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Showing 1 - 6 of 6 matches in All departments

The End of the Line (DVD): George Duffield, Claire Lewis, Srdjan Kurpjel, Marios Takoushis The End of the Line (DVD)
George Duffield, Claire Lewis, Srdjan Kurpjel, Marios Takoushis; Directed by Rupert Murray
R128 Discovery Miles 1 280 Ships in 10 - 15 working days

Rupert Murray directs this documentary based on the book by Charles Clover about the devastating effects of over-fishing the world's oceans. Scientists predict that if fishing is continued at the current rate, the planet will run out of seafood by 2048 with catastrophic consequences. Murray travels the world examining the effects of diminishing fish stocks, asking who is responsible for setting and enforcing fish quotas and looking at possible solutions to this often overlooked problem.

Angiogenesis Assays - A Critical Appraisal of Current Techniques (Hardcover): Carolyn A. Staton, Claire Lewis, Roy Bicknell Angiogenesis Assays - A Critical Appraisal of Current Techniques (Hardcover)
Carolyn A. Staton, Claire Lewis, Roy Bicknell
R3,945 R3,712 Discovery Miles 37 120 Save R233 (6%) Ships in 10 - 15 working days

Angiogenesis, the development of new blood vessels from the existing vasculature, is essential for physiological growth and over 18,000 research articles have been published describing the role of angiogenesis in over 70 different diseases, including cancer, diabetic retinopathy, rheumatoid arthritis and psoriasis. One of the most important technical challenges in such studies has been finding suitable methods for assessing the effects of regulators of eh angiogenic response. While increasing numbers of angiogenesis assays are being described both in vitro and in vivo, it is often still necessary to use a combination of assays to identify the cellular and molecular events in angiogenesis and the full range of effects of a given test protein. Although the endothelial cell - its migration, proliferation, differentiation and structural rearrangement - is central to the angiogenic process, it is not the only cell type involved. the supporting cells, the extracellular matrix and the circulating blood with its cellular and humoral components also contribute.

In this book, experts in the use of a diverse range of assays outline key components of these and give a critical appraisal of their strengths and weaknesses. Examples include assays for the proliferation, migration and differentiation of endothelial cells in vitro, vessel outgrowth from organ cultures, assessment of endothelial and mural cell interactions, and such in vivo assays as the chick chorioallantoic membrane, zebrafish, corneal, chamber and tumour angiogenesis models. These are followed by a critical analysis of the biological end-points currently being used in clinical trials to assess the clinical efficacy ofanti-angiogenic drugs, which leads into a discussion of the direction future studies should take.

This valuable book will be of interest to research scientists currently working on angiogenesis in both the academic community and in the biotechnology and pharmaceutical industries. relevant disciplines include cell and molecular biology, oncology, cardiovascular research, biotechnology, pharmacology, pathology and physiology.

The Quest Everlasting, V3 - Launcelot and Guinevere Cycle (Hardcover): Thomas Howard Wilson The Quest Everlasting, V3 - Launcelot and Guinevere Cycle (Hardcover)
Thomas Howard Wilson; Foreword by Nettie Claire Lewis
R842 Discovery Miles 8 420 Ships in 7 - 11 working days

In Four Volumes. Volume 1, Adam And Eve Cycle; Volume 2, Anthony And Cleopatra Cycle; Volume 3, Launcelot And Guinevere Cycle; Volume 4, David And Constance Cycle.

The Quest Everlasting, V3 - Launcelot and Guinevere Cycle (Paperback): Thomas Howard Wilson The Quest Everlasting, V3 - Launcelot and Guinevere Cycle (Paperback)
Thomas Howard Wilson; Foreword by Nettie Claire Lewis
R541 Discovery Miles 5 410 Ships in 7 - 11 working days

In Four Volumes. Volume 1, Adam And Eve Cycle; Volume 2, Anthony And Cleopatra Cycle; Volume 3, Launcelot And Guinevere Cycle; Volume 4, David And Constance Cycle.

A Sick Work of Art (Paperback, New): Claire Lewis A Sick Work of Art (Paperback, New)
Claire Lewis
R276 Discovery Miles 2 760 Out of stock
The Psychoimmunology of Cancer (Hardcover, 2nd Revised edition): Claire Lewis, Rosalind O'Brien, Jennifer Barraclough The Psychoimmunology of Cancer (Hardcover, 2nd Revised edition)
Claire Lewis, Rosalind O'Brien, Jennifer Barraclough
R6,388 Discovery Miles 63 880 Ships in 7 - 11 working days

When the first edition of this book published in 1994, the psychoimmunology of cancer was still emerging as a topic for serious scientific study. Now, less than ten years later, there is a huge quantity of academic literature about the relationships between psychological variables, the immune system and cancer growth, accompanied by a lively popular interest.

In this new edition leading specialists have provided broad critical reviews of the different aspects. Part I, which presents the biological background, will be of particular interest to those with technical knowledge of the relevant laboratory based disciplines. It covers mechanisms mediating the effects of psychological status in the immune system, and anti-cancer mechanisms involving the immune system. Part II is clinically orientated, and accessible to a wide audience. Whether psychotherapeutic interventions can help patients live longer, as well as coping better, is obviously the key question and several contributors consider the clinical evidence for this. A new, speculative chapter on the spiritual context of immunity and cancer has also been added.

The psychoimmunology of cancer involves many complex issues, understanding of which remains far from complete. However, the contributors, besides reviewing the current state of knowledge and the implications for cancer patients, offer predictions for the future and ideas about further research.

From reviews of the first edition:

'The chief quality of this book is its presentation of an excellent but critical overview of the entire range of what is today called 'psychoimmunology', and it is to be recommended to all who are interested in the subject.' Annals of Oncology

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