This book is designed to assist physicians in the everyday
management of hypertensive patients, with a particular focus on
difficult-to-treat and resistant hypertension. The selected
clinical cases are representative of the patients who are seen in
the "real world", rather than rare clinical cases, and provide
examples of management according to current international
guidelines. The scenarios considered include not only cases in
which arterial hypertension is truly resistant but also instances
of pseudo-resistant hypertension, including cases in which
resistance is related to comorbidities, concomitant treatments, or
the use of drugs. The ultimate objective is to provide paradigmatic
examples of evidence-based approaches to difficult-to-treat
patients that will help physicians to select the most appropriate
diagnostic tools and evidence-based treatment strategy for each
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