Compounding Guide for Ophthalmic Preparations (Paperback)

Pharmacists and ophthalmologists now have a complete guide to preparing quality compounded ophthalmic medications. The Compounding Guide for Ophthalmic Preparations is a single-source, user-friendly reference that contains 176 drug monographs. Author Linda F. McElhiney performed a rigorous search of pharmacy literature to glean the necessary information to compound quality ophthalmic preparations. She then put the "puzzle pieces" together to develop suitable formulas. The drug monographs in this book provide up-to-date stability information based on reliable references and published stability studies. Chapters 1-3 discuss compounding guidelines for sterile ophthalmic preparations, sterilizing techniques, and quality assurance procedures. This information is based on the United States Pharmacopeia (USP) standards. Chapter 4 provides an extensive explanation of the components of sterile ophthalmic preparations: preservatives, antioxidants, viscosity agents, toxicity, clarity, pH and buffers, vehicles and bases, and active pharmaceutical ingredients. Chapters 5-9 provide background information on a particular type of ophthalmic preparation, hazardous preparations, topical preparations, ocular injections, topical ointments, and blood-derived preparations, respectively followed by step-by-step instructions for commonly compounded ophthalmic drugs. It includes an appendix that provides sodium equivalent values for various concentrations of drugs commonly used in ophthalmic preparations. Each drug monograph provides information on ingredients, preparation, packaging and labeling, beyond-use date, therapeutic use, quality control parameters, special notes, and reference citations for clinical evidence.