W x T)
Format: Hardcover
Pages: 168
ISBN-13: 978-0-89838-382-9
Categories: Books > Medicine > Clinical & internal medicine
Books > Medicine > Clinical & internal medicine > Cardiovascular medicine
LSN: 0-89838-382-X
Barcode: 9780898383829

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