Steroid dimers are an important group of compounds produced by
various marine organisms, and also synthesized in the laboratories.
This group of compounds possesses various pharmacological and
biological properties, and can also be used to create "molecular
umbrellas" for drug delivery.
"Steroid Dimers: Chemistry and Applications in Drug Design and
Delivery" provides an up-to-date overview on the chemistry and
applications of steroid dimers of natural and synthetic origins.
The book includes easy-to-follow synthetic protocols for various
classes of important dimeric steroids, source details, valuable
spectroscopic data and depiction of unique structural features of
natural steroidal dimers, and the Structure-Activity-Relationships
(SARs) of some pharmacologically active dimeric steroids. Topics
covered include: introduction to steroid dimers synthesis and
chemistry of noncyclic and cyclic steroid dimersnaturally occurring
steroid dimers - cephalostatins, ritterazines and
crellastatinsbiological and pharmacological functions of steroid
dimers and their application in drug design and discoverysteroid
dimers as "molecular umbrellas" for drug delivery"Steroid Dimers:
Chemistry and Applications in Drug Design and Delivery" is an
essential guide to this important class of natural and synthetic
compounds for researchers and students of natural products
chemistry and biochemistry, synthetic organic and medicinal
chemistry, and drug design, discovery and delivery.
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