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MAIT Cells - Methods and Protocols (Hardcover, 1st ed. 2020) Loot Price: R4,323
Discovery Miles 43 230
MAIT Cells - Methods and Protocols (Hardcover, 1st ed. 2020): Helen Kaipe, Isabelle Magalhaes

MAIT Cells - Methods and Protocols (Hardcover, 1st ed. 2020)

Helen Kaipe, Isabelle Magalhaes

Series: Methods in Molecular Biology, 2098

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Loot Price R4,323 Discovery Miles 43 230 | Repayment Terms: R399 pm x 12*

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This volume focuses on various methods used by researchers to study mucosal-associated invariant T (MAIT) cells in the aspects described below. The chapters are organized into Four Parts: part One looks at the function and importance of MAIT cells in health and disease. It covers methods to isolate and characterize MAIT cells from human tissues including liver, colon tumors, placenta and decidua, and endometrium. Part Two discusses MR1 independent stimulation, and looks at the activation of MAIT cells by different stimulatory agents. Part Three describes various methods to develop tools to analyze, monitor, and generate MAIT cells in vitro, including the production of MR1-tetramers and how they can be loaded with bacterial antigens and used for the detection of MAIT cells. The last part covers the use of murine models to study MAIT cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and comprehensive, MAIT Cells: Methods and Protocols is a valuable resource for anyone interested in learning more about this developing field. Chapters 9 and 17 are open access under a CC BY 4.0 license.

General

Imprint: Springer-Verlag New York
Country of origin: United States
Series: Methods in Molecular Biology, 2098
Release date: December 2019
First published: 2020
Editors: Helen Kaipe • Isabelle Magalhaes
Dimensions: 254 x 178mm (L x W)
Format: Hardcover
Pages: 310
Edition: 1st ed. 2020
ISBN-13: 978-1-07-160206-5
Categories: Books > Medicine > Clinical & internal medicine
Books > Science & Mathematics > Biology, life sciences
Books > Medicine > Clinical & internal medicine > Diseases & disorders
Books > Science & Mathematics > Biology, life sciences > Cellular biology
Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology
Books > Science & Mathematics > Biology, life sciences > Cellular biology > General
Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology > General
LSN: 1-07-160206-3
Barcode: 9781071602065

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