Toxicogenomics is a new, dynamic and very promising field that can
help optimize toxicity analyses and streamline research into active
substances. It is of interest not only for basic research and
development, but also from a legal and ethical perspective. Here,
experts from all the fields mentioned will find solid information
provided by an international team of experienced authors. With its
approach as an interdisciplinary overview, it will prove
particularly useful for all those needing to develop appropriate
The authors work for major research institutions, such as the
Fraunhofer Institute of Toxicology and Experimental Medicine
(Germany), the German Cancer Research Center, the National
Institute of Environmental Health Science (USA), the National
Institute of Health Science (Japan) or for companies like
Affymetrix, Altana Pharma, Bayer, Boehringer Ingelheim, Bruker,
Merck, Nimblegen, Novartis, and Syngenta. Coverage ranges from the
technology platforms applied, including DNA arrays or proteomics,
via the bioinformatics tools required, right up to applications of
toxicogenomics presented in numerous case studies, while also
including an overview of national programs and initiatives as well
as regulatory perspectives.
Walter Rosenthal, Director of the Research Institute for
Molecular Pharmacology in Berlin, praises the book thus: "I would
like to congratulate the publishers of this handbook, one that
deals with a extremely hot topic. They have succeeded in gaining as
authors leading representatives from this field. The Handbook
impressively shows how modern genomic research is leading to rapid
advances and new insights within toxicology."
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