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Books > Science & Mathematics > Biology, life sciences > Biochemistry > Proteins

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ADME and Translational Pharmacokinetics / Pharmacodynamics of Therapeutic Proteins - Applications in Drug Discovery and Development (Hardcover) Loot Price: R1,909
Discovery Miles 19 090
You Save: R792 (29%)
ADME and Translational Pharmacokinetics / Pharmacodynamics of Therapeutic Proteins - Applications in Drug Discovery and...

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ADME and Translational Pharmacokinetics / Pharmacodynamics of Therapeutic Proteins - Applications in Drug Discovery and Development (Hardcover)

Honghui Zhou, Frank-Peter Theil

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List price R2,701 Loot Price R1,909 Discovery Miles 19 090 | Repayment Terms: R178 pm x 12* You Save R792 (29%)

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With an emphasis on the fundamental and practical aspects of ADME for therapeutic proteins, this book helps readers strategize, plan and implement translational research for biologic drugs. Details cutting-edge ADME (absorption, distribution, metabolism and excretion) and PKPD (pharmacokinetic / pharmacodynamics) modeling for biologic drugs Combines theoretical with practical aspects of ADME in biologic drug discovery and development and compares innovator biologics with biosimilar biologics and small molecules with biologics, giving a lessons-learned perspective Includes case studies about leveraging ADME to improve biologics drug development for monoclonal antibodies, fusion proteins, pegylated proteins, ADCs, bispecifics, and vaccines Presents regulatory expectations and industry perspectives for developing biologic drugs in USA, EU, and Japan Provides mechanistic insight into biodistribution and target-driven pharmacokinetics in important sites of action such as tumors and the brain

General

Imprint: John Wiley & Sons
Country of origin: United States
Release date: 2016
Authors: Honghui Zhou • Frank-Peter Theil
Dimensions: 291 x 222 x 31mm (L x W x T)
Format: Hardcover
Pages: 472
ISBN-13: 978-1-118-89864-2
Categories: Books > Medicine > Other branches of medicine
Books > Science & Mathematics > Biology, life sciences
Books > Medicine > Other branches of medicine > Pharmacology
Books > Science & Mathematics > Biology, life sciences > Biochemistry
Books > Medicine > Other branches of medicine > Pharmacology > General
Books > Science & Mathematics > Biology, life sciences > Biochemistry > Proteins
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LSN: 1-118-89864-8
Barcode: 9781118898642

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