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Annual Reports in Combinatorial Chemistry and Molecular Diversity Volume 1 (Online resource)
Annual Reports in Combinatorial Chemistry and Molecular Diversity Volume 1 (Online resource): Walter H. Moos

Annual Reports in Combinatorial Chemistry and Molecular Diversity Volume 1 (Online resource)

Walter H. Moos; Edited by Michael R. Pavia, B.K. Kay, A.D. Ellington

Series: Annual Reports in Combinatorial Chemistry & Molecular Diversity, 1

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Combinatorial chemistry and molecular diversity approaches to scientific inquiry and novel product R&D have exploded in the 1990s! For example, in the preparation of drug candidates, the automated, permutational, and combinatorial use of chemical building blocks now allows the generation and screening of unprecedented numbers of compounds. Drug discovery - better, faster, cheaper? Indeed, more compounds have been made and screened in the 1990s than in the last hundred years of pharmaceutical research.This first volume covers: (i) combinatorial chemistry, (ii) combinatorial biology and evolution, and (iii) informatics and related topics. Within each section chapters are prepared by experts in the field, including, for example, in Section I: Coverage of mixture pools vs. parallel individual compound synthesis, solution vs. solid-phase synthesis, analytical tools, and automation. Section II highlights selection strategies and library-based evolution, phage display, peptide and nucleic acid libraries. Section III covers databases and library design, high through-put screening, coding strategies vs. deconvolutions, intellectual property issues, deals and collaborations, and successes to date.

General

Imprint: Kluwer Academic Publishers
Country of origin: Netherlands
Series: Annual Reports in Combinatorial Chemistry & Molecular Diversity, 1
Authors: Walter H. Moos
Editors: Michael R. Pavia • B.K. Kay • A.D. Ellington
Format: Online resource
ISBN-13: 978-0-306-46904-6
Categories: Books > Professional & Technical > Industrial chemistry & manufacturing technologies > Industrial chemistry > Pharmaceutical technology
LSN: 0-306-46904-9
Barcode: 9780306469046

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