Books > Science & Mathematics > Biology, life sciences > Zoology & animal sciences
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Discovery Miles 7 100
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Tubulin-specific chaperone E is a protein that in humans is encoded
by the TBCE gene.Cofactor E is one of four proteins (cofactors A,
D, E, and C) involved in the pathway leading to correctly folded
beta-tubulin from folding intermediates. Cofactors A and D are
believed to play a role in capturing and stabilizing beta-tubulin
intermediates in a quasi-native confirmation. Cofactor E binds to
the cofactor D/beta-tubulin complex; interaction with cofactor C
then causes the release of beta-tubulin polypeptides that are
committed to the native state. Two transcript variants encoding the
same protein have been found for this gene.
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